Western Blot: TWEAK R/TNFRSF12 Antibody [NB100-56636] - Analysis of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using this antibody at 1:500.
Western Blot: TWEAK R/TNFRSF12 Antibody [NB100-56636] - Analysis of TweakR in 293 cells. Untransfected (lane 1) or transfectd with human TweakR (lane 2). Photograph courtesy of Dr. Taly Spivakk, The MD Anderson Cancer ...read more
Fibroblast growth factor-inducible immediate-early response protein 14
FN14tumor necrosis factor receptor superfamily member 12A
tumor necrosis factor receptor superfamily, member 12A
type I transmembrane protein Fn14
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines (1, 2). Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library (3). TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.