SOX17 Antibody [Unconjugated]

Western blot shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for SOX17 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Endoderm-differentiated D3 mouse embryonic stem cell line was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX17/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 μL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. The p21 promoter was detected by standard PCR.

SOX17 was detected in immersion fixed B16 mouse melanoma cell line using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counter­stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

SOX17 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Simple Western lane view shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 59 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Simple Western lane view shows lysates of iBJ6 human induced pluripotent stem cell line untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 58 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

• Reactivity: Hu
• Applications: WB, Simple Western, ChIP, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

SOX17 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human SOX17
  Asp177-Val414
  Accession # Q9H6I2
• Specificity: Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX18 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SOX17
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells
  • Immunocytochemistry 5-15 ug/mL
  • Simple Western 10 ug/mL
  • Western Blot 1 ug/mL
• Application Notes: In Simple Western only 10-15 uL of the recommended dilution is used per data point.

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX17 Antibody [Unconjugated]

• FLJ22252
• SOX17
• SRY (sex determining region Y)-box 17
• SRY-related HMG-box transcription factor SOX17
• transcription factor SOX-17
• VUR3

Background

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).

1. Kanai-Azuma, M. et al. (2002) Development 129:2367.
2. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SOX17 Antibody (AF1924)(275)

Publications using AF1924

• A Uchida, K Imaimatsu, H Suzuki, X Han, H Ushioda, M Uemura, K Imura-Kish, R Hiramatsu, HM Takase, Y Hirate, A Ogura, M Kanai-Azum, A Kudo, Y Kanai SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse Nature Communications, 2022;13(1):7860. 2022 [PMID: 36543770] (IHC, Mouse)
• D Shang, T Lan, Y Wang, X Li, Q Liu, H Dong, B Xu, H Cheng, R Zhou PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders Cell & bioscience, 2022;12(1):194. 2022 [PMID: 36457060] (IHC/IF, Human)
• DC Miller, P Lisowski, S Lickfett, B Mlody, M Bünning, C Genehr, C Ulrich, EE Wanker, S Diecke, J Priller, A Prigione Generation of induced pluripotent stem cells from three individuals with Huntington's disease Stem Cell Research, 2022;65(0):102976. 2022 [PMID: 36434993] (Flow Cytometry, Human)
• JH Song, J Choi, YJ Hong, H La, TK Hong, K Hong, JT Do Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming Cells, 2022;11(20):. 2022 [PMID: 36291134] (ICC, Mouse)
• MC Jaboreck, JL Lühmann, M Mielenz, F Stanke, G Göhring, U Martin, R Olmer, S Merkert Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line Stem Cell Research, 2022;64(0):102918. 2022 [PMID: 36162332] (IHC, Human)
• T Steiner, A Zink, MT Henke, G Cecchetto, M Buenning, A Rossi, M Schuelke, A Prigione RNA-based generation of iPSCs from a boy carrying the mutation m.9185�T>C in the mitochondrial gene MT-ATP6 and from his healthy mother Stem Cell Research, 2022;64(0):102920. 2022 [PMID: 36137325] (IHC, Human)
• H Tomita, KM Hines, JM Herron, A Li, DW Baggett, L Xu 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome Elife, 2022;11(0):. 2022 [PMID: 36111785] (IHC, Mouse)
• TXA Pham, A Panda, H Kagawa, SK To, C Ertekin, G Georgolopo, SSFA van Knippe, RN Allsop, A Bruneau, JS Chui, L Vanheer, A Janiszewsk, J Chappell, M Oberhuemer, RS Tchinda, I Talon, S Khodeer, J Rossant, F Lluis, L David, N Rivron, BP Balaton, V Pasque Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells Cell Stem Cell, 2022;29(9):1346-1365.e10. 2022 [PMID: 36055191] (ICC, Human)
• S Mukherjee, DM Luedeke, L McCoy, M Iwafuchi, AM Zorn SOX transcription factors direct TCF-independent WNT/beta-catenin responsive transcription to govern cell fate in human pluripotent stem cells Cell Reports, 2022;40(8):111247. 2022 [PMID: 36001974] (Western Blot, Human)
• M Alonzo, J Contreras, S Ye, H Lin, L Hernandez-, KL McBride, K Texter, V Garg, MT Zhao Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS) Stem Cell Research, 2022;64(0):102892. 2022 [PMID: 35987121] (Flow Cytometry, Human)
• J Contreras, M Alonzo, S Ye, H Lin, L Hernandez-, KL McBride, K Texter, V Garg, MT Zhao Generation of an induced pluripotent stem cell line NCHi003-A from a 11-year-old male with pulmonary atresia with intact ventricular septum (PA-IVS) Stem Cell Research, 2022;64(0):102893. 2022 [PMID: 35987120] (Flow Cytometry, Human)
• Z Jiang, XJ Gu, WM Su, QQ Duan, JY Lin, B Cao, HF Shang, YP Chen Production of a human iPSC line from an early-onset Parkinson's disease patient with a novel CHCHD2 gene truncated mutation Stem Cell Research, 2022;64(0):102881. 2022 [PMID: 35944313] (Flow Cytometry, Human)
• H Okumura, Y Arioka, I Kushima, D Mori, N Ozaki Establishment of induced pluripotent stem cells from a patient with 16p13.11 duplication and VPS13B deletion Stem Cell Research, 2022;64(0):102884. 2022 [PMID: 35944312] (Flow Cytometry, Human)
• J Liu, GC Black, SJ Kimber, PI Sergouniot Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing Stem Cell Research, 2022;64(0):102880. 2022 [PMID: 35933957] (Flow Cytometry, Human)
• JJ Thompson, DJ Lee, A Mitra, S Frail, RK Dale, PP Rocha Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages Nature Communications, 2022;13(1):4257. 2022 [PMID: 35871075] (IHC, Mouse)
• Y Sun, J Fu, J Yang, J Zhao, J Rong Generation of a RRAGA knockout human iPSC line GIBHi002-A-5 using CRISPR/Cas9 technology Oncogene, 2022;63(0):102859. 2022 [PMID: 35870248] (Flow Cytometry, Human)
• EZ Sim, T Enomoto, N Shiraki, N Furuta, S Kashio, T Kambe, T Tsuyama, A Arakawa, H Ozawa, M Yokoyama, M Miura, S Kume Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization Cell Reports, 2022;40(3):111120. 2022 [PMID: 35858556] (ICC, Human)
• Y Shi, S Wu, B Yang, B Yu, Y Yan, J Yang, M Chu, X Hu Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus Stem Cell Research, 2022;62(0):102801. 2022 [PMID: 35609349] (ICC, Human)
• WS Fagg, N Liu, U Braunschwe, KL Pereira de, X Chen, FS Ditmars, SG Widen, JP Donohue, K Modis, WK Russell, JH Fair, MT Weirauch, BJ Blencowe, MA Garcia-Bla Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate Nucleic Acids Research, 2022;50(9):5313-5334. 2022 [PMID: 35544276] (Western Blot, Human)
• F Papes, AP Camargo, JS de Souza, VMA Carvalho, RA Szeto, E LaMontagne, JR Teixeira, SH Avansini, SM Sánchez-Sá, TS Nakahara, CN Santo, W Wu, H Yao, BMP Araújo, PENF Velho, GG Haddad, AR Muotri Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content Nature Communications, 2022;13(1):2387. 2022 [PMID: 35501322] (IHC, Human)
• J Jeong, TH Kim, M Kim, YK Jung, KS Kim, S Shim, H Jang, WI Jang, SB Lee, D Choi Elimination of Reprogramming Transgenes Facilitates the Differentiation of Induced Pluripotent Stem Cells into Hepatocyte-like Cells and Hepatic Organoids Biology, 2022;11(4):. 2022 [PMID: 35453693] (ICC, Human)
• HM Lee, AH Kim, S Hwang, J Jung, H Seol, JJ Sung, SM Jeong, YM Choi, JK Jun, HS Kim, J Jang Generation of alphaMHC-EGFP knock-in in human pluripotent stem cell line, SNUe003-A-3 using CRISPR/Cas9-based gene targeting Stem Cell Research, 2022;61(0):102779. 2022 [PMID: 35427904] (ICC, Human)
• A Manhas, JWS Jahng, CD Vera, SP Shenoy, JW Knowles, JC Wu Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants Stem Cell Research, 2022;61(0):102774. 2022 [PMID: 35413566] (ICC, Human)
• X Hu, S Xiong, X Zhou, L Sun Generation of a human induced pluripotent stem cell line FMUPDCi001-A from a patient with mental retardation, autosomal recessive 36 (MRT36) carrying the variants c.219dupA and c.587C�>�T in ADAT3 Stem Cell Research, 2022;61(0):102777. 2022 [PMID: 35405382] (ICC, Human)
• M Breyer, T Klein, K Klug, E Klopocki, N Üçeyler Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease Stem Cell Research, 2022;61(0):102747. 2022 [PMID: 35325818] (ICC, Human)
• C Lorenz, A Zink, MT Henke, S Staege, B Mlody, M Bünning, E Wanker, S Diecke, M Schuelke, A Prigione Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T�>�G or m.8993T�>�C in the mitochondrial gene MT-ATP6 Stem Cell Research, 2022;61(0):102742. 2022 [PMID: 35279592] (ICC, Human)
• W Chiu, A Li, T Wang, W Li, X Zhang Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology Stem Cell Research, 2022;60(0):102729. 2022 [PMID: 35247841] (ICC, Human)
• C Royer, E Sandham, E Slee, F Schneider, CB Lagerholm, J Godwin, N Veits, H Hathrell, F Zhou, K Leonaviciu, J Garratt, T Narendra, A Vincent, C Jones, T Child, K Coward, C Graham, M Fritzsche, X Lu, S Srinivas ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis Nature Communications, 2022;13(1):941. 2022 [PMID: 35177595] (IHC, Mouse)
• D Han, G Wu, R Chen, HCA Drexler, CM MacCarthy, KP Kim, K Adachi, D Gerovska, L Mavrommati, I Bedzhov, MJ Araúzo-Bra, HR Schöler A balanced Oct4 interactome is crucial for maintaining pluripotency Science Advances, 2022;8(7):eabe4375. 2022 [PMID: 35171666] (ICC, Human)
• T Pock, K Schulte, S Schlatt, M Boiani, V Nordhoff GM-CSF perturbs cell identity in mouse pre-implantation embryos PLoS ONE, 2022;17(2):e0263793. 2022 [PMID: 35143564] (IHC, Mouse)
• S Chumchuen, C Satirapod, A Tangprasit, S Hongeng Establishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts Stem Cell Research, 2022;60(0):102675. 2022 [PMID: 35114587] (ICC, Human)
• OH Lee, S Lee, M Park, S Moon, S Hwang, B Kim, CY Kim, DR Lee, SH Shim, KH Park, HM Chung, Y Choi Generation of a B2M homozygous knockout human somatic cell nuclear transfer-derived embryonic stem cell line using the CRISPR/Cas9 system Stem Cell Research, 2021;59(0):102643. 2021 [PMID: 34971932] (Flow Cytometry, Human)
• C Lee, S Cho, C Lai, S Shenoy, R Vagelos, JC Wu Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant Stem Cell Research, 2021;59(0):102638. 2021 [PMID: 34954454] (Flow Cytometry, Human)
• L Taher, S Israel, HCA Drexler, W Makalowski, Y Suzuki, G Fuellen, M Boiani The proteome, not the transcriptome, predicts that oocyte superovulation affects embryonic phenotypes in mice Scientific Reports, 2021;11(1):23731. 2021 [PMID: 34887460] (IHC, Mouse)
• Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, O Elemento, S Chen, D Huangfu, T Evans Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation Cell Reports, 2021;37(10):110095. 2021 [PMID: 34879277] (Western Blot, Human)
• N Belbachir, C Lai, JW Rhee, Y Zhuge, MV Perez, K Sallam, JC Wu Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations Stem Cell Research, 2021;57(0):102605. 2021 [PMID: 34856468] (Flow Cytometry, Human)
• M Liu, N Ge, Y Han, J Reilly, M Yang, F Yang, J Krawczyk, V McInerney, T O'Brien, T Prendivill, S Shen Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual Stem Cell Research, 2021;57(0):102607. 2021 [PMID: 34844101] (ICC, Human)
• AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients Cells, 2021;10(11):. 2021 [PMID: 34831322] (ICC, Human)
• C Völkner, M Liedtke, R Untucht, A Hermann, MJ Frech Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease International Journal of Molecular Sciences, 2021;22(22):. 2021 [PMID: 34830064] (ICC, Human)
• S Jalil, T Keskinen, R Maldonado, J Sokka, R Trokovic, T Otonkoski, K Wartiovaar Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts Stem Cell Reports, 2021;0(0):. 2021 [PMID: 34822772] (IHC, Human)
• RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandrat, DA Roberts, J Wang, S Kefalopoul, A Ramirez, Y Qiu, J Chiou, KJ Gaulton, B Ren, DN Kotton, M Sander Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Nature Communications, 2021;12(1):6636. 2021 [PMID: 34789735] (IHC, Human)
• S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas Science Advances, 2021;7(47):eabj0512. 2021 [PMID: 34788095] (IHC, Mouse)
• L Drakhlis, SB Devadas, R Zweigerdt Generation of heart-forming organoids from human pluripotent stem cells Nature Protocols, 2021;0(0):. 2021 [PMID: 34759383] (IHC, Human)
• JR Valcourt, RE Huang, S Kundu, D Venkatasub, RE Kingston, S Ramanathan Modulating mesendoderm competence during human germ layer differentiation Cell Reports, 2021;37(6):109990. 2021 [PMID: 34758327] (IF, Human)
• E Sintov, D Gerace, DA Melton A human ESC line for efficient CRISPR editing of pluripotent stem cells Stem Cell Research, 2021;57(0):102591. 2021 [PMID: 34741877] (Flow Cytometry, Human)
• K Krawczyk, E Kosyl, K Cz??cik-?y, T Wyszomirsk, M Maleszewsk Developmental capacity is unevenly distributed among single blastomeres of 2-cell and 4-cell stage mouse embryos Scientific Reports, 2021;11(1):21422. 2021 [PMID: 34728646] (IHC, Mouse)
• S Ding, X Lan, Y Meng, C Yan, M Li, X Li, J Chen, W Jiang CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis Cell Death & Disease, 2021;12(11):981. 2021 [PMID: 34686651] (ICC, Human)
• HC Ting, HI Yang, HJ Harn, IM Chiu, HL Su, X Li, MF Chen, TJ Ho, CA Liu, YJ Tsai, TW Chiou, SZ Lin, CY Chang Coactivation of GSK3beta and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons Cells, 2021;10(10):. 2021 [PMID: 34685754] (ICC, Human)
• L Scaramuzzi, V Lucchino, S Scalise, M Lo Conte, C Zannino, A Sacco, F Biamonte, EI Parrotta, FS Costanzo, G Cuda Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing Cells, 2021;10(9):. 2021 [PMID: 34572080] (ICC, Human)
• T Bluhmki, S Traub, AK Müller, S Bitzer, E Schruf, MT Bammert, M Leist, F Gantner, JP Garnett, R Heilker Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model Scientific Reports, 2021;11(1):17028. 2021 [PMID: 34426605] (IHC, Human)
• Y Shamshirga, A Jonebring, A Svensson, I Leefa, M Bohlooly-Y, M Firth, KJ Woollard, A Hofherr, IM Rogers, R Hicks Rapid target validation in a Cas9-inducible hiPSC derived kidney model Scientific Reports, 2021;11(1):16532. 2021 [PMID: 34400685] (IHC, Human)
• A Usman, A Haase, S Merkert, G Göhring, G Hansmann, H Gall, R Schermuly, U Martin, R Olmer Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in exon 11 of the BMPR2 gene Stem Cell Research, 2021;55(0):102488. 2021 [PMID: 34388490] (IHC, Human)
• B Li, C Qiao, X Jin, HM Chan Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells Environmental health perspectives, 2021;129(7):77007. 2021 [PMID: 34328791] (Western Blot, Human)
• BC Liu, FY Liu, XY Gao, YL Chen, QQ Meng, YL Song, XH Li, SQ Bao Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells International Journal of Molecular Sciences, 2021;22(14):. 2021 [PMID: 34299091] (ICC, Human)
• L Ma, M Schmidt, EM Morrow Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls Stem Cell Research, 2021;54(0):102435. 2021 [PMID: 34182254] (ICC, Human)
• PJ Houweling, CA Coles, CF Tiong, B Nielsen, A Graham, P McDonald, A Suter, AT Piers, R Forbes, MM Ryan, SE Howden, SR Lamandé, KN North Generating an iPSC line (with isogenic control) from the PBMCs of an ACTA1 (p.Gly148Asp) nemaline myopathy patient Stem Cell Research, 2021;54(0):102429. 2021 [PMID: 34157503] (Flow Cytometry, Human)
• N Ge, M Liu, X Zhu, J Krawczyk, V McInerney, S Shen, T O'Brien, T Prendivill Generation and characterization of three induced pluripotent stem cell lines (NUIGi047-A, NUIGi047-B, NUIGi047-C) from a 7-year-old healthy Caucasian male Stem Cell Research, 2021;53(0):102389. 2021 [PMID: 34088016] (ICC, Human)
• S Yoshimatsu, E Qian, T Sato, M Yamamoto, M Ishikawa, H Okano Establishing an induced pluripotent stem cell line from neonatal common marmoset fibroblasts by an all-in-one episomal vector approach Stem Cell Research, 2021;53(0):102380. 2021 [PMID: 34088009] (ICC, Marmoset)
• S Yoshimatsu, K Edamura, Y Yoshii, A Iguchi, H Kondo, H Shibuya, T Sato, S Shiozawa, H Okano Non-viral derivation of a transgene-free induced pluripotent stem cell line from a male beagle dog Stem Cell Research, 2021;53(0):102375. 2021 [PMID: 34088004] (ICC, Canine)
• D Gerace, KR Boulanger, J Hyoje-Ryu, DA Melton Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny Stem Cell Research, 2021;53(0):102371. 2021 [PMID: 34088000] (Flow Cytometry, Human)
• DJ Truong, T Phlairahar, B E beta wein, C Gruber, D Tümen, E Baligács, N Armbrust, FL Vaccaro, EM Lederer, EM Beck, J Geilenkeus, S Göppert, L Krumwiede, C Grätz, G Raffl, D Schwarz, M Zirngibl, M Živani?, M Beyer, JD Körner, T Santl, V Evsyukov, T Strau beta , SC Schwarz, GU Höglinger, P Heutink, S Doll, M Conrad, F Giesert, W Wurst, GG Westmeyer Non-invasive and high-throughput interrogation of exon-specific isoform expression Nature Cell Biology, 2021;23(6):652-663. 2021 [PMID: 34083785] (ICC, Human)
• PF Xu, RM Borges, J Fillatre, M de Oliveir, T Cheng, B Thisse, C Thisse Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre Nature Communications, 2021;12(1):3277. 2021 [PMID: 34078907] (IHC, Mouse)
• D Meisterman, A Bruneau, S Loubersac, A Reignier, J Firmin, V François-C, S Kilens, Y Lelièvre, J Lammers, M Feyeux, P Hulin, S Nedellec, B Bretin, G Castel, N Allègre, S Covin, A Bihouée, M Soumillon, T Mikkelsen, P Barrière, C Chazaud, J Chappell, V Pasque, J Bourdon, T Fréour, L David Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification Cell Stem Cell, 2021;0(0):. 2021 [PMID: 34004179] (IHC, Human)
• A Yanagida, D Spindlow, J Nichols, A Dattani, A Smith, G Guo Naive stem cell blastocyst model captures human embryo lineage segregation Cell Stem Cell, 2021;28(6):1016-1022.e4. 2021 [PMID: 33957081] (ICC, Human)
• J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna Principles of signaling pathway modulation for enhancing human naive pluripotency induction Cell Stem Cell, 2021;0(0):. 2021 [PMID: 33915080] (IHC, Mouse)
• DJ Sutcliffe, AR Dinasarapu, JE Visser, JD Hoed, F Seifar, P Joshi, I Ceballos-P, T Sardar, EJ Hess, YV Sun, Z Wen, ME Zwick, HA Jinnah Induced pluripotent stem cells from subjects with Lesch-Nyhan disease Scientific Reports, 2021;11(1):8523. 2021 [PMID: 33875724] (ICC, Human)
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• L Drakhlis, S Biswanath, CM Farr, V Lupanow, J Teske, K Ritzenhoff, A Franke, F Manstein, E Bolesani, H Kempf, S Liebscher, K Schenke-La, J Hegermann, L Nolte, H Meyer, J de la Roch, S Thiemann, C Wahl-Schot, U Martin, R Zweigerdt Human heart-forming organoids recapitulate early heart and foregut development Nature Biotechnology, 2021;0(0):. 2021 [PMID: 33558697] (IHC, Mouse)
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• Y Arioka, E Shishido, I Kushima, T Suzuki, R Saito, A Aiba, D Mori, N Ozaki Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons EBioMedicine, 2020;63(0):103138. 2020 [PMID: 33341442] (ICC, Human)
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• M Kinoshita, M Barber, W Mansfield, Y Cui, D Spindlow, GG Stirparo, S Dietmann, J Nichols, A Smith Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency Cell Stem Cell, 2020;0(0):. 2020 [PMID: 33271069] (Flow Cytometry, Mouse)
• R Fan, YS Kim, J Wu, R Chen, D Zeuschner, K Mildner, K Adachi, G Wu, S Galatidou, J Li, HR Schöler, SA Leidel, I Bedzhov Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause Nat Commun, 2020;11(1):5499. 2020 [PMID: 33127892] (ICC, Mouse)
• FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, C Villacorta, A Berical, JC Jean, J Le Suer, T Matte, C Simone-Roa, Y Tang, TM Schlaeger, AM Crane, N Matthias, SXL Huang, SH Randell, J Wu, JR Spence, G Carraro, BR Stripp, A Rab, EJ Sorsher, A Horani, SL Brody, BR Davis, DN Kotton Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells Cell Stem Cell, 2020;0(0):. 2020 [PMID: 33098807] (Flow Cytometry, Human)
• K Sekine, S Ogawa, S Tsuzuki, T Kobayashi, K Ikeda, N Nakanishi, K Takeuchi, E Kanai, Y Otake, S Okamoto, T Kobayashi, T Takebe, H Taniguchi Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media Sci Rep, 2020;10(1):17937. 2020 [PMID: 33087763] (ICC, Human)
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• LHW Kung, L Sampurno, KM Yammine, A Graham, P McDonald, JF Bateman, MD Shoulders, SR Lamandé CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A Stem Cell Res, 2020;48(0):101962. 2020 [PMID: 33002832] (Flow Cytometry, Human)
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• PA Barbuti, BFR Santos, CM Dording, G Cruciani, F Massart, A Hummel, R Krüger Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson�s disease patient carrying the heterozygous p.A30P mutation in SNCA Stem Cell Res, 2020;48(0):101951. 2020 [PMID: 32798915] (ICC, Human)
• L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 2020;0(0):. 2020 [PMID: 32783886] (IHC, Human)
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• LTP Khoa, YC Tsan, F Mao, DM Kremer, P Sajjakulnu, L Zhang, B Zhou, X Tong, NV Bhanu, C Choudhary, BA Garcia, L Yin, GD Smith, TL Saunders, SL Bielas, CA Lyssiotis, Y Dou Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation Cell Stem Cell, 2020;0(0):. 2020 [PMID: 32610040] (IHC, Mouse)
• PA Subramani, N Vartak-Sha, S Sreekumar, P Mathur, B Nayer, S Dakhore, SK Basavanna, DM Kalappa, RV Krishnamur, B Mukhi, P Mishra, N Yoshida, SK Ghosh, R Shandil, S Narayanan, B Campo, K Hasegawa, AR Anvikar, N Valecha, V Sundaramur Plasmodium vivax liver stage assay platforms using Indian clinical isolates Malar. J., 2020;19(1):214. 2020 [PMID: 32571333] (ICC, Human)
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• Y Nakatake, SBH Ko, AA Sharov, S Wakabayash, M Murakami, M Sakota, N Chikazawa, C Ookura, S Sato, N Ito, M Ishikawa-H, SS Mak, LM Jakt, T Ueno, K Hiratsuka, M Matsushita, SK Goparaju, T Akiyama, KI Ishiguro, M Oda, N Gouda, A Umezawa, H Akutsu, K Nishimura, R Matoba, O Ohara, MSH Ko Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors Cell Rep, 2020;31(7):107655. 2020 [PMID: 32433964] (ICC, Human)
• Y Ueda, C Kimura-Yos, K Mochida, M Tsume, Y Kameo, T Adachi, O Lefebvre, R Hiramatsu, I Matsuo Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis Cell Rep, 2020;31(7):107637. 2020 [PMID: 32433954] (IHC, Mouse)
• K Kamata, Y Otsuka, K Imamura, A Oishi, T Kondo, M Suga, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Yasukawa, H Usui, K Muguruma, A Tsujikawa, H Inoue Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration Stem Cell Res, 2020;45(0):101787. 2020 [PMID: 32416577] (ICC, Human)
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• M Tariq, H Liu, DP Ibañez, Y Li, S Chen, M Jiang, W Fan, P Zhao, Z Luo, D Wang, S Kanwal Generation of three induced pluripotent stem cell lines from a Parkinson's disease patient with mutant PARKIN�(p. C253Y) Stem Cell Res, 2020;45(0):101822. 2020 [PMID: 32387897] (Functional Assay, Human)
• A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation Mol Ther Methods Clin Dev, 2020;17(0):858-870. 2020 [PMID: 32373648] (ICC, Human)
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• J Frew, A Baradaran-, AD Balgi, X Wu, TD Yan, S Arns, FS Shidmoossa, J Tan, JB Jaquith, KR Jansen-Wes, FC Lynn, FB Gao, L Petrucelli, HH Feldman, IR Mackenzie, M Roberge, HB Nygaard Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency Mol Neurodegener, 2020;15(1):21. 2020 [PMID: 32178712] (ICC, Human)
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• S Yoshimatsu, T Sato, M Yamamoto, E Sasaki, M Nakajima, M Nakamura, S Shiozawa, T Noce, H Okano Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems Stem Cell Res, 2020;44(0):101740. 2020 [PMID: 32151954] (ICC, Callithrix jacchus (Marmoset))
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• A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids Nat. Cell Biol., 2020;22(1):60-73. 2020 [PMID: 31907413] (IF, Mouse)
• JR Alvarez-Do, J Donaghey, N Rasouli, JHR Kenty, A Helman, J Charlton, JR Straubhaar, A Meissner, DA Melton Circadian Entrainment Triggers Maturation of Human In�Vitro Islets Cell Stem Cell, 2019;26(1):108-122.e10. 2019 [PMID: 31839570] (ICC, Human)
• DM Barry, EA McMillan, B Kunar, R Lis, T Zhang, T Lu, E Daniel, M Yokoyama, JM Gomez-Sali, A Sureshbabu, O Cleaver, A Di Lorenzo, ME Choi, J Xiang, D Redmond, SY Rabbany, T Muthukumar, S Rafii Molecular determinants of nephron vascular specialization in the kidney Nat Commun, 2019;10(1):5705. 2019 [PMID: 31836710] (IHC, Mouse)
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• A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation Nat Commun, 2019;10(1):5462. 2019 [PMID: 31784515] (ICC, Mouse)
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• L Xie, J Huang, X Li, L Dai, X Lin, J Zhang, J Luo, W Zhang Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing Stem Cell Res, 2019;41(0):101610. 2019 [PMID: 31775087] (ICC, Human)
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• N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency Stem Cell Reports, 2019;13(6):1083-1098. 2019 [PMID: 31708477] (ICC, Human)
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Reviews for SOX17 Antibody (AF1924) (3)

Average Rating: 4.7

(Based on 3 reviews)

We have 3 reviews tested in 2 species: Human, Other.

reviewed by: Anonymous - IF Human 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 23658023
• Species: Human

reviewed by: Anonymous - IF Human 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 22613812
• Species: Human

reviewed by: Anonymous - IF Other 01/05/2015

Summary

• Application: Immunofluorescence
• Sample Tested: See PMIC 23418163
• Species: Other

Bioinformatics

• Gene Symbol: SOX17
• Uniprot:
  • Q9H6I2()