Western Blot: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Loading: 20ug of lysates per lane.Antibodies: IL-23, (2 ug/mL), 1h incubation at RT in 5% NFDM/TBST.Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 ...read more
Immunocytochemistry/ Immunofluorescence: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Immunofluorescence of IL-23 in Raji cells with IL-23 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Abdominal Aortic Aneurysm (AAA) Tissues (Validation of IL-23 in Human Abdominal Aortic Aneurysm (AAA) Tissues
Western Blot: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Western blot analysis of IL-23 in Raji lysate with IL-23 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
Western Blot: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Loading: 30 ng of human IL-23 recombinant protein.Antibodies: IL-23 (4 ug/mL), 1h incubation at RT in 5% NFDM/TBST.Secondary: Goat anti-rabbit IgG HRP conjugate at ...read more
Immunocytochemistry/ Immunofluorescence: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Raji cells with IL-23 P19 antibody at 10 ug/ml.
Immunocytochemistry/ Immunofluorescence: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Human pancreas tissue with IL-23 antibody at 20 ug/ml.
Immunohistochemistry: IL-23A/IL-23 P19 Antibody [NBP1-77257] - Staining of human pancreas tissue with antibody at 5 ug/mL.
Antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IL-23. The immunogen is located within the last 50 amino acids of IL-23. Amino Acid Squence: QIPSLSPSQPWQRL
Guinea Pig (93%), Equine (93%). Backed by our 100% Guarantee.
Peptide affinity purified
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Use in immunoprecipitation reported in scientific literature (PMID: 29650963).
21 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Peptide affinity purified
Alternate Names for IL-23A/IL-23 P19 Antibody
IL-23 p19/IL-12 p40
interleukin 23 p19 subunit
interleukin 23, alpha subunit p19
interleukin-23 subunit alpha
Interleukin-23 subunit p19
JKA3 induced upon T-cell activation
SGRFIL-23 subunit alpha
Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.