SOX7 Antibody [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Conjugate Size Price
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Catalog# & Formulation Size Price

SOX7 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human SOX7
Ser249-Ala345
Accession # Q9BT81
Specificity
Detects human SOX7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SOX1, -2, -3, -9, -10, and -17 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SOX7
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF2766 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX7 Antibody [Unconjugated]

  • MGC10895
  • SOX7 transcription factor
  • SOX7
  • SRY (sex determining region Y)-box 7
  • transcription factor SOX-7

Background

SOX7 belongs to the Sox (SRY-like HMG-box gene) family of transcription factors with diverse roles in development. SOX7 has been suggested to play a crucial role in parietal endoderm differentiation. SOX7 is expressed in many embryonic and adult tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOX7 Antibody (AF2766)(9)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 6 applications: Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Western Blot.


Filter By Application
Flow Cytometry
(1)
ICC
(3)
IHC
(1)
IHC-Fr
(1)
IHC-P
(1)
Western Blot
(2)
All Applications
Filter By Species
Human
(4)
Mouse
(5)
All Species
Showing Publications 1 - 9 of 9.
Publications using AF2766 Applications Species
N Hong, E Zhang, H Xie, L Jin, Q Zhang, Y Lu, AF Chen, Y Yu, B Zhou, S Chen, Y Yu, K Sun The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling Cell Death & Disease, 2021;12(4):393. 2021 [PMID: 33846290] (Flow Cytometry, Human) Flow Cytometry Human
J Klomp, J Hyun, J Klomp, K Pajcini, J Rehman, AB Malik Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells J. Biol. Chem., 2020;0(0):. 2020 [PMID: 32071080] (Western Blot, Human) Western Blot Human
IK Kim, K Kim, E Lee, DS Oh, CS Park, S Park, JM Yang, JH Kim, HS Kim, DT Shima, JH Kim, SH Hong, YH Cho, YH Kim, JB Park, GY Koh, YS Ju, HK Lee, S Lee, I Kim Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality J. Exp. Med., 2018;0(0):. 2018 [PMID: 29444818] (IHC-P, Mouse) IHC-P Mouse
AJ Lilly, A Mazan, DA Scott, G Lacaud, V Kouskoff SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development Mech. Dev., 2017;0(0):. 2017 [PMID: 28577909] (IHC, Mouse) IHC Mouse
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos Sci Rep, 2016;6(0):39457. 2016 [PMID: 27991575] (ICC, Mouse) ICC Mouse
Zhou Y, Williams J, Smallwood P, Nathans J Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina. PLoS ONE, 2015;10(12):e0143650. 2015 [PMID: 26630461] (IHC-Fr, Mouse) IHC-Fr Mouse
Behrens , Ann N, Zierold , Claudia, Shi , Xiaozhon, Ren , Yi, Koyano-Nakagawa , Naoko, Garry , Daniel J, Martin , Cindy M Sox7 is regulated by ETV2 during cardiovascular development. Stem Cells Dev, 2014;23(17):2004-13. 2014 [PMID: 24762086] (Western Blot, Human) Western Blot Human
Artus J, Panthier JJ, Hadjantonakis AK A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst. Development, 2010;137(20):3361-72. 2010 [PMID: 20826533] (ICC, Mouse) ICC Mouse
Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood, 2007;111(4):1933-41. 2007 [PMID: 18042803] (ICC, Human) ICC Human

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Product General Protocols

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Bioinformatics

Gene Symbol SOX7
Uniprot