HNF-3 beta/FoxA2 Antibody [Unconjugated]

Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, Jurkat human acute T cell leukemia cell line, and K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for HNF‑3 beta /FoxA2 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Mouse splenocytes were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. HNF‑3 beta /FoxA2/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 μL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. The E-RABP promoter was detected by standard PCR.

HNF‑3 beta /FoxA2 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

HNF‑3 beta /FoxA2 was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human HNF‑3 beta /FoxA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2400) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

• Reactivity: Hu
• Applications: WB, IHC, ChIP, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

HNF-3 beta/FoxA2 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human HNF‑3 beta /FoxA2
  Met242-Ser457
  Accession # Q9Y261
• Specificity: Detects human HNF‑3 beta /FoxA2 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FOXA2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells
  • Immunocytochemistry 5-15 ug/mL
  • Immunohistochemistry 3-15 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HNF-3 beta/FoxA2 Antibody [Unconjugated]

• forkhead box A2
• Forkhead box protein A2
• FoxA2
• hepatic nuclear factor-3-beta
• hepatocyte nuclear factor 3, beta
• hepatocyte nuclear factor 3-beta
• HNF3 beta
• HNF-3 beta
• HNF-3B
• HNF-3-beta
• HNF3BTCF-3B
• MGC19807
• TCF3B
• Transcription factor 3B

Background

HNF-3 beta , also known as FoxA2, is a member of the forkhead class of DNA-binding proteins. It is a transcriptional activator for liver-specific transcripts such as albumin and transthyretin. Similar family members play roles in the differentiation of the pancreas and liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HNF-3 beta/FoxA2 Antibody (AF2400)(56)

Publications using AF2400

• T Tada, H Ohnishi, N Yamamoto, F Kuwata, Y Hayashi, H Okuyama, T Morino, Y Kasai, H Kojima, K Omori Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats Regenerative Therapy, 2022;19(0):77-87. 2022 [PMID: 35097166] (IHC, Rat)
• P Aldrin-Kir, M Åkerblom, T Cardoso, S Nolbrant, AF Adler, X Liu, A Heuer, M Davidsson, M Parmar, T Björklund A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants Stem Cell Reports, 2021;17(1):159-172. 2021 [PMID: 34971563] (ICC, Human)
• RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandrat, DA Roberts, J Wang, S Kefalopoul, A Ramirez, Y Qiu, J Chiou, KJ Gaulton, B Ren, DN Kotton, M Sander Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Nature Communications, 2021;12(1):6636. 2021 [PMID: 34789735] (ChIP, Human)
• T Bluhmki, S Traub, AK Müller, S Bitzer, E Schruf, MT Bammert, M Leist, F Gantner, JP Garnett, R Heilker Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model Scientific Reports, 2021;11(1):17028. 2021 [PMID: 34426605] (IHC, Human)
• A Fütterer, A Talavera-G, T Pons, J de Celis, J Gutiérrez, V Domínguez, C Martínez-A Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels Cell Death & Disease, 2021;12(7):637. 2021 [PMID: 34155199] (IHC, Human)
• S Chen, Y Han, L Yang, T Kim, M Nair, O Harschnitz, P Wang, J Zhu, SY Koo, X Tang, L Lacko, V Chandar, Y Bram, T Zhang, W Zhang, F He, J Caicedo, Y Huang, T Evans, P van der Va, MJ Titulaer, JKH Spoor, RL Furler, P Canoll, J Goldman, S Przedborsk, R Schwartz, D Ho, L Studer SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence Research square, 2021;0(0):. 2021 [PMID: 34031650] (IHC, Human)
• H Mou, Y Yang, MA Riehs, J Barrios, M Shivaraju, AL Haber, DT Montoro, K Gilmore, EA Haas, B Paunovic, J Rajagopal, SO Vargas, RL Haynes, A Fine, WV Cardoso, X Ai Airway basal stem cells generate distinct subpopulations of PNECs Cell Reports, 2021;35(3):109011. 2021 [PMID: 33882306] (ICC, Human)
• G Guo, GG Stirparo, SE Strawbridg, D Spindlow, J Yang, J Clarke, A Dattani, A Yanagida, MA Li, S Myers, BN Özel, J Nichols, A Smith Human naive epiblast cells possess unrestricted lineage potential Cell Stem Cell, 2021;0(0):. 2021 [PMID: 33831366] (ICC, Human)
• Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, Y Chen, S Phillips, JE Holden, V Bondarenko, WF Block, TE Barnhart, N Schultz-Da, K Brunner, H Simmons, BT Christian, ME Emborg, SC Zhang Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys Nature Medicine, 2021;0(0):. 2021 [PMID: 33649496] (ICC, Primate - Rhesus macaque)
• TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use Cell Stem Cell, 2021;28(2):343-355.e5. 2021 [PMID: 33545081] (ICC, Human)
• J Piao, S Zabierowsk, BN Dubose, EJ Hill, M Navare, N Claros, S Rosen, K Ramnarine, C Horn, C Fredrickso, K Wong, B Safford, S Kriks, A El Maarouf, U Rutishause, C Henchcliff, Y Wang, I Riviere, S Mann, V Bermudez, S Irion, L Studer, M Tomishima, V Tabar Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01 Cell Stem Cell, 2021;28(2):217-229.e7. 2021 [PMID: 33545080] (Flow Cytometry, Human)
• B Kuebler, B Aran, R Flores, LA Pérez-Jura, A Veiga, R Corominas, I Cuscó Generation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering Williams-Beuren syndrome (7q11.23 deletion) Stem Cell Research, 2020;49(0):102087. 2020 [PMID: 33370870] (Flow Cytometry, Human)
• B Kuebler, B Aran, R Flores, LA Pérez-Jura, A Veiga, I Cuscó, R Corominas Derivation of induced pluripotent stem cells (iPSCs) by retroviral transduction of skin fibroblasts from four patients suffering 7q11.23 microduplication syndrome Stem Cell Res, 2020;49(0):102092. 2020 [PMID: 33254092] (ICC, Human)
• M Inglés-Fer, M Martin-Ina, L Herrera, M Villaverde, S Santos, MA Vesga, E Garreta, I Martín-Rui, AM Aransay, J Anguita, B Barreña, LM Allende, LI Gonzalez-G, C Eguizabal Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with activated PI3 kinase delta syndrome (APDS2) Stem Cell Res, 2020;49(0):102082. 2020 [PMID: 33221676] (ICC, Human)
• E Naumovska, G Aalderink, C Wong Valen, K Kosim, A Nicolas, S Brown, P Vulto, KS Erdmann, D Kurek Direct On-Chip Differentiation of Intestinal Tubules from Induced Pluripotent Stem Cells Int J Mol Sci, 2020;21(14):. 2020 [PMID: 32674311] (ICC, Human)
• Z Yang, X Jiang, Z Zhang, Z Zhao, W Xing, Y Liu, X Jiang, H Zhao HDAC3-dependent transcriptional repression of FOXA2 regulates FTO/m6A/MYC signaling to contribute to the development of gastric cancer Cancer Gene Ther., 2020;0(0):. 2020 [PMID: 32655129] (Immunoprecipitation, Mouse)
• S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi Generation of intestinal organoids derived from human pluripotent stem cells for drug testing Sci Rep, 2020;10(1):5989. 2020 [PMID: 32249832] (ICC, Human)
• NV Fuchs, M Schieck, M Neuenkirch, C Tondera, H Schmitz, L Wendeburg, D Steinemann, C Elpers, F Rutsch, R König Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Gouti�res syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1) Stem Cell Res, 2020;43(0):101697. 2020 [PMID: 32062129] (ICC, Human)
• YY Kim, H Kim, CS Suh, HC Liu, Z Rosenwaks, SY Ku Effects of Natural Progesterone and Synthetic Progestin on Germ Layer Gene Expression in a Human Embryoid Body Model Int J Mol Sci, 2020;21(3):. 2020 [PMID: 31991577] (ICC, Human)
• N Bredenkamp, J Yang, J Clarke, GG Stirparo, F von Meyenn, S Dietmann, D Baker, R Drummond, Y Ren, D Li, C Wu, M Rostovskay, S Eminli-Mei, A Smith, G Guo Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency Stem Cell Reports, 2019;13(6):1083-1098. 2019 [PMID: 31708477] (ICC, Human)
• M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, K Dam, D Acehan, LS Ramos-Espi, W Wang, J Zhang, JW Shim, G Ciceri, L Brichta, L Studer, P Greengard Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons Cell Stem Cell, 2019;25(4):514-530.e8. 2019 [PMID: 31543366] (ICC, Human)
• K Lee, H Cho, RW Rickert, QV Li, J Pulecio, CS Leslie, D Huangfu FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation Cell Rep, 2019;28(2):382-393.e7. 2019 [PMID: 31291575] (Western Blot, Human)
• R Yokoi, M Okabe, N Matsuda, A Odawara, A Karashima, I Suzuki Impact of Sleep-Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons Front Neurosci, 2019;13(0):554. 2019 [PMID: 31191238] (ICC, Human)
• C Calatayud, G Carola, I Fernández-, M Valtorta, S Jiménez-De, M Díaz, J Soriano-Fr, G Cappellett, J García-San, Á Raya, A Consiglio CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons Sci Rep, 2019;9(1):6811. 2019 [PMID: 31048719] (ICC, Human)
• T Zhou, TW Kim, CN Chong, L Tan, S Amin, Z Sadat Badi, S Mukherjee, Z Ghazizadeh, H Zeng, M Guo, M Crespo, T Zhang, R Kenyon, CL Robinson, E Apostolou, H Wang, JZ Xiang, T Evans, L Studer, S Chen A hPSC-based platform to discover gene-environment interactions that impact human ?-cell and dopamine neuron survival Nat Commun, 2018;9(1):4815. 2018 [PMID: 30446643] (ICC, Human)
• H Ida, T Akiyama, K Ishiguro, SK Goparaju, Y Nakatake, N Chikazawa-, S Sato, H Kimura, Y Yokoyama, M Nagino, MSH Ko, SBH Ko Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors Stem Cell Res Ther, 2018;9(1):277. 2018 [PMID: 30359326] (ICC, Human)
• E Senís, L Mosteiro, S Wilkening, E Wiedtke, A Nowrouzi, S Afzal, R Fronza, H Landerer, M Abad, D Niopek, M Schmidt, M Serrano, D Grimm AAVvector-mediated in vivo reprogramming into pluripotency Nat Commun, 2018;9(1):2651. 2018 [PMID: 29985406] (ICC, Mouse)
• B Kuebler, B Aran, L Miquel-Ser, Y Muñoz, E Ars, G Bullich, M Furlano, R Torra, M Marti, A Veiga, A Raya Generation of integration-free induced pluripotent stem cell lines derived from two patients with X-linked Alport syndrome (XLAS) Stem Cell Res, 2017;0(0):. 2017 [PMID: 29150092] (ICC, Human)
• L Miquel-Ser, A Duarri, Y Muñoz, B Kuebler, B Aran, C Costa, M Martí, M Comabella, S Malhotra, X Montalban, A Veiga, A Raya Generation of six multiple sclerosis patient-derived induced pluripotent stem cell lines Stem Cell Res, 2017;24(0):155-159. 2017 [PMID: 29034884] (ICC, Human)
• KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells Stem Cell Reports, 2017;0(0):. 2017 [PMID: 28602613] (ICC, Human)
• Y Kondo, T Toyoda, R Ito, M Funato, Y Hosokawa, S Matsui, T Sudo, M Nakamura, C Okada, X Zhuang, A Watanabe, A Ohta, N Inagaki, K Osafune Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells Diabetologia, 2017;0(0):. 2017 [PMID: 28534195] (ICC, Human)
• JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency Cell Rep, 2017;19(1):20-35. 2017 [PMID: 28380358] (Flow Cytometry, Human)
• F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells Nat Protoc, 2017;12(4):814-827. 2017 [PMID: 28333915] (Flow Cytometry, Human)
• A Shiraishi, K Muguruma, Y Sasai Generation of thalamic neurons from mouse embryonic stem cells Development, 2017;0(0):. 2017 [PMID: 28219951] (ICC, Mouse)
• Leslie E Rogler Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver J. Histochem. Cytochem., 2016;0(0):. 2016 [PMID: 27879410] (ICC, Human)
• Cell Expansion During Directed Differentiation Of Stem Cells Toward The Hepatic Lineage Stem Cells Dev., 2016;0(0):. 2016 [PMID: 27806669] (CyTof, Human)
• Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells Sci Rep, 2016;6(0):31063. 2016 [PMID: 27507707] (IHC, Mouse)
• Tsankov A, Akopian V, Pop R, Chetty S, Gifford C, Daheron L, Tsankova N, Meissner A A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells. Nat Biotechnol, 2015;33(11):1182-92. 2015 [PMID: 26501952] (IHC-P, Human)
• Villa-Diaz L, Kim J, Lahann J, Krebsbach P Derivation and long-term culture of transgene-free human induced pluripotent stem cells on synthetic substrates. Stem Cells Transl Med, 2014;3(12):1410-7. 2014 [PMID: 25313201] (ICC, Human)
• Hartfield , Elizabet, Yamasaki-Mann , Michiko, Ribeiro Fernandes , Hugo J, Vowles , Jane, James , William, Cowley , Sally A, Wade-Martins , Richard Physiological characterisation of human iPS-derived dopaminergic neurons. PLoS ONE, 2014;9(2):e87388. 2014 [PMID: 24586273] (IHC-Fr, Human)
• Szablowska-Gadomska , Ilona, Sypecka , Joanna, Zayat , Valery, Podobinska , Martyna, Pastwinska , Anna, Pienkowska-Grela , Barbara, Buzanska , Leonora Treatment with small molecules is an important milestone towards the induction of pluripotency in neural stem cells derived from human cord blood. Acta Neurobiol Exp (Wars), 2012;72(4):337-50. 2012 [PMID: 23377265] (ICC, Human)
• Montserrat N, Ramirez-Bajo MJ, Xia Y, Sancho-Martinez I, Moya-Rull D, Miquel-Serra L, Yang S, Nivet E, Cortina C, Gonzalez F, Izpisua Belmonte JC, Campistol JM Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, oct4 and sox2. J. Biol. Chem., 2012;287(29):24131-8. 2012 [PMID: 22613719] (ICC, Human)
• Prabakar K, Dominguez-Bendala J, Molano R, Pileggi A, Villate S, Ricordi C, Inverardi L Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells. Cell Transplant, 2012;21(6):1321-39. 2012 [PMID: 22195604] (ICC, Human)
• Eguizabal C, Montserrat N, Vassena R, Barragan M, Garreta E, Garcia-Quevedo L, Vidal F, Giorgetti A, Veiga A, Belmonte JC Complete meiosis from human induced pluripotent stem cells. Stem Cells, 2011;29(8):1186-95. 2011 [PMID: 21681858] (ICC, Human)
• Bone HK, Nelson AS, Goldring CE, Tosh D, Welham MJ A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J. Cell. Sci., 2011;124(0):1992-2000. 2011 [PMID: 21610099] (ICC, Human)
• Jiang W, Sui X, Zhang D, Liu M, Ding M, Shi Y, Deng H CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Stem Cells, 2011;29(4):609-17. 2011 [PMID: 21308865] (ICC, Human)
• Klim JR, Li L, Wrighton PJ A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat. Methods, 2010;7(12):989-94. 2010 [PMID: 21076418] (ICC, Human)
• Chayosumrit M, Tuch B, Sidhu K Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. Biomaterials, 2010;31(3):505-14. 2010 [PMID: 19833385] (Western Blot, Human)
• Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, Wahl GM, Belmonte JC Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature, 2009;460(7259):1140-4. 2009 [PMID: 19668186] (ICC, Mouse)
• Raya A, Rodriguez-Piza I, Guenechea G, Vassena R, Navarro S, Barrero MJ, Consiglio A, Castella M, Río P, Sleep E, Gonzalez F, Tiscornia G, Garreta E, Aasen T, Veiga A, Verma IM, Surralles J, Bueren J, Belmonte JC Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature, 2009;460(7251):53-9. 2009 [PMID: 19483674] (ICC, Human)
• Zhang D, Jiang W, Liu M, Sui X, Yin X, Chen S, Shi Y, Deng H Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res., 2009;19(4):429-38. 2009 [PMID: 19255591] (Flow Cytometry, Human)
• Conrad S, Renninger M, Hennenlotter J, Wiesner T, Just L, Bonin M, Aicher W, Buhring HJ, Mattheus U, Mack A, Wagner HJ, Minger S, Matzkies M, Reppel M, Hescheler J, Sievert KD, Stenzl A, Skutella T Generation of pluripotent stem cells from adult human testis. Nature, 2008;456(7220):344-9. 2008 [PMID: 18849962] (ICC, Human)
• Nakanishi M, Kurisaki A, Hayashi Y, Warashina M, Ishiura S, Kusuda-Furue M, Asashima M Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. FASEB J., 2009;23(1):114-22. 2009 [PMID: 18809738] (ICC, Human)
• Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood, 2007;111(4):1933-41. 2007 [PMID: 18042803] (ICC, Human)
• Cho CH, Parashurama N, Park EY, Suganuma K, Nahmias Y, Park J, Tilles AW, Berthiaume F, Yarmush ML Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure. FASEB J., 2007;22(3):898-909. 2007 [PMID: 17942827] (Flow Cytometry, Rat)
• Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12. 2006 [PMID: 16632596] (ICC, Human)

Bioinformatics

• Gene Symbol: FOXA2
• Uniprot:
  • Q9Y261()