SNX27 Antibody


Western Blot: SNX27 Antibody [NBP1-45283] - Analysis of SNX27 on mouse brain extracts.
Immunocytochemistry/ Immunofluorescence: SNX27 Antibody [NBP1-45283] - Detection of SNX27 (Green) in Hela cells using NBP1-45283. Nuclei (Blue) are counterstained using Hoechst 33258.
Immunohistochemistry: SNX27 Antibody [NBP1-45283] - IHC analysis of SNX27 in mouse bladder using DAB with hematoxylin counterstain.
Western Blot: SNX27 Antibody [NBP1-45283] - Analysis of SXN27 antibody in A. 293T + tagged SNX27 protein and B. 293T empty vector.
Simple Western: SNX27 Antibody [NBP1-45283] - Simple Western lane view shows a specific band for SNX27 in 0.5 mg/ml of Human Cerebellum (left) and Mouse Cerebellum (right) lysate. This experiment was performed under more

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, IHC-P
1 mg/ml

SNX27 Antibody Summary

Synthetic peptide made to an internal portion of human SNX27 (within residues 450-500). [Swiss-Prot# Q96L92]
Cytoplasm cytosol. Early endosome. Note: In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Predicted Species
Rat (100%), Bovine (100%), Zebrafish (100%)
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 30% glycerol
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
This SNX27 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin embedded sections and Western blot, where a band is seen at ~65 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.In Simple Western only 10-15 uL of the recommended dilution is used per data point.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
65 kDa
Control Peptide
SNX27 Peptide (NBP1-45283PEP)
Read Publication using
NBP1-45283 in the following applications:

  • WB
    1 publication

Reactivity Notes

Human and mouse. Predicted to react with rat, bovine and Zebrafish based on 100% sequence homology.

Alternate Names for SNX27 Antibody

  • KIAA0488MGC126873
  • methamphetamine-responsive transcript 1
  • MGC126871
  • MGC20471
  • MRT1
  • MY014
  • sorting nexin family member 27
  • sorting nexin-27


SNX27 belongs to SNX family of proteins which are unified by the presence of a phox domain, a phospholipid-binding motif, and are involved in intracellular sorting as well as trafficking. SNX27 was initially discovered in neocortex of rat as a developmentally regulated psychostimulant-inducible novel gene, which was named mrt1 (methamphetamine-responsive transcript 1), having two splice forms mrt1a (SNX27a) and mrt1b (SNX27b) that vary only in their C-terminal ends. In SNX family, SNX27 is the only SNX member containing a PDZ domain and it interact with the PDZ-bm of a few membrane proteins through its PDZ domain to regulate their intracellular sorting. SNX27 modulates the early endosomal trafficking of 5-HT4(a)R [5-hydroxytryptamine type-4(a) receptor], Kir3 (G protein-gated potassium) channels, NR2C (N-methyl-D-aspartate receptor 2C) etc., and has also been suggested to facilitate efficient recycling of beta2AR/beta2-adrenoreceptor to the plasma membranes.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, PEP-ELISA
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, IP, PLA
Species: Hu, Mu, Rt
Applications: WB, IHC
Species: Hu, Mu, Rt, Mk
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, S-ELISA
Species: Hu, Mu, Rt, In, Pm
Applications: WB, ChIP, B/N, Flow, ICC/IF, IHC, IHC-Fr, IP
Species: Hu
Applications: IHC
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Bt, Bv, Ca, Eq, GP, Ha, Rb
Applications: IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Bovine, Rat, Zebrafish
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P

Publications for SNX27 Antibody (NBP1-45283)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Filter By Application
All Applications
Filter By Species
All Species

Reviews for SNX27 Antibody (NBP1-45283) (0)

There are no reviews for SNX27 Antibody (NBP1-45283). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

View specific protocols for SNX27 Antibody (NBP1-45283): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SNX27 Antibody (NBP1-45283) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-45283AF405
Alexa Fluor (R) 488 Labeled NBP1-45283AF488
Alexa Fluor (R) 647 Labeled NBP1-45283AF647
Alexa Fluor (R) 700 Labeled NBP1-45283AF700
Biotin Labeled NBP1-45283B
DyLight 405 Labeled NBP1-45283V
DyLight 488 Labeled NBP1-45283G
DyLight 550 Labeled NBP1-45283R
DyLight 650 Labeled NBP1-45283C
FITC Labeled NBP1-45283F
HRP Labeled NBP1-45283H

Additional SNX27 Antibody Products

SNX27 NBP1-45283

Related Products by Gene

Bioinformatics Tool for SNX27 Antibody (NBP1-45283)

Discover related pathways, diseases and genes to SNX27 Antibody (NBP1-45283). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for SNX27 Antibody (NBP1-45283)

Discover more about diseases related to SNX27 Antibody (NBP1-45283).

Pathways for SNX27 Antibody (NBP1-45283)

View related products by pathway.

PTMs for SNX27 Antibody (NBP1-45283)

Learn more about PTMs related to SNX27 Antibody (NBP1-45283).

Research Areas for SNX27 Antibody (NBP1-45283)

Find related products by research area.

Blogs on SNX27.

Spotlight on SNX27 Antibodies
Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol SNX27

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-45283 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

SMARCD3 Antibody (1G6)
SMARCD3 Antibody (1G6)
SMARCD3 Antibody (1G6)
SNX27 Peptide