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1199-TW) inhibits Recombinant Human TWEAK/TNFSF12 (Catalog # 1090-TW) induced proliferation in HUVEC human umbilical vein endothelial cells in a dose-dependent manner (orange line). Inhibition of Recombinant Human TWEAK/TNFSF12 (20 ng/mL) activity elicited by Recombinant Human TWEAK R/TNFRSF12 Fc Chimera (30 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human TWEAK R/TNFRSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1199). The ND50 is typically 0.3-1.2 µg/mL." class="big_lightbox" target="_blank">
1610-TW) was serially diluted and captured by Goat Anti-Mouse TWEAK R/TNFRSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1610) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse TWEAK R/TNFRSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1610) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
1610-TW) was serially diluted and captured by Goat Anti-Mouse TWEAK R/TNFRSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1610) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse TWEAK R/TNFRSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1610) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.
![Immunohistochemistry TWEAK R/TNFRSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/TWEAK_R_AF1610_Immunohistochemistry_6709.jpg)
![ELISA TWEAK R/TNFRSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/af1610_mouse-tweak-r-tnfrsf12-affinity-purified-pab-elisa-639201775314264341.jpg)
![ELISA TWEAK R/TNFRSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/af1610_mouse-tweak-r-tnfrsf12-affinity-purified-pab-elisa-639201856338932667.jpg)
