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LEDGF Products

Antibodies
LEDGF Antibody (762815) [Unco ...
LEDGF Antibody (762815) [Unconjuga...
MAB3468
HAF018). Specific bands were detected for LEDGF p75 at approximately 75 kDa and LEDGF p52 at approximately 50-55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot LEDGF Antibody (762815) [Unconjugated]
NL007) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry LEDGF Antibody (762815) [Unconjugated]
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
LEDGF Antibody [Unconjugated] ...
LEDGF Antibody [Unconjugated]
AF3468
HAF017). Specific bands were detected for LEDGF p75 at approximately 75 kDa and LEDGF p52 at approximately 50-55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot LEDGF Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry LEDGF Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western LEDGF Antibody [Unconjugated]
HAF017). Specific bands were detected for LEDGF p75 at approximately 75 kDa and LEDGF p52 at approximately 49 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated LEDGF Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, ICC/IF, KO
Host: Goat Polyclonal
Proteins
Recombinant Human LEDGF Prote ...
Recombinant Human LEDGF Protein, CF
3468-LE
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human LEDGF p52 P ...
Recombinant Human LEDGF p52 Protei...
6044-LE
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
LEDGF Recombinant Protein Ant ...
LEDGF Recombinant Protein Antigen
NBP1-87885PEP
Species: Hu
Applications: AC

Description

The human p75 protein is a non TAF transcription coactivator that mediates activator dependent transcription by RNA polymerase II in vitro through most tested activators. Although p75 and p52 are derived from alternatively splicing of a single gene and share most coding sequence, they reveal different function in several aspects. In addition to functioning as a transcription coactivator, p75 has been reported to be involved in regulating growth of epithelial cells, pathogenesis of atopic dermatitis and activity of HIV1 integrase.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 11168
Alternate Names
  • CLL-associated antigen KW-7
  • Dense fine speckles 70 kDa protein
  • DFS70
  • LEDGFDFS 70
  • Lens epithelium-derived growth factor
  • MGC74712
  • p52
  • p75
  • PAIP
  • PC4 and SFRS1 interacting protein 1
  • PC4 and SFRS1 interacting protein 2
  • PC4 and SFRS1-interacting protein
  • PSIP2
  • transcriptional coactivator p52/p75
  • Transcriptional coactivator p75/p52

Research Areas for LEDGF

Find related products by research area and learn more about each of the different research areas below.

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Neuroscience