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Human RBP4 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human RBP4 Quantikine ELISA Kit Summary

Background
The Quantikine Human RBP4 immunoassay is a 2.5 hour solid phase ELISA designed to measure human RBP4 in cell culture supernates, serum, plasma, urine, and saliva. It contains NS0-expressed recombinant human RBP4 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human RBP4 showed linear curves that were parallel to the standard curves obtained ...using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human RBP4.
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Specificity
Natural and recombinant human RBP4
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
RBP4

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DRB400.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human RBP4 Quantikine ELISA Kit

  • interstitial
  • Plasma retinol-binding protein
  • RBP4
  • retinol binding protein 4, plasma
  • RetinolBinding Protein 4
  • retinol-binding protein 4, plasma

Background

Retinol-binding protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum. Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for RBP4/Retinol-Binding Protein 4 (DRB400)(29)

We have publications tested in 2 confirmed species: Human, Mouse.


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Human
(27)
Mouse
(2)
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Showing Publications 1 - 10 of 29. Show All 29 Publications.
Publications using DRB400 Applications Species
Supriya, R;Shishvan, SR;Kefayati, M;Abednatanzi, H;Razi, O;Bagheri, R;Escobar, KA;Pashaei, Z;Saeidi, A;Shahrbanian, S;Bagchi, S;Sengupta, P;Al Kiyumi, MH;Heinrich, KM;Zouhal, H; Astaxanthin Supplementation Augments the Benefits of CrossFit Workouts on Semaphorin 3C and Other Adipokines in Males with Obesity Nutrients 2023-11-16 [PMID: 38004197] (Human) Human
H L?rincz, B Ratku, S Csiha, I Seres, Z Szabó, G Paragh, M Harangi, S Somodi Impaired Organokine Regulation in Non-Diabetic Obese Subjects: Halfway to the Cardiometabolic Danger Zone International Journal of Molecular Sciences, 2023-02-18;24(4):. 2023-02-18 [PMID: 36835525] (Human) Human
H Jeong, AT Armstrong, N Isoherrane, L Czuba, A Yang, K Zumpf, J Ciolino, E Torres, CS Stika, KL Wisner Temporal changes in the systemic concentrations of retinoids in pregnant and postpartum women PLoS ONE, 2023-02-16;18(2):e0280424. 2023-02-16 [PMID: 36795769] (Human) Human
ME Rossholt, K Wendel, M Bratlie, MF Aas, G Gunnarsdot, D Fugelseth, AH Pripp, M Domellöf, K Størdal, T Stiris, SJ Moltu Vitamin A Status in Preterm Infants Is Associated with Inflammation and Dexamethasone Exposure Nutrients, 2023-01-14;15(2):. 2023-01-14 [PMID: 36678312] (Human) Human
N Patel, RR Penkert, RE Sealy, SL Surman, BG Jones, K Ringwald-S, AC Ross, JL Hurwitz Retinol Binding Protein, Sunlight Hours, and the Influenza Virus-Specific Immune Response Biomedicines, 2022-09-19;10(9):. 2022-09-19 [PMID: 36140423] (Human) Human
RR Penkert, M Azul, RE Sealy, BG Jones, J Dowdy, RT Hayden, L Tang, AC Ross, JS Hankins, JL Hurwitz Hypothesis: Low Vitamin A and D Levels Worsen Clinical Outcomes When Children with Sickle Cell Disease Encounter Parvovirus B19 Nutrients, 2022-08-19;14(16):. 2022-08-19 [PMID: 36014920] (Human) Human
N Hirata, M Kiuchi, K Pak, R Fukuda, N Mochimaru, M Mitsui, K Yoshida Association between Maternal Characteristics and Immune Factors TGF-beta1, TGF-beta2, and IgA in Colostrum: An Exploratory Study in Japan Nutrients, 2022-08-09;14(16):. 2022-08-09 [PMID: 36014760] (Human) Human
MM Hasan, MA Gazi, S Das, SM Fahim, F Hossaini, AR Khan, J Ferdous, MA Alam, M Mahfuz, T Ahmed Gut biomolecules (I-FABP, TFF3 and lipocalin-2) are associated with linear growth and biomarkers of environmental enteric dysfunction (EED) in Bangladeshi children Scientific Reports, 2022-08-16;12(1):13905. 2022-08-16 [PMID: 35974137] (Human) Human
LC Czuba, EE Fay, J LaFrance, CK Smith, S Shum, SL Moreni, J Mao, N Isoherrane, MF Hebert Plasma Retinoid Concentrations Are Altered in Pregnant Women Nutrients, 2022-03-25;14(7):. 2022-03-25 [PMID: 35405978] (Human) Human
IL Salazar, AST Lourenço, B Manadas, I Baldeiras, C Ferreira, AC Teixeira, VM Mendes, AM Novo, R Machado, S Batista, MDC Macário, M Grãos, L Sousa, MJ Saraiva, AACC Pais, CB Duarte Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis Journal of Neuroinflammation, 2022-02-08;19(1):44. 2022-02-08 [PMID: 35135578] (Human) Human
Show All 29 Publications.

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Bioinformatics

Gene Symbol RBP4