Human RBP4 Quantikine ELISA Kit



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

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Human RBP4 Quantikine ELISA Kit Summary

The Quantikine Human RBP4 immunoassay is a 2.5 hour solid phase ELISA designed to measure human RBP4 in cell culture supernates, serum, plasma, urine, and saliva. It contains NS0-expressed recombinant human RBP4 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human RBP4 showed linear curves that were parallel to the standard curves obtained ...using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human RBP4.
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Natural and recombinant human RBP4
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DRB400.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human RBP4 Quantikine ELISA Kit

  • interstitial
  • Plasma retinol-binding protein
  • RBP4
  • retinol binding protein 4, plasma
  • RetinolBinding Protein 4
  • retinol-binding protein 4, plasma


Retinol-binding protein 4 (RBP4) is a Lipocalin superfamily molecule that transports vitamin A (retinol) and retinaldehyde in the serum. Retinaldehyde is the critical chromophore in the rhodopsin photoreceptor, while both it and retinoic acid regulate a multitude of cellular differentiation and proliferation effects through the intracellular receptors RAR and RXR. RBP4 is secreted primarily by hepatocytes and adipocytes into the blood where the RBP4-retinol complex interacts with transthyretin (TTR). Formation of the complex with TTR increases the serum half-life of RBP4 by preventing RBP4 filtration through the kidney. The C-terminally processed forms of RBP4, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. RBP4 promotes hyperglycemia, and its upregulation in visceral and liver adipocytes leads to elevated serum levels.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for RBP4/Retinol-Binding Protein 4 (DRB400)(24)

We have publications tested in 2 confirmed species: Human, Mouse.

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Showing Publications 1 - 10 of 24. Show All 24 Publications.
Publications using DRB400 Applications Species
N Patel, RR Penkert, RE Sealy, SL Surman, BG Jones, K Ringwald-S, AC Ross, JL Hurwitz Retinol Binding Protein, Sunlight Hours, and the Influenza Virus-Specific Immune Response Biomedicines, 2022;10(9):. 2022 [PMID: 36140423] (Human) Human
RR Penkert, M Azul, RE Sealy, BG Jones, J Dowdy, RT Hayden, L Tang, AC Ross, JS Hankins, JL Hurwitz Hypothesis: Low Vitamin A and D Levels Worsen Clinical Outcomes When Children with Sickle Cell Disease Encounter Parvovirus B19 Nutrients, 2022;14(16):. 2022 [PMID: 36014920] (Human) Human
N Hirata, M Kiuchi, K Pak, R Fukuda, N Mochimaru, M Mitsui, K Yoshida Association between Maternal Characteristics and Immune Factors TGF-beta1, TGF-beta2, and IgA in Colostrum: An Exploratory Study in Japan Nutrients, 2022;14(16):. 2022 [PMID: 36014760] (Human) Human
LC Czuba, EE Fay, J LaFrance, CK Smith, S Shum, SL Moreni, J Mao, N Isoherrane, MF Hebert Plasma Retinoid Concentrations Are Altered in Pregnant Women Nutrients, 2022;14(7):. 2022 [PMID: 35405978] (Human) Human
IL Salazar, AST Lourenço, B Manadas, I Baldeiras, C Ferreira, AC Teixeira, VM Mendes, AM Novo, R Machado, S Batista, MDC Macário, M Grãos, L Sousa, MJ Saraiva, AACC Pais, CB Duarte Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis Journal of Neuroinflammation, 2022;19(1):44. 2022 [PMID: 35135578] (Human) Human
J Liu, C Nie, L Xue, Y Yan, S Liu, J Sun, M Fan, H Qian, H Ying, L Wang, Y Li Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4 Theranostics, 2021;11(17):8283-8300. 2021 [PMID: 34373742] (Human) Human
Tominaga T, Ikemura T, Yada K, Kanda K, Sugama K, Ma S, Choi W, Araya M, Huang J, Nakamura N, Suzuki K The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males. Antioxidants (Basel), 0;10(6):. 0 [PMID: 34071378] (Human) Human
D Tsakogiann, E Kalogera, F Zagouri, E Zografos, D Balalis, G Bletsa Determination of FABP4, RBP4 and the MMP-9/NGAL complex in the serum of women with breast cancer Oncology Letters, 2021;21(2):85. 2021 [PMID: 33376518] (Human) Human
X Wang, Y Huang, J Gao, H Sun, M Jayachandr, S Qu Changes of serum retinol-binding protein 4 associated with improved insulin resistance after laparoscopic sleeve gastrectomy in Chinese obese patients Diabetol Metab Syndr, 2020;12(0):7. 2020 [PMID: 31956345] (Human) Human
H Wessel, A Saeed, J Heegsma, MA Connelly, KN Faber, RPF Dullaart Plasma Levels of Retinol Binding Protein 4 Relate to Large VLDL and Small LDL Particles in Subjects with and without Type 2 Diabetes J Clin Med, 2019;8(11):. 2019 [PMID: 31717719] (Human) Human
Show All 24 Publications.

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Gene Symbol RBP4