Human Free BDNF Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human Free BDNF Quantikine ELISA Kit Summary

• Background: The Quantikine Human BDNF Immunoassay is a 3.5 hour solid phase ELISA designed to measure human BDNF in cell culture supernates, serum, and plasma. It contains recombinant human BDNF expressed in Sf 21 cells and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant BDNF accurately. Results obtained measuring natural human BDN...F showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human BDNF.
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• Specificity: Natural and recombinant human BDNF
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: BDNF

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Interference observed with 1 or more available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Free BDNF Quantikine ELISA Kit

• Abrineurin
• ANON2
• BDNF
• brain-derived neurotrophic factor
• BULN2
• MGC34632
• Neurotrophin

Background

BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for BDNF (DBD00)(89)

Publications using DBD00

• M Nikolac Pe, F Borovecki, I Filipcic, B Vuic, T Milos, G Nedic Erja, M Konjevod, L Tudor, N Mimica, S Uzun, O Kozumplik, D Svob Strac, N Pivac Relationship between Brain-Derived Neurotrophic Factor and Cognitive Decline in Patients with Mild Cognitive Impairment and Dementia Biomolecules, 2023;13(3):. 2023-01-01 [PMID: 36979505] (Human)
• M Irfan, S Chung C5L2 modulates BDNF production in human dental pulp stem cells via p38alpha pathway Scientific Reports, 2023;13(1):74. 2023-01-01 [PMID: 36593314] (Human)
• V Sabrina, C Carmen, A Gloria, B Elisa, C Nico, B Marina, F Luigi, V Piera Impact of Freeze-Drying on Cord Blood (CB), Serum (S), and Platelet-Rich Plasma (CB-PRP) Preparations on Growth Factor Content and In Vitro Cell Wound Healing International Journal of Molecular Sciences, 2022;23(18):. 2022-01-01 [PMID: 36142617] (Human)
• J Rode, HMT Edebol Car, J König, AN Hutchinson, P Thunberg, J Persson, RJ Brummer Multi-Strain Probiotic Mixture Affects Brain Morphology and Resting State Brain Function in Healthy Subjects: An RCT Cells, 2022;11(18):. 2022-01-01 [PMID: 36139496] (Human)
• M Chroboczek, S Kujach, M ?uszczyk, T Grzywacz, H Soya, R Laskowski Acute Normobaric Hypoxia Lowers Executive Functions among Young Men despite Increase of BDNF Concentration International Journal of Environmental Research and Public Health, 2022;19(17):. 2022-01-01 [PMID: 36078520] (Human)
• M Karagyaur, D Dyikanov, P Tyurin-Kuz, S Dzhauari, M Skryabina, M Vigovskiy, A Primak, N Kalinina, V Tkachuk A Novel Cre/lox71-Based System for Inducible Expression of Recombinant Proteins and Genome Editing Cells, 2022;11(14):. 2022-01-01 [PMID: 35883584] (Human)
• S Dzhauari, S Litvinova, A Efimenko, N Aleksandru, N Basalova, M Abakumov, N Danilova, P Malkov, V Balabanyan, T Bezuglova, V Balayants, M Mnikhovich, M Gulyaev, M Skryabina, V Popov, D Stambolsky, T Voronina, V Tkachuk, M Karagyaur Urokinase-Type Plasminogen Activator Enhances the Neuroprotective Activity of Brain-Derived Neurotrophic Factor in a Model of Intracerebral Hemorrhage Biomedicines, 2022;10(6):. 2022-01-01 [PMID: 35740368] (Human)
• JM Kim, HJ Kang, JW Kim, M Jhon, W Choi, JY Lee, SW Kim, IS Shin, MG Kim, R Stewart Prospective associations of multimodal serum biomarkers with 12-week and 12-month remission in patients with depressive disorders receiving stepwise psychopharmacotherapy Brain, Behavior, and Immunity, 2022;104(0):65-73. 2022-01-01 [PMID: 35618226] (Human)
• B Stapel, D Fraccaroll, M Westhoff-B, J Bauersachs, R Lichtingha, K Jahn, A Burkert, V Buchholz, S Bleich, H Frieling, XQ Ding, KG Kahl Impact of fasting on stress systems and depressive symptoms in patients with major depressive disorder: a cross-sectional study Scientific Reports, 2022;12(1):7642. 2022-01-01 [PMID: 35538177] (Human)
• W Choi, JW Kim, HJ Kang, HK Kim, HC Kang, JY Lee, SW Kim, YJ Hong, Y Ahn, MH Jeong, R Stewart, JM Kim Interaction effects of diabetes and brain-derived neurotrophic factor on suicidal ideation in patients with acute coronary syndrome Scientific Reports, 2022;12(1):6602. 2022-01-01 [PMID: 35459929] (Human)
• M Jó?wiak-B?, P Soko?owska, M Siatkowska, CA Panek, P Komorowski, E Kowalczyk, A Wiktorowsk The Importance of Endoplasmic Reticulum Stress as a Novel Antidepressant Drug Target and Its Potential Impact on CNS Disorders Pharmaceutics, 2022;14(4):. 2022-01-01 [PMID: 35456680] (Human)
• L Hernandez, LJ Ward, S Arefin, T Ebert, A Laucyte-Ci, GOING-FWD, O Heimbürger, P Barany, L Wennberg, P Stenvinkel, K Kublickien Blood-brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins Scientific Reports, 2022;12(1):4414. 2022-01-01 [PMID: 35292710] (Human)
• HA Fachim, N Malipatil, K Siddals, R Donn, GY Cortés, CF Dalton, JM Gibson, AH Heald Methylation Status of Exon IV of the Brain-Derived Neurotrophic Factor (BDNF)-Encoding Gene in Patients with Non-Diabetic Hyperglycaemia (NDH) before and after a Lifestyle Intervention Epigenomes, 2022;6(1):. 2022-01-01 [PMID: 35225959] (Human)
• H Soloey-Nil, K Nygaard-Od, MG Kristianse, OL Brekke, TE Mollnes, SK Reitan, T Oiesvold Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients BMC Psychiatry, 2022;22(1):84. 2022-01-01 [PMID: 35114967] (Human)
• YC Liu, HT Hsiao, JC Wang, TC Wen, SL Chen TGF-beta1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis PLoS ONE, 2022;17(1):e0262074. 2022-01-01 [PMID: 35061744] (Human)
• SY Lee, TY Wang, RB Lu, LJ Wang, CH Chang, YC Chiang, CC Pan, KW Tsai Plasma BDNF and Cytokines Correlated with Protein Biomarkers for Bipolar II Disorder Journal of personalized medicine, 2021;11(12):. 2021-01-01 [PMID: 34945756] (Human)
• T Ogawa, SP Hoekstra, YI Kamijo, VL Goosey-Tol, JJ Walsh, F Tajima F, CA Leicht Serum and plasma brain-derived neurotrophic factor concentration are elevated by systemic but not local passive heating PLoS ONE, 2021;16(12):e0260775. 2021-01-01 [PMID: 34882699] (Human)
• SJ Pressler, M Jung, I Gradus-Piz, M Titler, D Smith, S Gao, KR Lake, H Burney, D Clark, K Wierenga, SG Dorsey, B Giordani Randomized Controlled Trial of a Cognitive Intervention to Improve Memory in Heart Failure Journal of cardiac failure, 2021;0(0):. 2021-01-01 [PMID: 34763080] (Human)
• CA Farmer, AE Thurm, B Honnekeri, P Kim, SE Swedo, JC Han The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder Scientific Reports, 2021;11(1):18158. 2021-01-01 [PMID: 34518555] (Human)
• R Solianik, D Mickevi?ie, L Žlibinait?, A ?ekanauska Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic Experimental gerontology, 2021;150(0):111363. 2021-01-01 [PMID: 33887380] (Human)
• R Markiewicz, B Dobrowolsk Reinforcement of Self-Regulated Brain Activity in Schizophrenia Patients Undergoing Rehabilitation BioMed Research International, 2021;2021(0):8030485. 2021-01-01 [PMID: 33855083] (Human)
• M Koz?owska, J Kortas, M ?ychowska, J Antosiewic, K ?uczek, S Perego, G Lombardi, E Ziemann Beneficial effects of whole-body cryotherapy on glucose homeostasis and amino acid profile are associated with a reduced myostatin serum concentration Scientific Reports, 2021;11(1):7097. 2021-01-01 [PMID: 33782504] (Human)
• ?A Poniatowsk, A Cudna, K Kurczych, E Bronisz, I Kurkowska- Kinetics of serum brain-derived neurotrophic factor (BDNF) concentration levels in epileptic patients after generalized tonic-clonic seizures Epilepsy research, 2021;173(0):106612. 2021-01-01 [PMID: 33774427] (Human)
• SY Lee, TY Wang, RB Lu, LJ Wang, CH Chang, YC Chiang, KW Tsai Peripheral BDNF correlated with miRNA in BD-II patients Journal of psychiatric research, 2021;136(0):184-189. 2021-01-01 [PMID: 33610945] (Human)
• JL Steinhäuse, JA King, FI Tam, M Seidel, R Biemann, ML Wronski, D Geisler, V Roessner, S Ehrlich Is Serum BDNF Altered in Acute, Short- and Long-Term Recovered Restrictive Type Anorexia Nervosa? Nutrients, 2021;13(2):. 2021-01-01 [PMID: 33572701] (Human)
• R von Känel, M Hamer, A Wentzel, L Malan Circulating neurotrophins and hemostatic risk factors of atherothrombotic cardiovascular disease at baseline and during sympathetic challenge: the SABPA study Scientific Reports, 2021;11(1):2297. 2021-01-01 [PMID: 33504912] (Human)
• FJ Raucci, AP Singh, J Soslow, LW Markham, L Zhong, W Aljafar, N Lessiohadi, CP Awgulewits, P Umbarkar, Q Zhang, PL Cannon, M Buchowski, JT Roland, EJ Carrier, WB Burnette, AK Hatzopoulo, H Lal, CL Galindo The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy Int J Mol Sci, 2020;21(20):. 2020-01-01 [PMID: 33050457] (Human)
• M Tylicka, E Matuszczak, A Hermanowic, W D?bek, M Karpi?ska, J Kami?ska, OM Koper-Lenk BDNF and IL-8, But Not UCHL-1 and IL-11, Are Markers of Brain Injury in Children Caused by Mild Head Trauma Brain sciences, 2020;10(10):. 2020-01-01 [PMID: 32987792] (Human)
• Z Piotrowicz, M Chalimoniu, K P?oszczyca, M Czuba, J Langfort Exercise-Induced Elevated BDNF Level Does Not Prevent Cognitive Impairment Due to Acute Exposure to Moderate Hypoxia in Well-Trained Athletes Int J Mol Sci, 2020;21(15):. 2020-01-01 [PMID: 32759658] (Human)
• C Rezola-Par, G Hervás, H Arrieta, AH Diego, F Ruiz-Litag, SM Gil, A Rodriguez-, J Irazusta Physical exercise interventions have no effect on serum BDNF concentration in older adults living in long-term nursing homes Exp. Gerontol., 2020;139(0):111024. 2020-01-01 [PMID: 32693009] (Human)
• W Theilmann, M Rosenholm, P Hampel, W Löscher, T Rantamäki Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress PLoS ONE, 2020;15(6):e0235046. 2020-01-01 [PMID: 32579566] (Rat)
• AL Shiozawa, T Igarashi, M Kobayashi, K Nakamoto, S Kameya, S Fujishita, H Takahashi, T Okada Tyrosine triple mutated AAV2-BDNF gene therapy in an inner retinal injury model induced by intravitreal injection of N-methyl-D-aspartate (NMDA) Mol. Vis., 2020;26(0):409-422. 2020-01-01 [PMID: 32565669] (Transgenic Mouse)
• A ?ekanauska, A Skurvydas, L Žlibinait?, D Mickevi?ie, S Kilikevi?i, R Solianik A 10-week yoga practice has no effect on cognition, but improves balance and motor learning by attenuating brain-derived neurotrophic factor levels in older adults Exp. Gerontol., 2020;138(0):110998. 2020-01-01 [PMID: 32544572] (Human)
• C Wu, J Lu, S Lu, M Huang, Y Xu Increased ratio of mature BDNF to precursor-BDNF in patients with major depressive disorder with severe anhedonia J Psychiatr Res, 2020;126(0):92-97. 2020-01-01 [PMID: 32428748] (Human)
• NF Kasim, JV van Zanten, S Aldred Tai Chi is an effective form of exercise to reduce markers of frailty in older age Exp. Gerontol., 2020;135(0):110925. 2020-01-01 [PMID: 32184194] (Human)
• J Nilsson, Ö Ekblom, M Ekblom, A Lebedev, O Tarassova, M Moberg, M Lövdén Acute increases in brain-derived neurotrophic factor in plasma following physical exercise relates to subsequent learning in older adults Sci Rep, 2020;10(1):4395. 2020-01-01 [PMID: 32157099] (Human)
• KL Szuhany, MW Otto Assessing BDNF as a mediator of the effects of exercise on depression J Psychiatr Res, 2020;123(0):114-118. 2020-01-01 [PMID: 32065946] (Human)
• H Arrieta, C Rezola-Par, M Kortajaren, G Hervás, J Gil, JJ Yanguas, M Iturburu, SM Gil, J Irazusta, A Rodriguez- The impact of physical exercise on cognitive and affective functions and serum levels of brain-derived neurotrophic factor in nursing home residents: A randomized controlled trial Maturitas, 2020;131(0):72-77. 2020-01-01 [PMID: 31787150] (Human)
• D Hao, C He, B Ma, L Lankford, L Reynaga, DL Farmer, F Guo, A Wang Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering Stem Cells Int, 2019;2019(0):9695239. 2019-01-01 [PMID: 31781252] (Human)
• F Scarpina, P Marzullo, S Mai, A Mauro, M Scacchi, M Costantini Altered temporal sensitivity in obesity is linked to pro-inflammatory state Sci Rep, 2019;9(1):15508. 2019-01-01 [PMID: 31664059] (Human)
• ML Schmalhofe, MRP Markus, JC Gras, J Kopp, D Janowitz, HJ Grabe, S Gro beta , R Ewert, S Gläser, D Albrecht, I Eiffler, H Völzke, N Friedrich, M Nauck, A Steveling, S Könemann, K Wenzel, SB Felix, M Dörr, M Bahls Sex-Specific Associations of Brain-Derived Neurotrophic Factor and Cardiorespiratory Fitness in the General Population Biomolecules, 2019;9(10):. 2019-01-01 [PMID: 31635145] (Human)
• R Lejkowska, MP Kawa, E Pius-Sadow, D Rogi?ska, K ?uczkowska, B Machali?sk, A Machali?sk Preclinical Evaluation of Long-Term Neuroprotective Effects of BDNF-Engineered Mesenchymal Stromal Cells as Intravitreal Therapy for Chronic Retinal Degeneration in Rd6 Mutant Mice Int J Mol Sci, 2019;20(3):. 2019-01-01 [PMID: 30759764] (Transgenic Mouse)
• F Russo, G Chimienti, G Riezzo, M Linsalata, B D'Attoma, C Clemente, A Orlando Adipose Tissue-Derived Biomarkers of Intestinal Barrier Functions for the Characterization of Diarrhoea-Predominant IBS Dis. Markers, 2018;2018(0):1827937. 2018-01-01 [PMID: 30622656] (Human)
• MH Lin, CY Chung, KT Chen, JC Yeh, TH Lee, MH Lee, IN Lee, WC Huang, JT Yang Comparison between Polybutylcyanoacrylate Nanoparticles with Either Surface-Adsorbed or Encapsulated Brain-Derived Neurotrophic Factor on the Neural Differentiation of iPSCs Int J Mol Sci, 2019;20(1):. 2019-01-01 [PMID: 30621332] (N/A)
• J Jaworska, K Micielska, M Koz?owska, K Wnorowski, J Skrobecki, L Radzimi?sk, A Babi?ska, E Rodziewicz, G Lombardi, E Ziemann A 2-Week Specific Volleyball Training Supported by the Whole Body Cryostimulation Protocol Induced an Increase of Growth Factors and Counteracted Deterioration of Physical Performance Front Physiol, 2018;9(0):1711. 2018-01-01 [PMID: 30555349] (Human)
• TT Yeh, KC Chang, CY Wu, YY Lee, PY Chen, JW Hung Effects and mechanism of the HECT study (hybrid exercise-cognitive trainings) in mild ischemic stroke with cognitive decline: fMRI for brain plasticity, biomarker and behavioral analysis Contemp Clin Trials Commun, 2018;9(0):164-171. 2018-01-01 [PMID: 29696239] (Human)
• T Oka, T Tanahashi, N Sudo, B Lkhagvasur, Y Yamada Changes in fatigue, autonomic functions, and blood biomarkers due to sitting isometric yoga in patients with chronic fatigue syndrome Biopsychosoc Med, 2018;12(0):3. 2018-01-01 [PMID: 29643935] (Human)
• T Osaki, V Sivathanu, RD Kamm Engineered 3D vascular and neuronal networks in a microfluidic platform Sci Rep, 2018;8(1):5168. 2018-01-01 [PMID: 29581463] (Human)
• CC Charalambo, CC Alcantara, MA French, X Li, KS Matt, HE Kim, SM Morton, DS Reisman A single exercise bout and locomotor learning after stroke: physiological, behavioral, and computational outcomes J. Physiol. (Lond.), 2018;0(0):. 2018-01-01 [PMID: 29569729] (Human)
• L Woost, PL Bazin, M Taubert, R Trampel, CL Tardif, A Garthe, G Kempermann, U Renner, G Stalla, DVM Ott, V Rjosk, H Obrig, A Villringer, E Roggenhofe, TA Klein Physical Exercise and Spatial Training: A Longitudinal Study of Effects on Cognition, Growth Factors, and Hippocampal Plasticity Sci Rep, 2018;8(1):4239. 2018-01-01 [PMID: 29523857] (Human)
• A Gmi?t, J Jaworska, K Micielska, J Kortas, K Prusik, K Prusik, M Lipowski, A Radulska, N Szupryczy?, J Antosiewic, E Ziemann Improvement of cognitive functions in response to a regular Nordic walking training in elderly women - A change dependent on the training experience Exp. Gerontol., 2018;104(0):105-112. 2018-01-01 [PMID: 29432893] (ELISA Capture, Human)
• YR Kim, SM Ahn, ME Pak, HJ Lee, DH Jung, YI Shin, HK Shin, BT Choi Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke Sci Rep, 2018;8(1):2044. 2018-01-01 [PMID: 29391466] (Mouse)
• CS Chu, CL Chu, CC Wu, T Lu Serum nerve growth factor beta, brain- and glial-derived neurotrophic factor levels and psychopathology in unmedicated patients with schizophrenia J Chin Med Assoc, 2018;0(0):. 2018-01-01 [PMID: 29366645] (Human)
• KL Bharani, R Derex, AC Granholm, A Ledreux A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats PLoS ONE, 2017;12(12):e0189821. 2017-01-01 [PMID: 29261743] (Rat)
• S Chen, H Jiang, Y Liu, Z Hou, Y Yue, Y Zhang, F Zhao, Z Xu, Y Li, X Mou, L Li, T Wang, J Zhao, C Han, Y Sui, M Wang, Z Yang, Y Lu, Y Zhu, J Li, X Shen, F Sun, Q Chen, H Chen, Y Yuan Combined serum levels of multiple proteins in tPA-BDNF pathway may aid the diagnosis of five mental disorders Sci Rep, 2017;7(1):6871. 2017-01-01 [PMID: 28761093] (Human)
• MS Rahman, V Millischer, Z Zeebari, Y Forsell, C Lavebratt BDNF Val66Met and childhood adversity on response to physical exercise and internet-based cognitive behavioural therapy in depressed Swedish adults J Psychiatr Res, 2017;93(0):50-58. 2017-01-01 [PMID: 28578208] (Human)
• SY Cho, WY So, HT Roh The Effects of Taekwondo Training on Peripheral Neuroplasticity-Related Growth Factors, Cerebral Blood Flow Velocity, and Cognitive Functions in Healthy Children: A Randomized Controlled Trial Int J Environ Res Public Health, 2017;14(5):. 2017-01-01 [PMID: 28441325] (Human)
• H Jiang, S Chen, C Li, N Lu, Y Yue, Y Yin, Y Zhang, X Zhi, D Zhang, Y Yuan The serum protein levels of the tPA-BDNF pathway are implicated in depression and antidepressant treatment Transl Psychiatry, 2017;7(4):e1079. 2017-01-01 [PMID: 28375203] (Human)
• Tao Huang Cross-sectional associations of objectively-measured physical activity with brain-derived neurotrophic factor in adolescents Physiol. Behav, 2016;0(0):. 2016-01-01 [PMID: 28027935] (Human)
• Shobhit Sharma Stress-induced change in serum BDNF is related to quantitative family history of alcohol use disorder and age at first alcohol use Pharmacol. Biochem. Behav, 2016;153(0):12-17. 2016-01-01 [PMID: 27939343] (Human)
• E Valassi Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels Eur. J. Endocrinol, 2017;176(2):221-231. 2017-01-01 [PMID: 27932530] (Human)
• Rohit Bhatia Paracrine Mechanisms of Intravenous Bone Marrow-Derived Mononuclear Stem Cells in Chronic Ischemic Stroke Cerebrovasc Dis Extra, 2016;6(3):107-119. 2016-01-01 [PMID: 27846623] (Human)
• Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke Stem Cells Int, 2016;2016(0):6104780. 2016-01-01 [PMID: 27840648] (Human)
• Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling Sci Rep, 2016;6(0):29029. 2016-01-01 [PMID: 27374240] (Human)
• Exploring the Association between Serum BDNF and Attempted Suicide Sci Rep, 2016;6(0):25229. 2016-01-01 [PMID: 27121496] (Human)
• Nomoto H, Baba H, Satomura E, Maeshima H, Takebayashi N, Namekawa Y, Suzuki T, Arai H Serum brain-derived neurotrophic factor levels and personality traits in patients with major depression. BMC Psychiatry, 2015;15(0):33. 2015-01-01 [PMID: 25885038] (Human)
• Kim H, Suzuki T, Kim M, Kojima N, Ota N, Shimotoyodome A, Hase T, Hosoi E, Yoshida H Effects of exercise and milk fat globule membrane (MFGM) supplementation on body composition, physical function, and hematological parameters in community-dwelling frail Japanese women: a randomized double blind, placebo-controlled, follow-up trial. PLoS ONE, 2015;10(2):e0116256. 2015-01-01 [PMID: 25659147] (Human)
• Chen , Shiou-La, Lee , Sheng-Yu, Chang , Yun-Hsua, Wang , Tzu-Yun, Chen , Shih-Hen, Chu , Chun-Hsi, Chen , Po See, Yang , Yen Kuan, Hong , Jau-Shyo, Lu , Ru-Band The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients. Sci Rep, 2015;5(0):8148. 2015-01-01 [PMID: 25640280] (Human)
• Chou M, Burnouf T, Wang T Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate. PLoS ONE, 2014;9(6):e99145. 2014-01-01 [PMID: 24945500] (Human)
• Park Y, Lee B, Um T, Kim S Serum BDNF levels in relation to illness severity, suicide attempts, and central serotonin activity in patients with major depressive disorder: a pilot study. PLoS ONE, 2014;9(3):e91061. 2014-01-01 [PMID: 24663244] (Human)
• Rizos E, Papathanasiou M, Michalopoulou P, Laskos E, Mazioti A, Kastania A, Vasilopoulou K, Nikolaidou P, Margaritis D, Papageorgiou C, Liappas I A longitudinal study of alterations of hippocampal volumes and serum BDNF levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia. PLoS ONE, 2014;9(2):e87997. 2014-01-01 [PMID: 24551075] (Human)
• Suriyaprom , Kanjana, Tungtrongchitr , Rungsunn, Thawnasom , Kittisak Measurement of the levels of leptin, BDNF associated with polymorphisms LEP G2548A, LEPR Gln223Arg and BDNF Val66Met in Thai with metabolic syndrome. Diabetol Metab Syndr, 2014;6(1):6. 2014-01-01 [PMID: 24444121] (Human)
• Hohenadel M, Thearle M, Grice B, Huang H, Dai M, Tao Y, Hunter L, Palaguachi G, Mou Z, Kim R, Tsang M, Haack K, Voruganti V, Cole S, Butte N, Comuzzie A, Muller Y, Baier L, Krakoff J, Knowler W, Yanovski J, Han J Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants. Int J Obes (Lond), 2014;38(8):1068-74. 2014-01-01 [PMID: 24276017] (Human)
• Azoulay , David, Lavie , David, Horowitz , Netanel, Suriu , Celia, Gatt , Moshe E, Akria , Luiza, Perlman , Riki, Braester , Andrei, Ben-Yehuda , Dina Bortezomib-induced peripheral neuropathy is related to altered levels of brain-derived neurotrophic factor in the peripheral blood of patients with multiple myeloma. Br J Haematol, 2014;164(3):454-6. 2014-01-01 [PMID: 24164472] (Human)
• Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS ONE, 2013;8(4):e61483. 2013-01-01 [PMID: 23585901] (Human)
• Tirassa P, Iannitelli A, Sornelli F, Cirulli F, Mazza M, Calza A, Alleva E, Branchi I, Aloe L, Bersani G, Pacitti F Daily serum and salivary BDNF levels correlate with morning-evening personality type in women and are affected by light therapy. Riv Psichiatr, 0;47(6):527-34. [PMID: 23160113]
• Rossing K, Novak N, Mommert S, Pfab F, Gehring M, Wedi B, Kapp A, Raap U Brain-derived neurotrophic factor is increased in serum and skin levels of patients with chronic spontaneous urticaria. Clin. Exp. Allergy, 2011;41(10):1392-1399. 2011-01-01 [PMID: 21676041] (Human)
• Sobrino T, Arias S, Perez-Mato M, Agulla J, Brea D, Rodriguez-Yanez M, Castillo J CD34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans. J. Neurosci. Res., 2011;89(7):979-85. 2011-01-01 [PMID: 21488087] (Human)
• Erickson KI, Voss MW, Prakash RS Exercise training increases size of hippocampus and improves memory. Proc. Natl. Acad. Sci. U.S.A., 2011;108(7):3017-22. 2011-01-01 [PMID: 21282661] (Human)
• Huang YT, Lai PC, Wu CC, Hsu SH, Cheng CC, Lan YF, Chiu TH BDNF mediated TrkB activation is a survival signal for transitional cell carcinoma cells. Int. J. Oncol., 2010;36(6):1469-76. 2010-01-01 [PMID: 20428771] (Human)
• Seifert T, Brassard P, Wissenberg M, Rasmussen P, Nordby P, Stallknecht B, Adser H, Jakobsen AH, Pilegaard H, Nielsen HB, Secher NH Endurance training enhances BDNF release from the human brain. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2010;298(2):R372-7. 2010-01-01 [PMID: 19923361] (Human)
• Verhovshek T, Cai Y, Osborne MC, Sengelaub DR Androgen regulates brain-derived neurotrophic factor in spinal motoneurons and their target musculature. Endocrinology, 2010;151(1):253-61. 2010-01-01 [PMID: 19880806] (Rat)
• Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res., 2008;68(23):9996-10003. 2008-01-01 [PMID: 19047182] (Human)
• Golder FJ, Ranganathan L, Satriotomo I, Hoffman M, Lovett-Barr MR, Watters JJ, Baker-Herman TL, Mitchell GS Spinal adenosine A2a receptor activation elicits long-lasting phrenic motor facilitation. J. Neurosci., 2008;28(9):2033-42. 2008-01-01 [PMID: 18305238] (Rat)
• Laske C, Stransky E, Leyhe T, Eschweiler GW, Schott K, Langer H, Gawaz M Decreased brain-derived neurotrophic factor (BDNF)- and beta-thromboglobulin (beta-TG)- blood levels in Alzheimer's disease. Thromb. Haemost., 2006;96(1):102-3. 2006-01-01 [PMID: 16807663] (Human)
• Angelucci F, Oliviero A, Pilato F, Saturno E, Dileone M, Versace V, Musumeci G, Batocchi AP, Tonali PA, Di Lazzaro V Transcranial magnetic stimulation and BDNF plasma levels in amyotrophic lateral sclerosis. Neuroreport, 2004;15(4):717-20. 2004-01-01 [PMID: 15094483] (Human)
• Mahmood A, Lu D, Chopp M Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury. J. Neurotrauma, 2004;21(1):33-9. 2004-01-01 [PMID: 14987463] (Rat)
• Malamitsi-Puchner A, Economou E, Rigopoulou O, Boutsikou T Perinatal changes of brain-derived neurotrophic factor in pre- and fullterm neonates. Early Hum. Dev., 2004;76(1):17-22. 2004-01-01 [PMID: 14729159] (Human)
• Truckenmiller ME, Vawter MP, Zhang P, Conejero-Goldberg C, Dillon-Carter O, Morales N, Cheadle C, Becker KG, Freed WJ AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp. Neurol., 2002;175(0):318. 2002-01-01 [PMID: 12061863] (Rat)

Bioinformatics

• Gene Symbol: BDNF