Goat IgG Isotype Control [Unconjugated]

SH-SY5Y human neuroblastoma cell line was stained with Goat Anti-Human/Mouse/RatEphrin-B2 Antigen Affinity-purified Polyclonal Antibody (Catalog #AF496,filled histogram) or Normal Goat IgG Isotype Control Antibody(Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugatedAnti-Goat IgG Secondary Antibody (Catalog #F0107).

• Reactivity: Gt
• Applications: Ctrl
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Goat IgG Isotype Control [Unconjugated] Summary

• Immunogen: NA
• Specificity: Serum was obtained from naive (non-immunized) goats and purified for use as normal goat IgG.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IGHG1
• Purity Statement: Protein A or G purified
• Endotoxin Note: <0.10 EU per 1 μg of the antibody by the LAL method.

Applications/Dilutions

• Dilutions:
  • Control

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Dissolve the lyophilized goat IgG in sterile PBS, pH 7.4. If 1 mL of PBS is used, the antibody concentration will be 1 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Goat IgG Isotype Control [Unconjugated]

• IgG
• Immunoglobulin G
• ImmunoglobulinG

Background

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

Publications for IgG Isotype Control (AB-108-C)(354)

Publications using AB-108-C

• Y Zheng, X Dong, S Chen, Y He, J An, M Liu, L He, Y Zhang Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing BMC Oral Health, 2023;23(1):14. 2023-01-01 [PMID: 36627695] (Neutralization Control, Mouse)
• I Petit, A Levy, S Estrach, CC Féral, AG Trentin, F Dingli, D Loew, J Qu, H Zhou, C Théry, C Prunier, D Aberdam, O Ferrigno Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation Scientific Reports, 2022;12(1):22131. 2022-01-01 [PMID: 36550142] (Flow Cytometry, Human)
• G Xiao, R Kumar, Y Komuro, J Burguet, V Kakarla, I Azizkhania, SA Sheth, CK Williams, XR Zhang, M Macknicki, A Brumm, R Kawaguchi, P Mai, N Kaneko, HV Vinters, ST Carmichael, LA Havton, C DeCarli, JD Hinman IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury Cell Reports, 2022;41(12):111848. 2022-01-01 [PMID: 36543124] (Isotype Control, Mouse)
• Y Wang, S Zhang, Z Lan, V Doan, B Kim, S Liu, M Zhu, VL Hull, S Rihani, CL Zhang, JA Gray, F Guo SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice Cell Reports, 2022;41(12):111842. 2022-01-01 [PMID: 36543123] (ChIP, Mouse)
• J Van Coilli, T Pongracz, J Rahmöller, HJ Chen, CE Geyer, LA van Vught, JS Buhre, T Šušti?, TLJ van Osch, M Steenhuis, W Hoepel, W Wang, AS Lixenfeld, J Nouta, S Keijzer, F Linty, R Visser, MD Larsen, EL Martin, I Künsting, S Lehrian, V von Kopylo, C Kern, HB Lunding, M de Winther, N van Mourik, T Rispens, T Graf, MA Slim, RP Minnaar, MK Bomers, JJ Sikkens, APJ Vlaar, CE van der Sc, J den Dunnen, M Wuhrer, M Ehlers, G Vidarsson, Fatebenefr, UMC COVID- The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees EBioMedicine, 2022;87(0):104408. 2022-01-01 [PMID: 36529104] (Isotype Control, Human)
• WJ Brewer, AM Xet-Mull, A Yu, MI Sweeney, EM Walton, DM Tobin Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection Cell Reports, 2022;41(11):111817. 2022-01-01 [PMID: 36516756] (Isotype Control, Human)
• S Nugteren, Y Simons-Oos, CL Menckeberg, DH Hulleman-v, DJ Lindenberg, JN Samsom Endogenous secretory leukocyte protease inhibitor (SLPI) inhibits microbial-induced monocyte activation European Journal of Immunology, 2022;0(0):. 2022-01-01 [PMID: 36480463] (IHC, Human)
• D Spitzer, T Puetz, M Armbrust, M Dunst, J Macas, F Croll, KH Plate, Y Reiss, S Liebner, PN Harter, S Guérit, K Devraj Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke Scientific Reports, 2022;12(1):20925. 2022-01-01 [PMID: 36463381] (In Vivo, Mouse)
• SI Gringhuis, TM Kaptein, EBM Remmerswaa, A Drewniak, BA Wevers, B Theelen, GRAM D'Haens, T Boekhout, TBH Geijtenbee Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs Nature Immunology, 2022;0(0):. 2022-01-01 [PMID: 36456734] (Neutralization Control, Human)
• LE Langbein, E Sementino, Z Zhong, W Jiang, L Li, JR Testa, H Yang Data supporting the roles of BAP1, STING, and IFN-beta in ISGF3 activation in ccRCC Data in Brief, 2022;45(0):108743. 2022-01-01 [PMID: 36426057] (Neutralization Control, Human)
• V Jain, SL Harper, AM Versace, D Fingerman, GS Brown, M Bhardwaj, MAS Crissey, AR Goldman, G Ruthel, Q Liu, A Zivkovic, H Stark, M Herlyn, PA Gimotty, DW Speicher, RK Amaravadi Targeting UGCG overcomes resistance to lysosomal autophagy inhibition Cancer Discovery, 2022;0(0):. 2022-01-01 [PMID: 36331284] (Neutralization Control, Human)
• J Schulze Ho, J Schregel, QL Sciascia, Z Li, A Tuchschere, W Vahjen, CC Metges, J Zentek Effects of Oral Glutamine Supplementation, Birthweight and Age on Colonic Morphology and Microbiome Development in Male Suckling Piglets Microorganisms, 2022;10(10):. 2022-01-01 [PMID: 36296176] (IHC, Porcine)
• M Mizuno, A Fujioka, S Bitani, KI Minato, H Sakakibara Anti-Allergic Activity of Fucoidan Can Be Enhanced by Coexistence with Quercetin International Journal of Molecular Sciences, 2022;23(20):. 2022-01-01 [PMID: 36293027] (In Vivo Control, Mouse)
• EC Jeffery, TLA Mann, JA Pool, Z Zhao, SJ Morrison Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair Cell Stem Cell, 2022;29(11):1547-1561.e6. 2022-01-01 [PMID: 36272401] (Mouse)
• GL Lehmann, M Ginsberg, DJ Nolan, C Rodríguez, J Martínez-G, S Zeng, AP Voigt, RF Mullins, S Rafii, E Rodriguez-, I Benedicto Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells Cells, 2022;11(19):. 2022-01-01 [PMID: 36230937] (Isotype Control, Human)
• S Sonoda, S Murata, H Yamaza, R Yuniartha, J Fujiyoshi, K Yoshimaru, T Matsuura, Y Oda, S Ohga, T Tajiri, T Taguchi, T Yamaza Targeting hepatic oxidative stress rescues bone loss in liver fibrosis Molecular Metabolism, 2022;66(0):101599. 2022-01-01 [PMID: 36113772] (Neutralization Control, Mouse)
• AM Mello, T Ngodup, Y Lee, KL Donahue, J Li, A Rao, ES Carpenter, HC Crawford, M Pasca di M, KE Lee Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer Oncogenesis, 2022;11(1):56. 2022-01-01 [PMID: 36109493] (Neutralization Control, Mouse)
• Y Xu, M Twarog, N Li, A Banks, J Schustak, Y Bao, Q Huang, QG Medley Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells PLoS ONE, 2022;17(7):e0271656. 2022-01-01 [PMID: 35901031] (Isotype Control, Human)
• J Huang, Y Mao, Q Li, H Hong, N Tang, X Kang, Y Huang, J Liu, Q Gong, Y Yao, L Li Kallistatin prevents ovarian hyperstimulation syndrome by regulating vascular leakage Journal of Cellular and Molecular Medicine, 2022;26(16):4613-4623. 2022-01-01 [PMID: 35866203] (Isotype Control, Mouse)
• QY Li, SX Chen, JY Liu, PW Yao, YW Duan, YY Li, Y Zang Neuroinflammation in the anterior cingulate cortex: the potential supraspinal mechanism underlying the mirror-image pain following motor fiber injury Journal of Neuroinflammation, 2022;19(1):162. 2022-01-01 [PMID: 35725625] (Isotype Control, Rat)
• S Rauskolb, T Andreska, S Fries, CR von Collen, R Blum, CM Monoranu, C Villmann, M Sendtner Insulin-like growth factor 5 associates with human A� plaques and promotes cognitive impairment Acta neuropathologica communications, 2022;10(1):68. 2022-01-01 [PMID: 35513854] (IHC Control, Human)
• J Schregel, J Schulze Ho, QL Sciascia, Z Li, S Görs, A Eggert, A Tuchschere, J Zentek, CC Metges Effects of oral glutamine supplementation on jejunal morphology, development, and amino acid profiles in male low birth weight suckling piglets PLoS ONE, 2022;17(4):e0267357. 2022-01-01 [PMID: 35476806] (IHC, Porcine)
• C Junqueira, Â Crespo, S Ranjbar, LB de Lacerda, M Lewandrows, J Ingber, B Parry, S Ravid, S Clark, MR Schrimpf, F Ho, C Beakes, J Margolin, N Russell, K Kays, J Boucau, U Das Adhika, SM Vora, V Leger, L Gehrke, L Henderson, E Janssen, D Kwon, C Sander, J Abraham, MB Goldberg, H Wu, G Mehta, S Bell, AE Goldfeld, MR Filbin, J Lieberman FcgammaR-mediated SARS-CoV-2 infection of monocytes activates inflammation Nature, 2022;0(0):. 2022-01-01 [PMID: 35385861] (Flow Cytometry, Human)
• A Skopál, T Kéki, PÁ Tóth, B Csóka, B Koscsó, ZH Német, L Antonioli, A Ivessa, F Ciruela, L Virág, G Haskó, E Kókai Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling The Journal of Biological Chemistry, 2022;0(0):101888. 2022-01-01 [PMID: 35367412] (Immunoprecipitation Control, Mouse)
• Y Menuchin-L, A Schreiber, A Lecanda, A Mecate-Zam, L Brunotte, OE Psathaki, S Ludwig, T Rauen, HR Schöler SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids Stem Cell Reports, 2022;0(0):. 2022-01-01 [PMID: 35334213] (Neutralization, Human)
• K Molnár, B Nógrádi, R Kristóf, Á Mészáros, K Pajer, L Siklós, A Nógrádi, I Wilhelm, IA Krizbai Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury Journal of Neuroinflammation, 2022;19(1):68. 2022-01-01 [PMID: 35305649] (Western Blot, Mouse)
• SK Singh, K Krukowski, GO Laumet, D Weis, JF Alexander, CJ Heijnen, A Kavelaars CD8+ T cell-derived IL-13 increases macrophage IL-10 to resolve neuropathic pain JCI Insight, 2022;7(5):. 2022-01-01 [PMID: 35260535] (In Vivo, Mouse)
• K Kos, MA Aslam, R van de Ven, MD Wellenstei, W Pieters, A van Weverw, DEM Duits, K van Pul, CS Hau, K Vrijland, D Kaldenbach, EAM Raeven, SA Quezada, R Beyaert, H Jacobs, TD de Gruijl, KE de Visser Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche Cell Reports, 2022;38(9):110447. 2022-01-01 [PMID: 35235800] (Neutralization Control, Mouse)
• EM Quezada-Ma, YI Chirino, ME Gonsebatt, R Morales-Bá, Y Sánchez-Pé, CM García-Cue Nucleotide Excision Repair Pathway Activity Is Inhibited by Airborne Particulate Matter (PM10) through XPA Deregulation in Lung Epithelial Cells International Journal of Molecular Sciences, 2022;23(4):. 2022-01-01 [PMID: 35216341] (Immunoprecipitation, Human)
• X Liu, W Chen, G Zhu, H Yang, W Li, M Luo, C Shu, Z Zhou Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection Cell Discovery, 2022;8(1):11. 2022-01-01 [PMID: 35132073] (IHC Control, Mouse)
• LJ Fan, HM Kan, XT Chen, YY Sun, LP Chen, W Shen Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain Molecular pain, 2022;18(0):1744806922107. 2022-01-01 [PMID: 35083936] (In Vivo Control, Mouse)
• A Ichikawa, S Neo, R Nukui, Y Yamada, S Nitta, H Iwaki, Y Yanagi, K Nakayama, S Sato, S Tateishi, M Hisasue Establishment of large canine hepatocyte spheroids by mixing vascular endothelial cells and canine adipose-derived mesenchymal stem cells Regenerative Therapy, 2022;19(0):1-8. 2022-01-01 [PMID: 35024388] (IHC Control, Canine)
• IC Kreft, RRA Winiarczyk, FJ Tanis, C van der Zw, KS Schmitz, AJ Hoogendijk, RL de Swart, A Moscona, M Porotto, DCF Salvatori, RD de Vries, MPM de Maat, M van den Bi, BJM van Vlijme, Dutch Covi Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model Thrombosis Research, 2021;210(0):6-11. 2021-01-01 [PMID: 34954402] (IHC Control, Ferret)
• J Wang, G Yang, X Wang, Z Wen, L Shuai, J Luo, C Wang, Z Sun, R Liu, J Ge, X He, R Hua, X Wang, X Yang, W Chen, G Zhong, Z Bu SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells Cell Discovery, 2021;7(1):119. 2021-01-01 [PMID: 34903715] (Neutralization, Human)
• P Li, Q Li, N Biswas, H Xin, T Diemer, L Liu, L Perez Guti, G Paternostr, C Piermarocc, S Domanskyi, RK Wang, N Ferrara LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy Embo Molecular Medicine, 2021;0(0):e14511. 2021-01-01 [PMID: 34779136] (Neutralization Control, Bovine)
• D Olmeda, D Cerezo-Wal, C Mucientes, TG Calvo, E Cañón, D Alonso-Cur, N Ibarz, J Muñoz, JL Rodriguez-, P Ortiz-Rome, S Ortega, MS Soengas Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics Embo Molecular Medicine, 2021;0(0):e12924. 2021-01-01 [PMID: 34762341] (Neutralization Control, Human)
• E Gomez-Esco, J Burlaud-Ga, C Visdeloup, ARE Silva, P Coutant, P Roingeard, E Beaumont Incorporation of apolipoprotein E into HBV-HCV subviral envelope particles to improve the hepatitis vaccine strategy Scientific Reports, 2021;11(1):21856. 2021-01-01 [PMID: 34750487] (Co-Immunoprecipitation, Hamster)
• N Sheshadri, DK Poria, S Sharan, Y Hu, C Yan, VN Koparde, K Balamuruga, E Sterneck PERK signaling through C/EBPdelta contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells Cell Death & Disease, 2021;12(11):1038. 2021-01-01 [PMID: 34725321] (Functional Assay, Human)
• JE Miller, H Lingegowda, LK Symons, O Bougie, SL Young, BA Lessey, M Koti, C Tayade Interleukin-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis JCI Insight, 2021;0(0):. 2021-01-01 [PMID: 34699382] (In Vivo, Mouse)
• KM Lugo-Cintr, JM Ayuso, M Humayun, MM Gong, SC Kerr, SM Ponik, PM Harari, M Virumbrale, DJ Beebe Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model EBioMedicine, 2021;73(0):103634. 2021-01-01 [PMID: 34673450] (Neutralization Control, Human)
• YC Chen, CY Chien, CC Hsu, CH Lee, YT Chou, SG Shiah, SY Liu, CY Yen, AC Hsieh, M Wabitsch, YS Shieh Obesity-associated leptin promotes chemoresistance in colorectal cancer through YAP-dependent AXL upregulation American journal of cancer research, 2021;11(9):4220-4240. 2021-01-01 [PMID: 34659884] (In Vivo, Mouse)
• J Obst, HL Hall-Rober, TB Smith, M Kreuzer, L Magno, E Di Daniel, JB Davis, E Mead PLCgamma2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages Scientific Reports, 2021;11(1):19842. 2021-01-01 [PMID: 34615897] (Control, Human)
• Y Wang, Y Zhang, S Zhang, B Kim, VL Hull, J Xu, P Prabhu, M Gregory, V Martinez-C, X Zhan, W Deng, F Guo PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination Cell Reports, 2021;37(1):109695. 2021-01-01 [PMID: 34610310] (Immunoprecipitation, Mouse)
• E Jackson, N Lara-Casti, MP Akhter, M Dallas, JM Scott, T Ganesh, ML Johnson Osteocyte Wnt/beta-catenin pathway activation upon mechanical loading is altered in ovariectomized mice Bone Reports, 2021;15(0):101129. 2021-01-01 [PMID: 34584905] (IHC Control, Mouse)
• M Shimizu, YI Koma, H Sakamoto, S Tsukamoto, Y Kitamura, S Urakami, K Tanigawa, T Kodama, N Higashino, M Nishio, M Shigeoka, Y Kakeji, H Yokozaki Metallothionein 2A Expression in Cancer-Associated Fibroblasts and Cancer Cells Promotes Esophageal Squamous Cell Carcinoma Progression Cancers, 2021;13(18):. 2021-01-01 [PMID: 34572779] (Neutralization Control, Human)
• K Wu, J Feng, F Lyu, F Xing, S Sharma, Y Liu, SY Wu, D Zhao, A Tyagi, RP Deshpande, X Pei, MG Ruiz, H Takahashi, S Tsuzuki, T Kimura, YY Mo, Y Shiozawa, R Singh, K Watabe Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Nature Communications, 2021;12(1):5196. 2021-01-01 [PMID: 34465793] (Binding Assay, Human)
• P Szodoray, TK Andersen, J Heinzelbec, JF Imbery, PC Huszthy, SM Stanford, B Bogen, OB Landsverk, N Bottini, A Tveita, LA Munthe, B Nakken Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity Cell Reports, 2021;36(6):109525. 2021-01-01 [PMID: 34380042] (Isotype Control, Human)
• Y Yamaguchi, M Ohshima Local administration of anti-hepatocyte growth factor-neutralizing antibody reverts naturally occurring periodontitis Journal of oral biosciences, 2021;0(0):. 2021-01-01 [PMID: 34303825] (Functional Assay Control, Human)
• EU Okoro TNFalpha-Induced LDL Cholesterol Accumulation Involve Elevated LDLR Cell Surface Levels and SR-B1 Downregulation in Human Arterial Endothelial Cells International Journal of Molecular Sciences, 2021;22(12):. 2021-01-01 [PMID: 34207810] (Isotype Control, Human)
• C Xie, F Ye, N Zhang, Y Huang, Y Pan, X Xie CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype Journal of Cellular and Molecular Medicine, 2021;0(0):. 2021-01-01 [PMID: 34189838] (Neutralization Control, Mouse)
• P Lian, S Braber, S Varasteh, HJ Wichers, G Folkerts Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture Scientific Reports, 2021;11(1):13186. 2021-01-01 [PMID: 34162953] (ICC, Human)
• GHP Ngo, JW Grimstead, DM Baird UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair Nature Communications, 2021;12(1):3849. 2021-01-01 [PMID: 34158508] (ChIP Control, Human)
• SH Hong, G Han, SJ Lee, J Cocquet, C Cho Testicular germ cell-specific lncRNA, Teshl, is required for complete expression of Y chromosome genes and a normal offspring sex ratio Science Advances, 2021;7(24):. 2021-01-01 [PMID: 34108217] (ChIP, Mouse)
• V Grotheer, N Skrynecki, L Oezel, J Grassmann, J Windolf, CV Suschek Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence Scientific Reports, 2021;11(1):11968. 2021-01-01 [PMID: 34099837] (Flow Cytometry, Human)
• S Ghosh, NB Nataraj, A Noronha, S Patkar, A Sekar, S Mukherjee, S Winograd-K, L Kramarski, A Verma, M Lindzen, DD Garcia, J Green, G Eisenberg, H Gil-Henn, A Basu, Y Lender, S Weiss, M Oren, M Lotem, B Geiger, E Ruppin, Y Yarden PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR Cell Reports, 2021;35(8):109181. 2021-01-01 [PMID: 34038737] (Immunoprecipitation, Human)
• F Wanke, S Gutbier, A Rümmelin, M Steinberg, LD Hughes, M Koenen, J Komuczki, D Regan-Komi, S Wagage, J Hesselmann, R Thoma, D Brugger, T Christopei, H Wang, F Point, R Hallet, S Ghosh, CV Rothlin, C Patsch, B Geering Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages Cell Death & Disease, 2021;12(6):538. 2021-01-01 [PMID: 34035216] (Isotype Control, Human)
• A Chu, SY Kok, J Tsui, MC Lin, B Aguirre, M Wadehra Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface Journal of reproductive immunology, 2021;145(0):103309. 2021-01-01 [PMID: 33774530] (IHC, Mouse)
• M Wendimu, M Alqinyah, S Vella, P Dean, F Almutairi, RD Rivera, S Rayatpishe, J Wohlschleg, S Moreno, SB Hooks RGS10 physically and functionally interacts with STIM2 and requires store-operated calcium entry to regulate proinflammatory gene expression in microglia Cellular Signalling, 2021;0(0):109974. 2021-01-01 [PMID: 33705894] (Immunoprecipitation, Mouse)
• FY Mao, YP Lv, CJ Hao, YS Teng, YG Liu, P Cheng, SM Yang, W Chen, T Liu, QM Zou, R Xie, JY Xu, Y Zhuang Helicobacter pylori-induced Rev-erb&amp;alpha fosters gastric bacteria colonization by impairing host innate and adaptive defense Cellular and Molecular Gastroenterology and Hepatology, 2021;0(0):. 2021-01-01 [PMID: 33676046] (Neutralization, Human)
• JJ McGuire, JS Frieling, CH Lo, T Li, A Muhammad, HR Lawrence, NJ Lawrence, LM Cook, CC Lynch Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer Nature Communications, 2021;12(1):723. 2021-01-01 [PMID: 33526787] (Isotype Control, Human)
• S Ren, L Breuillaud, W Yao, T Yin, KA Norris, SP Zehntner, L D'Adamio TNF-&amp;alpha-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer&#039;s disease pathology in young Trem2R47H rats The Journal of Biological Chemistry, 2020;296(0):100089. 2020-01-01 [PMID: 33434745] (Neutralization Control, Rat)
• RV Broad, SJ Jones, MC Teske, LM Wastall, AM Hanby, JL Thorne, TA Hughes Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy British Journal of Cancer, 2021;0(0):. 2021-01-01 [PMID: 33398063] (Isotype Control, Human)
• Z Wang, Y Wang, N Bradbury, C Gonzales B, B Schnabl, A Di Nardo Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes Scientific Reports, 2020;10(1):21732. 2020-01-01 [PMID: 33303806] (Cell Culture, Human)
• Y Ishida, Y Kuninaka, M Nosaka, A Kimura, A Taruya, M Furuta, N Mukaida, T Kondo Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3-CCR5 axis Nat Commun, 2020;11(1):5994. 2020-01-01 [PMID: 33239616] (In Vivo, Mouse)
• K Kongmanas, N Punyadee, K Wasuworawo, A Songjaeng, T Prommool, Y Pewkliang, S Manocheewa, S Thiemmeca, K Sa-Ngiamsu, C Puttikhunt, KF Faull, S Hongeng, P Avirutnan Immortalized stem cell-derived hepatocyte-like cells: An alternative model for studying dengue pathogenesis and therapy PLoS Negl Trop Dis, 2020;14(11):e0008835. 2020-01-01 [PMID: 33216752] (Flow Cytometry, Human)
• S Ren, L Breuillaud, W Yao, T Yin, KA Norris, SP Zehntner, L D'Adamio TNF-&amp;alpha-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer&#039;s disease pathology in young Trem2R47H �rats J Biol Chem, 2020;0(0):. 2020-01-01 [PMID: 33199501] (IHC, Rat)
• R Kajino-Sak, T Fujishita, MM Taketo, M Aoki Synthetic lethality between MyD88 loss and mutations in Wnt/&amp;beta-catenin pathway in intestinal tumor epithelial cells Oncogene, 2020;0(0):. 2020-01-01 [PMID: 33177648] (In Vivo, Mouse)
• JC DuBois, AK Ray, P Davies, B Shafit-Zag Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis J Neuroinflammation, 2020;17(1):324. 2020-01-01 [PMID: 33121494] (Functional Assay, Mouse)
• E Kawashita, K Ishihara, H Miyaji, Y Tanishima, A Kiriyama, O Matsuo, S Akiba &amp;alpha2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline Mol Brain, 2020;13(1):140. 2020-01-01 [PMID: 33059734] (Control, Mouse)
• PL Mulcrone, SKE Edwards, DN Petrusca, LS Haneline, J Delgado-Ca, GD Roodman Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23 Sci Rep, 2020;10(1):17319. 2020-01-01 [PMID: 33057033] (Control, Human)
• YY Liang, XB Deng, XT Lin, LL Jiang, XT Huang, ZW Mo, YW Yuan, MT Teh RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner Cell Death Dis, 2020;11(10):855. 2020-01-01 [PMID: 33057010] (Control, Human)
• CH Pai, SR Lin, CH Liu, SY Pan, H Hsu, YT Chen, CT Yen, IS Yu, HL Wu, SL Lin, SW Lin Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis Sci Rep, 2020;10(1):16772. 2020-01-01 [PMID: 33033277] (Isotype Control, Mouse)
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Reviews for IgG Isotype Control (AB-108-C) (2)

Average Rating: 5

(Based on 2 reviews)

reviewed by: Rita Matta 05/07/2019

Summary

• Lot: es4118071

reviewed by: Juwen DuBois 04/07/2017

Summary

• Lot: ES4116081

Comments

• Comments: Used ad an in vivo control. [In vivo] EAE was induced in C57BL/6 mice by immunization with an emulsion of MOG35-55 in complete Freund's adjuvant (CFA), followed by administration of pertussis toxin (PTX) in PBS, first on the day of immunization and then again 2 days later. Mice were then injected with a total of 40ug Normal Goat IgG (R&D AB108C) vs. PBS (100ul 1x PBS). A 100ul volume of 10ug Normal Goat IgG was injected intravenously every other day starting at day 13 post MOG for a total of 4 injections. Clinical scores were measured daily using the following scoring scale: 0) Normal mouse; no overt signs of disease; 1) Limp tail or hind limb weakness; 2)Limp tail and hind limb weakness; 3) Partial hind limb paralysis; 4)Complete hind limb paralysis; 5) Moribund state; death by EAE.

Bioinformatics

• Gene Symbol: IGHG1