SOD1/Cu-Zn SOD Antibody

Images

 
Western Blot: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Bovine ocular fluid. Antibody at 1:1000. Western blot image submitted by a verified customer review.
Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Analysis of Superoxide Dismutase 1 in FFPE human liver tissue using an isotype control (top) and NBP2-24915 (bottom) at 5 ug/ml.
Western Blot: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Analysis of SOD in liver lysate of 1) human, 2) mouse, and 3) rat using this antibody. 025 ug/ml.
Western Blot: SOD1/Cu-Zn SOD Antibody [NBP2-24915] - Human ocular fluid. Antibody at 1:1000. Western blot image submitted by a verified customer review.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

SOD1/Cu-Zn SOD Antibody Summary

Immunogen
The superoxide dismutase enzyme from bovine erythrocytes (CAS # 9054-89-1) was used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SOD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Western Blot 1 - 2 ug/ml
Reviewed Applications
Read 3 Reviews rated 5
using
NBP2-24915 in the following applications:

Publications
Read Publications using
NBP2-24915 in the following applications:

  • 1 publication
  • WB
    11 publications

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SOD1/Cu-Zn SOD Antibody

  • ALS
  • ALS1
  • amyotrophic lateral sclerosis 1 (adult)
  • Cu
  • Cu/Zn superoxide dismutase
  • CuZn SOD
  • Cu-Zn SOD
  • EC 1.15.1.1
  • homodimer
  • hSod1
  • indophenoloxidase A
  • Ipo1
  • IPOA
  • SOD
  • SOD, cytosolic
  • SOD, Soluble
  • SOD1
  • superoxide dismutase [Cu-Zn]
  • Superoxide dismutase 1
  • superoxide dismutase 1, soluble
  • Zn superoxide dismutase, EC 1.15.1.110superoxide dismutase, cystolic

Background

FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOD1/Cu-Zn SOD Antibody (NBP2-24915)(14)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: IHC-P, WB.


Filter By Application
IHC-P
(1)
WB
(11)
All Applications
Filter By Species
Human
(3)
Mouse
(6)
Rat
(3)
All Species
Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using NBP2-24915 Applications Species
Martinez-Martel I, Bai X, Batalle G, Pol O New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice Antioxidants (Basel, Switzerland) 2022-12-01 [PMID: 36552595] (WB, Mouse) WB Mouse
Lacy B, Rahman MS Interactive effects of high temperature and pesticide exposure on oxidative status, apoptosis, and renin expression in kidney of goldfish: Molecular and cellular mechanisms of widespread kidney damage and renin attenuation Journal of applied toxicology : JAT 2022-06-13 [PMID: 35698815]
Lacy B, Rahman MS, Rahman MS Potential mechanisms of Na+/K+-ATPase attenuation by heat and pesticides co-exposure in goldfish: role of cellular apoptosis, oxidative/nitrative stress, and antioxidants in gills Environmental science and pollution research international [PMID: 35352221]
Pouso-Vazquez E, Bai X, Batalle G et al. Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice Biochemical pharmacology 2022-03-08 [PMID: 35276215] (WB, Mouse) WB Mouse
Carmona-Rodriguez L, Martinez-Rey D, Martin-Gonzalez P et al. Superoxide Dismutase-3 Downregulates Laminin alpha5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling Cancers 2022-02-26 [PMID: 35267534] (WB, Human) WB Human
Pek E, Canbey Goret C, Hacivelioglu S et al. The immunohistochemical and histologic effects of contrast medium on uterus, fallopian tubes and ovaries, given during hysterosalpingography: rat study Journal of the Turkish German Gynecological Association 2020-12-04 [PMID: 32500677] (IHC-P, Rat) IHC-P Rat
Han J, Kim S, Ryu M et al. Chloramphenicol Mitigates Oxidative Stress by Inhibiting Translation of Mitochondrial Complex I in Dopaminergic Neurons of Toxin-Induced Parkinson s Disease Model Oxidative Medicine and Cellular Longevity 2019-08-26 [PMID: 31534621] (WB, Mouse) WB Mouse
Mishra P, Paital B, Jena S et al. Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NF kappa B/AKT/mTOR/KEAP1 signalling in rat heart Sci Rep 2019-05-15 [PMID: 31092832] (WB, Rat) WB Rat
Ghaffari, R;Di Bona, KR;Riley, CL;Richburg, JH; Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis PLoS ONE 2019-04-19 [PMID: 31002737] (WB, Mouse) WB Mouse
Millett CE, Phillips BE, Saunders EFH. The Sex-specific Effects of LPS on Depressive-like Behavior and Oxidative Stress in the Hippocampus of the Mouse Neuroscience 2018-12-14 [PMID: 30553795] (WB, Mouse) WB Mouse
Show All 14 Publications.

Reviews for SOD1/Cu-Zn SOD Antibody (NBP2-24915) (3) 53

Average Rating: 5
(Based on 3 reviews)
We have 3 reviews tested in 3 species: Human, Mouse, Bovine.

Reviews using NBP2-24915:
Filter by Applications
WB
(3)
All Applications
Filter by Species
Human
(1)
Mouse
(1)
Bovine
(1)
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Images Ratings Applications Species Date Details
Western Blot SOD1/Cu-Zn SOD NBP2-24915
Enlarge
5
reviewed by:
Ajay Ashok
WB Bovine 09/23/2020
View

Summary

ApplicationWestern Blot
Sample Testedocular fluid
SpeciesBovine
Lot03253462c2b-3

Comments

Commentsuse at a dilution of 1:1000
Western Blot SOD1/Cu-Zn SOD NBP2-24915
Enlarge
5
reviewed by:
Ajay Ashok
WB Human 09/23/2020
View

Summary

ApplicationWestern Blot
Sample Testedocular fluid
SpeciesHuman
Lot03253462c2b-3

Comments

Commentsuse at dilution 1:1000
Western Blot SOD1/Cu-Zn SOD NBP2-24915
Enlarge
5
reviewed by:
Wankeun Song
WB Mouse 01/12/2017
View

Summary

ApplicationWestern Blot
Sample TestedLiver
SpeciesMouse
Lot03253462C2B

Comments

CommentsN/A

Product General Protocols

View specific protocols for SOD1/Cu-Zn SOD Antibody (NBP2-24915): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

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FAQs for SOD1/Cu-Zn SOD Antibody (NBP2-24915) (0)

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Secondary Antibodies

 

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Bioinformatics Tool for SOD1/Cu-Zn SOD Antibody (NBP2-24915)

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Recent Reviews

5
5
3
4
0
3
0
2
0
1
0

Ajay Ashok
09/23/2020
Application: WB
Species: Bovine

Ajay Ashok
09/23/2020
Application: WB
Species: Human

Wankeun Song
01/12/2017
Application: WB
Species: Mouse

Bioinformatics

Gene Symbol SOD1
Uniprot