SOD1/Cu-Zn SOD Products

Antibodies
SOD1/Cu-Zn SOD Antibody
SOD1/Cu-Zn SOD Antibody
NBP2-24915
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC-P
Host: Rabbit Polyclonal
SOD1/Cu-Zn SOD Antibody
SOD1/Cu-Zn SOD Antibody
Species: Hu, Mu, Rt, Mk
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
SOD1/Cu-Zn SOD Antibody
SOD1/Cu-Zn SOD Antibody
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
Kits
SOD1/Cu-Zn SOD Assay Kit
SOD1/Cu-Zn SOD Assay Kit
KA0783
Species: Ma
Applications: Func
Lysates
SOD1/Cu-Zn SOD Overexpression ...
SOD1/Cu-Zn SOD Overexpression Lysa...
H00006647-T01
Species: Hu
Applications: WB
SOD1/Cu-Zn SOD Overexpression ...
SOD1/Cu-Zn SOD Overexpression Lysa...
NBL1-16332
Applications: WB
Proteins
Human SOD1/Cu-Zn SOD Protein
Human SOD1/Cu-Zn SOD Protein
NBP2-34940
Species: Hu
Applications: Func, PAGE
Human SOD1/Cu-Zn SOD His (N-T ...
Human SOD1/Cu-Zn SOD His (N-Term) ...
NBP2-34942
Species: Hu
Applications: Func, PAGE
Recombinant Human SOD1/Cu-Zn ...
Recombinant Human SOD1/Cu-Zn SOD P...
NBC1-18544
Species: Hu
Applications: PAGE
RNAi
SOD1/Cu-Zn SOD RNAi
SOD1/Cu-Zn SOD RNAi
H00006647-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.

Bioinformatics

Entrez Human
Mouse
Rat
Bovine
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Bovine
Product By Gene ID 6647
Alternate Names
  • Superoxide dismutase 1
  • SOD
  • hSod1
  • ALS
  • Zn superoxide dismutase, EC 1.15.1.110superoxide dismutase, cystolic
  • Cu
  • superoxide dismutase [Cu-Zn]
  • amyotrophic lateral sclerosis 1 (adult)
  • SOD, soluble
  • ALS1
  • indophenoloxidase A
  • EC 1.15.1.1
  • homodimer
  • IPOA
  • Cu/Zn superoxide dismutase
  • superoxide dismutase 1, soluble

Research Areas for SOD1/Cu-Zn SOD

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research
Mitochondrial Fusion Proteins
Neuronal Cell Markers
Neuroscience
Tumor Suppressors

Bioinformatics Tool for SOD1/Cu-Zn SOD

Discover related pathways, diseases and genes to SOD1/Cu-Zn SOD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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