SOX17 Antibody [Unconjugated]

Western blot shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for SOX17 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Endoderm-differentiated D3 mouse embryonic stem cell line was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX17/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 μL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. The p21 promoter was detected by standard PCR.

Simple Western lane view shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 59 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

SOX17 was detected in immersion fixed B16 mouse melanoma cell line using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counter­stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

SOX17 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Simple Western lane view shows lysates of iBJ6 human induced pluripotent stem cell line untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 58 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

• Reactivity: Hu
• Applications: WB, Simple Western, ChIP, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

SOX17 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human SOX17
  Asp177-Val414
  Accession # Q9H6I2
• Specificity: Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX18 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SOX17
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL
  • Simple Western 10 ug/mL
  • Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells
  • Immunocytochemistry 5-15 ug/mL
• Application Notes: In Simple Western only 10-15 uL of the recommended dilution is used per data point.

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX17 Antibody [Unconjugated]

• FLJ22252
• SOX17
• SRY (sex determining region Y)-box 17
• SRY-related HMG-box transcription factor SOX17
• transcription factor SOX-17
• VUR3

Background

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).

1. Kanai-Azuma, M. et al. (2002) Development 129:2367.
2. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SOX17 Antibody (AF1924)(165)

Publications using AF1924

• S Vallejo-Di, A Fleischer, J María Mart, A Sánchez-Gi, C Gómez-Mart, M Castresana, D Bachiller Generation of one iPSC line (IMEDEAi007-A) by Sendai Virus transduction of PBMCs from a Psoriasis donor Stem Cell Res, 2020;47(0):101917. 2020 [PMID: 32707489] (ICC, Human)
• J Serra-Vina, MB Sandler, E Pak, W Zheng, A Dutra, W Introne, WA Gahl, MC Malicdan Generation and characterization of four Chediak-Higashi Syndrome (CHS) induced pluripotent stem cell (iPSC) lines Stem Cell Res, 2020;47(0):101883. 2020 [PMID: 32619719] (ICC, Human)
• V Meraviglia, CH Arendzen, M Tok, C Freund, AS Maione, E Sommariva, M Bellin Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation Stem Cell Res, 2020;46(0):101835. 2020 [PMID: 32485643] (ICC, Human)
• N Drick, J Dahlmann, A Sahabian, A Haase, G Göhring, N Lachmann, FC Ringshause, T Welte, U Martin, R Olmer Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915C�>�T [p.Arg2639*]) in the DNAH5 gene Stem Cell Res, 2020;46(0):101848. 2020 [PMID: 32470793] (ICC, Human)
• J Dahlmann, A Sahabian, N Drick, A Haase, G Göhring, N Lachmann, FC Ringshause, T Welte, U Martin, R Olmer Generation of two hiPSC lines (MHHi016-A, MHHi016-B) from a primary ciliary dyskinesia patient carrying a homozygous 5�bp duplication (c.248_252dup (p.Gly85Cysfs*11)) in exon 1 of the CCNO gene Stem Cell Res, 2020;46(0):101850. 2020 [PMID: 32464346] (Flow Cytometry, Human)
• Y Nakatake, SBH Ko, AA Sharov, S Wakabayash, M Murakami, M Sakota, N Chikazawa, C Ookura, S Sato, N Ito, M Ishikawa-H, SS Mak, LM Jakt, T Ueno, K Hiratsuka, M Matsushita, SK Goparaju, T Akiyama, KI Ishiguro, M Oda, N Gouda, A Umezawa, H Akutsu, K Nishimura, R Matoba, O Ohara, MSH Ko Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors Cell Rep, 2020;31(7):107655. 2020 [PMID: 32433964] (ICC, Human)
• Y Ueda, C Kimura-Yos, K Mochida, M Tsume, Y Kameo, T Adachi, O Lefebvre, R Hiramatsu, I Matsuo Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis Cell Rep, 2020;31(7):107637. 2020 [PMID: 32433954] (IHC, Mouse)
• K Kamata, Y Otsuka, K Imamura, A Oishi, T Kondo, M Suga, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Yasukawa, H Usui, K Muguruma, A Tsujikawa, H Inoue Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration Stem Cell Res, 2020;45(0):101787. 2020 [PMID: 32416577] (ICC, Human)
• K Kamata, Y Otsuka, K Imamura, A Oishi, T Kondo, M Suga, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Yasukawa, H Usui, K Muguruma, A Tsujikawa, H Inoue Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations Stem Cell Res, 2020;45(0):101782. 2020 [PMID: 32416576] (ICC, Human)
• H Suzuki, N Egawa, T Kondo, K Imamura, T Enami, K Tsukita, M Suga, R Shibukawa, Y Okanishi, T Uchiyama, H Inoue, R Takahashi Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication Stem Cell Res, 2020;45(0):101828. 2020 [PMID: 32413791] (Flow Cytometry, Human)
• M Tariq, H Liu, DP Ibañez, Y Li, S Chen, M Jiang, W Fan, P Zhao, Z Luo, D Wang, S Kanwal Generation of three induced pluripotent stem cell lines from a Parkinson's disease patient with mutant PARKIN�(p. C253Y) Stem Cell Res, 2020;45(0):101822. 2020 [PMID: 32387897] (Functional Assay, Human)
• A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation Mol Ther Methods Clin Dev, 2020;17(0):858-870. 2020 [PMID: 32373648] (ICC, Human)
• V Meraviglia, CH Arendzen, C Freund, DE Atsma, CL Mummery, M Bellin Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene Stem Cell Res, 2020;45(0):101764. 2020 [PMID: 32315959] (ICC, Human)
• M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation Stem Cell Res, 2020;45(0):101781. 2020 [PMID: 32305865] (ICC, Human)
• S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi Generation of intestinal organoids derived from human pluripotent stem cells for drug testing Sci Rep, 2020;10(1):5989. 2020 [PMID: 32249832] (ICC, Human)
• M Uemura, M Higashi, M Pattarapan, S Takami, N Ichikawa, H Higashiyam, T Furukawa, J Fujishiro, Y Fukumura, T Yao, T Tajiri, M Kanai-Azum, Y Kanai Gallbladder wall abnormality in biliary atresia of mouse Sox17+/- neonates and human infants Dis Model Mech, 2020;13(4):. 2020 [PMID: 31996362] (IHC, Human)
• J Choi, BJ Seo, H La, SH Yoon, YJ Hong, JH Lee, HM Chung, K Hong, JT Do Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells Redox Biol, 2020;30(0):101437. 2020 [PMID: 31981893] (ICC, Human)
• A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids Nat. Cell Biol., 2020;22(1):60-73. 2020 [PMID: 31907413] (IF, Mouse)
• JR Alvarez-Do, J Donaghey, N Rasouli, JHR Kenty, A Helman, J Charlton, JR Straubhaar, A Meissner, DA Melton Circadian Entrainment Triggers Maturation of Human In�Vitro Islets Cell Stem Cell, 2019;26(1):108-122.e10. 2019 [PMID: 31839570] (ICC, Human)
• DM Barry, EA McMillan, B Kunar, R Lis, T Zhang, T Lu, E Daniel, M Yokoyama, JM Gomez-Sali, A Sureshbabu, O Cleaver, A Di Lorenzo, ME Choi, J Xiang, D Redmond, SY Rabbany, T Muthukumar, S Rafii Molecular determinants of nephron vascular specialization in the kidney Nat Commun, 2019;10(1):5705. 2019 [PMID: 31836710] (IHC, Mouse)
• N Drick, A Sahabian, P Pongpamorn, S Merkert, G Göhring, T Welte, U Martin, R Olmer Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4) Stem Cell Res, 2019;42(0):101659. 2019 [PMID: 31791010] (ICC, Human)
• M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations Stem Cell Res, 2019;42(0):101657. 2019 [PMID: 31786474] (ICC, Human)
• A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation Nat Commun, 2019;10(1):5462. 2019 [PMID: 31784515] (ICC, Mouse)
• MM Abdul, DP Ibañez, P Zhao, H Liu, X Zhong, Y Li, M Zhang, W Li, Y Li, C Ward, S Chen, D Wang, B Qin, MA Esteban, X Wang, W Fan, Z Luo Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N) Stem Cell Res, 2019;41(0):101607. 2019 [PMID: 31778937] (ICC, Human)
• L Xie, J Huang, X Li, L Dai, X Lin, J Zhang, J Luo, W Zhang Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing Stem Cell Res, 2019;41(0):101610. 2019 [PMID: 31775087] (ICC, Human)
• SY Lee, SK Chung Generation of gene-corrected iPSC line, KIOMi002-A, from Parkinson's disease patient iPSC with LRRK2 G2019S mutation using BAC-based homologous recombination Stem Cell Res, 2019;41(0):101649. 2019 [PMID: 31731184] (ICC, Human)
• N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency Stem Cell Reports, 2019;13(6):1083-1098. 2019 [PMID: 31708477] (ICC, Human)
• J Frew, X Wu, GY Hsiung, HH Feldman, IR Mackenzie, HB Nygaard Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation Stem Cell Res, 2019;41(0):101582. 2019 [PMID: 31707213] (ICC, Human)
• C Lu, NE Sanjana Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A) Stem Cell Res, 2019;41(0):101643. 2019 [PMID: 31707212] (ICC, Human)
• BJ Seo, HS Jang, H Song, C Park, K Hong, JW Lee, JT Do Generation of Mouse Parthenogenetic Epiblast Stem Cells and Their Imprinting Patterns Int J Mol Sci, 2019;20(21):. 2019 [PMID: 31683583] (ICC, Mouse)
• AJ Duarte, D Ribeiro, R Santos, L Moreira, J Bragança, O Amaral Induced pluripotent stem cell line (INSAi001-A) from a Gaucher disease type 3 patient compound heterozygote for mutations in the GBA1 gene Stem Cell Res, 2019;41(0):101595. 2019 [PMID: 31678773] (ICC, Human)
• S Kinnear, LA Salamonsen, M Francois, V Harley, J Evans Uterine SOX17: a key player in human endometrial receptivity and embryo implantation Sci Rep, 2019;9(1):15495. 2019 [PMID: 31664088] (IHC, Human)
• S Chhabra, L Liu, R Goh, X Kong, A Warmflash Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids PLoS Biol., 2019;17(10):e3000498. 2019 [PMID: 31613879] (ICC, Human)
• Q Li, Q Huang Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition PLoS ONE, 2019;14(10):e0223724. 2019 [PMID: 31600351] (ICC, Human)
• V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure Nat Commun, 2019;10(1):4161. 2019 [PMID: 31551422] (ICC, Human)
• F Tonon, GG Giobbe, A Zambon, C Luni, O Gagliano, A Floreani, G Grassi, N Elvassore In vitro metabolic zonation through oxygen gradient on a chip Sci Rep, 2019;9(1):13557. 2019 [PMID: 31537830] (ICC, Human)
• MT De Angelis, G Santamaria, EI Parrotta, S Scalise, M Lo Conte, S Gasparini, E Ferlazzo, U Aguglia, C Ciampi, A Sgura, G Cuda Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus J. Cell. Mol. Med., 2019;0(0):. 2019 [PMID: 31536674] (ICC, Human)
• S Yoshimatsu, T Sone, M Nakajima, T Sato, R Okochi, M Ishikawa, M Nakamura, E Sasaki, S Shiozawa, H Okano A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology PLoS ONE, 2019;14(8):e0221164. 2019 [PMID: 31454364] (ICC, Human)
• HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes Stem Cells, 2019;0(0):. 2019 [PMID: 31348575] (Western Blot, Human)
• S Payne, M Gunadasa-R, A Neal, AN Redpath, J Patel, KM Chouliaras, I Ratnayaka, N Smart, S De Val Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart Nat Commun, 2019;10(1):3276. 2019 [PMID: 31332177] (IHC-Fr, Mouse)
• A Perea-Gome, O Cases, V Lelièvre, MV Pulina, J Collignon, AK Hadjantona, R Kozyraki Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse Sci Rep, 2019;9(1):10168. 2019 [PMID: 31308417] (IHC, Mouse)
• S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line Stem Cell Res, 2019;38(0):101453. 2019 [PMID: 31082677] (ICC, Human)
• H Hosseini F, YN Patria, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing Stem Cell Res, 2019;37(0):101449. 2019 [PMID: 31075690] (ICC, Human)
• S Ross, M Holliday, S Lim, C Semsarian Characterization of the first induced pluripotent stem cell line generated from a patient with autosomal dominant catecholaminergic polymorphic ventricular tachycardia due to a heterozygous mutation in cardiac calsequestrin-2 Stem Cell Res, 2019;37(0):101450. 2019 [PMID: 31039485] (ICC, Human)
• T Minami, T Ishii, K Yasuchika, K Fukumitsu, S Ogiso, Y Miyauchi, H Kojima, T Kawai, R Yamaoka, Y Oshima, H Kawamoto, M Kotaka, K Yasuda, K Osafune, S Uemoto Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold Regen Ther, 2019;10(0):127-133. 2019 [PMID: 31032388] (ICC, Human)
• S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, M Castresana, D Aguillón, A Villegas, CA Mastronard, LG Espinosa, M Arcos-Burg, Á Del Pozo, E Herrán, E Gainza, M Isaza-Ruge, F Lopera, D Bachiller Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene Stem Cell Res, 2019;37(0):101440. 2019 [PMID: 31026686] (ICC, Human)
• RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development Cell Rep, 2019;27(3):708-718.e10. 2019 [PMID: 30995470] (ICC, Human)
• WK Au Yeung, J Brind'Amou, Y Hatano, K Yamagata, R Feil, MC Lorincz, M Tachibana, Y Shinkai, H Sasaki Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection Cell Rep, 2019;27(1):282-293.e4. 2019 [PMID: 30943408] (IHC, Mouse)
• M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I Stem Cell Res, 2019;36(0):101406. 2019 [PMID: 30849633] (ICC, Human)
• U Diekmann, H Wolling, R Dettmer, I Niwolik, O Naujok, FFR Buettner Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture Sci Rep, 2019;9(1):996. 2019 [PMID: 30700818] (ICC, Human)
• X Wang, T Liao, C Wan, X Yang, J Zhao, R Fu, Z Yao, Y Huang, Y Shi, G Chang, Y Zheng, F Luo, Z Liu, Y Wang, X Mao, XY Zhao Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale PeerJ, 2019;6(0):e6143. 2019 [PMID: 30643676] (IHC-Fr, Human)
• JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene Stem Cell Res, 2018;34(0):101361. 2018 [PMID: 30611021] (ICC, Human)
• W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, G Wu, Z Zhu, Y Yu, L Yu, J Choudhary, J Nichols, MM Parast, B Greber, P Sahlén, K Plath The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation Cell Stem Cell, 2019;24(1):138-152.e8. 2019 [PMID: 30609396] (Western Blot, Mouse)
• S Schuster, S Saravanaku, L Schöls, S Hauser Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus Stem Cell Res, 2018;34(0):101378. 2018 [PMID: 30605842] (ICC, Human)
• S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JC Kuo, JP Derks, VS Akhade, Y Kargapolov, T Georgomano, JE Messling, M Gramm, L Brant, R Rehimi, NE Vargas, A Kuroczik, TP Yang, RGA Sahito, J Franzen, J Hescheler, A Sachinidis, M Peifer, A Rada-Igles, M Kanduri, IG Costa, C Kanduri, A Papantonis, L Kurian yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs Cell Stem Cell, 2018;0(0):. 2018 [PMID: 30554961] (ICC, Mouse)
• Baulier E, Garcia Diaz A, Corneo B, Farber D Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143. Stem Cell Res, 0;33(0):274-277. 0 [PMID: 30513407] (Bioassay, Human)
• TR Broda, KW McCracken, JM Wells Generation of human antral and fundic gastric organoids from pluripotent stem cells Nat Protoc, 2019;14(1):28-50. 2019 [PMID: 30470820] (ICC, Human)
• T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badi, S Mukherjee, Z Ghazizadeh, H Zeng, M Guo, M Crespo, T Zhang, R Kenyon, CL Robinson, E Apostolou, H Wang, JZ Xiang, T Evans, L Studer, S Chen A hPSC-based platform to discover gene-environment interactions that impact human ?-cell and dopamine neuron survival Nat Commun, 2018;9(1):4815. 2018 [PMID: 30446643] (ICC, Human)
• S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient Stem Cell Res, 2018;33(0):180-184. 2018 [PMID: 30408744] (ICC, Human)
• X Wang, X Li, T Wang, SP Wu, JW Jeong, TH Kim, SL Young, BA Lessey, RB Lanz, JP Lydon, FJ DeMayo SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh Nat Commun, 2018;9(1):4421. 2018 [PMID: 30356064] (Immunoprecipitation, Mouse)
• M Holliday, SB Ross, S Lim, C Semsarian Generation of an induced pluripotent stem cell line from a hypertrophic cardiomyopathy patient with a pathogenic myosin binding protein C (MYBPC3) p.Arg502Trp mutation Stem Cell Res, 2018;33(0):56-59. 2018 [PMID: 30316040] (ICC, Human)
• A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids Elife, 2018;7(0):. 2018 [PMID: 30311909] (ICC, Human)
• S Vallejo, A Fleischer, JM Martín, A Sánchez, E Palomino, D Bachiller Generation of two induced pluripotent stem cells lines from Mucopolysaccharydosis IIIA patient: IMEDEAi004-A and IMEDEAi004-B Stem Cell Res, 2018;32(0):110-114. 2018 [PMID: 30269021] (Human)
• Y Arioka, I Kushima, D Mori, N Ozaki Three lines of induced pluripotent stem cells derived from a 15q11.2-q13.1 duplication syndrome patient Stem Cell Res, 2018;31(0):240-243. 2018 [PMID: 30144654] (IHC, Human)
• R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata) Sci Rep, 2018;8(1):12187. 2018 [PMID: 30111816] (ICC, Primate - Macaca mulatta (Rhesus Macaque))
• X Gao, JJ Yourick, RL Sprando Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel Stem Cell Res, 2018;31(0):193-196. 2018 [PMID: 30099336] (ICC, Human)
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Reviews for SOX17 Antibody (AF1924) (3)

Average Rating: 4.7

(Based on 3 reviews)

We have 3 reviews tested in 2 species: Human, Other.

reviewed by: Anonymous IF Human 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 23658023
• Species: Human

Blocking

• Blocking Details: See PMIC 23658023

Details

• Detection Notes: See PMIC 23658023

Comments

• Comments: Published: See PMIC 23658023

reviewed by: Anonymous IF Human 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 22613812
• Species: Human

Blocking

• Blocking Details: See PMIC 22613812

Details

• Detection Notes: See PMIC 22613812

Comments

• Comments: Published: See PMIC 22613812

reviewed by: Anonymous IF Other 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 23418163
• Species: Other

Blocking

• Blocking Details: See PMIC 23418163

Details

• Detection Notes: See PMIC 23418163

Comments

• Comments: Published: See PMIC 23418163

Bioinformatics

• Gene Symbol: SOX17
• Uniprot:
  • Q9H6I2()