DAX1/NR0B1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: DAX1/NR0B1 Antibody [NBP1-32832] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: NR0B1 protein stained by NR0B1 antibody diluted at 1:200. Red: ...read more
Immunohistochemistry-Paraffin: DAX1/NR0B1 Antibody [NBP1-32832] - Paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, Pm, RMSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.4 mg/ml

Order Details

DAX1/NR0B1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human NR0B1. The exact sequence is proprietary.
Localization
Nucleus, Cytoplasm
Predicted Species
Primate (99%), Rhesus Macaque (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR0B1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (99%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.4 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DAX1/NR0B1 Antibody

  • AHC
  • AHCDSS
  • AHCH
  • AHX
  • DAX1
  • DAX1DAX-1
  • dosage-sensitive sex reversal
  • DSS-AHC critical region on the X chromosome protein 1
  • GTD
  • HHG
  • NR0B1
  • NROB1
  • nuclear hormone receptor
  • Nuclear receptor DAX-1
  • nuclear receptor subfamily 0 group B member 1
  • nuclear receptor subfamily 0, group B, member 1

Background

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional DAX1/NR0B1 Products

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Bioinformatics

Gene Symbol NR0B1
Entrez
Uniprot