Western Blot: CD68/SR-D1 Antibody (KP1) - Unpurified [NB100-683] - Total protein from human spleen was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The ...read more
Immunohistochemistry-Paraffin: CD68/SR-D1 Antibody (KP1) - Unpurified [NB100-683] - CD68/SR-D1 Antibody (KP1) [NB100-683] - Analysis of a FFPE human spleen tissue section using 1:10 dilution of CD68/SR-D1 antibody ...read more
Flow Cytometry: CD68/SR-D1 Antibody (KP1) [NB100-683] - An intracellular stain was performed on THP-1 cells with CD68/SR-D1 Antibody NB100-683 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA ...read more
IHC: For an ABC system, dilute 1:20 and incubate for 30-60 minutes at RT. IHC-P tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Use in Flow Cytometry reported in scientific literature (PMID: 18405323).
Rat reactivity reported in scientific literature (PMID: 25058444)
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Tissue culture supernatant
0.1% Sodium Azide
Tissue culture supernatant
Alternate Names for CD68/SR-D1 Antibody (KP1)
CD68 antigenmacrophage antigen CD68
scavenger receptor class D, member 1
CD68, also known as GP110, LAMP4, and SCARD1, encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissues. CD68 is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and favors binding to lectins through its heavily glycosylated extracellular domain. Furthermore, CD68 has also been found to be a member of the scavenger receptor family, whose main purpose is to clear cellular debris and regulate phagocytosis and macrophage recruitment. Recent studies have investigated the role of tumor related macrophages using CD68 as a probe (PMID: 22931216), as well as their involvement in the progression of other cancers (PMID: 21113139).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Ayari H, Legedz L, Lantelme P et al. Auto-amplification of cortisol actions in human carotid atheroma is linked to arterial remodeling and stroke Fundamental & Clinical Pharmacology 2012 Jul 20 (IHC, Human)
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Review this Product
Be the first to review our CD68/SR-D1 Antibody (KP1) and receive a gift card or discount.