Transthyretin/Prealbumin Antibody (760430) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clone: 760430
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Transthyretin/Prealbumin Antibody (760430) [Alexa Fluor® 750] Summary

• Immunogen: Human Transthyretin/Prealbumin
• Specificity: Detects human Transthyretin/Prealbumin in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Transthyretin/Prealbumin Antibody (760430) [Alexa Fluor® 750]

• ATTR
• HsT2651
• PALB
• PALBTBPA
• Prealbumin
• prealbumin, amyloidosis type I
• TBPA
• thyroxine-binding prealbumin
• Transthyretin
• TTR

Background

Transthyretin (TTR), previously called thyroxin-binding prealbumin, is a 55 kDa homotetramer of 14-15 kDa monomers that is found in plasma. TTR is responsible for the transport of the thyroid hormone T4 and retinol binding protein (RBP). It slows renal clearance of T4 and RBP due to megalin-mediated re-uptake of TTR complexes in the renal tubules. TTR is also found in tissues including the brain. Numerous human polymorphisms have been associated with aggregates found in familial amyloidotic polyneuropathies (FAP). Mature human TTR shares 80% and 83% amino acid sequence identity with mouse and rat TTR, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.