CSRP1 Antibody

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Western blot shows lysates of ME-180 human cervical epithelial carcinoma cell line, HT-2 mouse T cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL Goat ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

CSRP1 Antibody Summary

Immunogen
E. coli-derived recombinant human CSRP1
Met1-Glu193
Accession # P21291
Specificity
Detects human, mouse, and rat CSRP1 in Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CSRP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CSRP1 Antibody

  • CRP
  • CRP1
  • CSRP1
  • CSRPCYRP
  • CYRP
  • cysteine and glycine-rich protein 1
  • Cysteine-rich protein 1
  • D1S181E
  • DKFZp686M148
  • LIM-domain protein

Background

CSRP1 (Cysteine-rich protein 1; also CRP1 and Cysteine and Glycine‑rich protein 1) is a 23 kDa cytoplasmic member of the CRP family of LIM domain‑containing proteins. It is expressed in both visceral and vascular smooth muscle, and interacts with zyxin and alpha ‑actinin, two proteins involved in actin assembly and crosslinking, during muscle cell differentiation. Human CSRP1 is 193 amino acids (aa) in length and contains two 50 aa LIM (for lin11/isl1/mec3) domains that contain two zinc‑finger motifs (aa 10‑61 and 119‑171), an NLS between aa 64‑69, and a Gly-rich C-terminus (aa 176‑187). There are two likely phosphorylation sites at Tyr127 and Ser192. Full‑length human CSRP1 shares 99% aa identity with mouse CSRP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSRP1
Entrez
Uniprot