Human IL-37/IL-1F7 DuoSet ELISA, 15 Plate



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

Order Details

Human IL-37/IL-1F7 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY1975.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-37/IL-1F7 DuoSet ELISA, 15 Plate

  • FIL1 zeta
  • FIL1
  • FIL1(ZETA)
  • FIL1ZFIL1 zeta
  • IL-1F7
  • IL-1F7IL-1 zeta
  • IL1H4IL1F7 (canonical product IL-1F7b)
  • IL-1H4IL-1F7b (IL-1H4, IL-1H, IL-1RP1)
  • IL-1RP1IL-1X protein
  • IL1RP1interleukin 1 family member 7
  • IL-1X
  • IL37
  • IL-37
  • interleukin 1 family, member 7 (zeta)
  • interleukin 1, zeta
  • interleukin-1 family member 7
  • Interleukin-1 homolog 4
  • interleukin-1 superfamily z
  • Interleukin-1 zeta
  • Interleukin-1-related protein


Human interleukin 37, also named IL-1F7, FIL1 zeta, IL-1H4, and IL-1rp1, belongs to the IL-1 cytokine family. With the exception of IL-18 that maps to human chromosome 11, all IL-1 family members map to the same cluster on human chromosome 2. Mouse IL-37 has not been reported, but human IL-37 is active on mouse cells. Five isoforms (IL-37a through e) are generated through alternative exon usage and have distinct expression profiles. Like IL-1 alpha, IL-1 beta and IL-18, all of the IL-37 variants lack a typical signal peptide.

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Publications for IL-37/IL-1F7 (DY1975)(13)

We have publications tested in 2 confirmed species: Human, Mouse.

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Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using DY1975 Applications Species
D Kabelitz, M Zarobkiewi, M Heib, R Serrano, M Kunz, G Chitadze, D Adam, C Peters Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes Scientific Reports, 2022-10-24;12(1):17827. 2022-10-24 [PMID: 36280676] (Human) Human
N Ma, C Yuan, J Shi, Q Zhu, Y Liu, X Ma, B Li, W Gong, J Xue, G Lu, W Li, J Li Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis JCI Insight, 2022-11-08;0(0):. 2022-11-08 [PMID: 36166295] (Human) Human
DG Osborne, J Domenico, M Fujita Expression of IL-37 Induces a Regulatory T-Cell-like Phenotype and Function in Jurkat Cells Cells, 2022-08-18;11(16):. 2022-08-18 [PMID: 36010641] (Human) Human
F La Rosa, S Agostini, M Saresella, AS Costa, F Piancone, R Miglioli, F Trecate, M Clerici Deregulation of IL-37 and its miRNAs modulators in sarcopenic patients after rehabilitation Journal of Translational Medicine, 2021-04-26;19(1):172. 2021-04-26 [PMID: 33902634] (Human) Human
V Paixão, EB Almeida, JB Amaral, T Roseira, FR Monteiro, R Foster, A Sperandio, M Rossi, GR Amirato, CAF Santos, RS Pires, FB Leal, EL Durigon, DBL Oliveira, RP Vieira, M Vaisberg, JMB Santos, ALL Bachi Elderly Subjects Supplemented with L-Glutamine Shows an Improvement of Mucosal Immunity in the Upper Airways in Response to Influenza Virus Vaccination Vaccines, 2021-01-31;9(2):. 2021-01-31 [PMID: 33572639] (Human) Human
A Radujkovic, T Boch, F Nolte, D Nowak, C Kunz, A Gieffers, C Müller-Tid, P Dreger, WK Hofmann, T Luft Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile Cancers, 2020-12-08;12(12):. 2020-12-08 [PMID: 33302451] (Human) Human
T Zhao, F Jin, D Xiao, H Wang, C Huang, X Wang, S Gao, J Liu, S Yang, J Hao IL-37/ STAT3/ HIF-1&alpha negative feedback signaling drives gemcitabine resistance in pancreatic cancer Theranostics, 2020-03-04;10(9):4088-4100. 2020-03-04 [PMID: 32226541] (Human) Human
K Moideen, NP Kumar, R Bethunaick, VV Banurekha, D Nair, S Babu Heightened systemic levels of anti-inflammatory cytokines in pulmonary tuberculosis and alterations following anti-tuberculosis treatment Cytokine, 2019-12-04;127(0):154929. 2019-12-04 [PMID: 31811994] (Human) Human
A Merz, U Germing, G Kobbe, J Kaivers, A Jauch, A Radujkovic, M Hummel, A Benner, M Merz, P Dreger, T Luft EASIX for prediction of survival in lower-risk myelodysplastic syndromes Blood Cancer J, 2019-11-11;9(11):85. 2019-11-11 [PMID: 31712595] (Human) Human
Y Zhao, X Ni, P Xu, Q Liu, T Sun, X Liu, X Ji, J Qiu, J Li, S Wang, P Han, J Peng, M Hou, G Li Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP) Cytokine, 2019-09-23;125(0):154853. 2019-09-23 [PMID: 31557634] (Human) Human
Show All 13 Publications.

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Gene Symbol IL37