Western Blot: LRH-1/NR5A2 Antibody [NBP2-27196] - Analysis of NR5A2 in HEPG2 lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse NIH3T3 and 4) RAW lysate probed with 3 ug/ml of NR5A2 antibody. Goat ...read more
Immunohistochemistry-Paraffin: LRH-1/NR5A2 Antibody [NBP2-27196] - Analysis of NR5A2/LRH1 in human pancreas tissue using NR5A2/LRH1 antibody at 5 ug/ml.
Orangutan (100%), Chimpanzee (100%), New World Monkey (100%), Panda (100%), Great Ape (100%), Mole Rat (100%), White cheeked gibbon (100%), Platypus (100%), Zebra finch (100%), Catfish (100%), Frog (100%), Carolina anole (100%)
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein A purified
Alternate Names for LRH-1/NR5A2 Antibody
Alpha-1-fetoprotein transcription factor
b1-binding factor, hepatocyte transcription factor which activates enhancer IIof hepatitis B virus
fetoprotein-alpha 1 (AFP) transcription factor
hB1FCYP7A promoter-binding factor
Hepatocytic transcription factor
Liver receptor homolog 1
liver receptor homolog-1
nuclear receptor NR5A2
nuclear receptor subfamily 5 group A member 2
nuclear receptor subfamily 5, group A, member 2
NR5A2 is a member of the so-called NR5A family of nuclear receptors. NR5A2, also call LRH1 or Liver Receptor Homolog 1, appears to play an important role in regulating pancreatic and embryonal stem cell differentiation maintaining a pluripotential or undifferentiated state. It also plays a role in controlling cholesterol balance (1, 2). NR5A2 may control pluripotentiality through its regulation of Oct4 and Nanog, both are commonly held as requisite factors for maintenance of stem cell undifferentiated states (3). Additionally, NR5A2 has a role in colon, pancreatic and breast cancer, accompanied by overexpression in the latter in ductal carcinomas (4, 5). Antibody to NR5A2 provides a tool to link expression and function with undifferentiated states in embryonic stem cells or in cancers of the breast, intestine, and pancreas, and for further characterization of NR5A2 as a potential biomarker.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.