eIF4A2 Antibody (PCRP-EIF4A2-2B5) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: ELISA, MA
• Clone: PCRP-EIF4A2-2B5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

eIF4A2 Antibody (PCRP-EIF4A2-2B5) [Alexa Fluor™ Plus 594] Summary

• Immunogen: Recombinant full-length human eIF4A2 protein (Uniprot: Q14240)
• Localization: Nucleus.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: EIF4A2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Protein Array
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to work in Chick, Mouse, Rat, Xenopus and Zebrafish.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for eIF4A2 Antibody (PCRP-EIF4A2-2B5) [Alexa Fluor™ Plus 594]

• ATP-dependent RNA helicase eIF4A-2
• BM-010
• DDX2Beukaryotic translation initiation factor 4A, isoform 2
• EC 3.6.1
• EC 3.6.4.13
• EIF4A
• eIF-4A-II
• eIF4A-II
• EIF4F
• eukaryotic initiation factor 4A-II
• eukaryotic translation initiation factor 4A
• eukaryotic translation initiation factor 4A2

Background

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and isrequired for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondarystructures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, andsubsequent scanning for the initiator codon

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EIF4A2