SNX27 Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, ZeSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

SNX27 Antibody [Biotin] Summary

Immunogen
Synthetic peptide made to an internal portion of human SNX27 (within residues 450-500). [Swiss-Prot# Q96L92]
Localization
Cytoplasm cytosol. Early endosome. Note: In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Predicted Species
Rat (100%), Zebrafish (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SNX27
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This SNX27 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin embedded sections and Western blot, where a band is seen at ~65 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Human and mouse. Predicted to react with rat, bovine and Zebrafish based on 100% sequence homology.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SNX27 Antibody [Biotin]

  • KIAA0488MGC126873
  • methamphetamine-responsive transcript 1
  • MGC126871
  • MGC20471
  • MRT1
  • MY014
  • sorting nexin family member 27
  • sorting nexin-27

Background

SNX27 is a member of the sorting nexin family of proteins that is involved in endocytic trafficking. In T lymphocytes, SNX27 participates in the endocytic recycling pathway. It has also been shown that the single PDZ domain of SNX27 binds directly to the PDZ binding motif of Kir3 channels leading to their downregulationhas also been shown to bind the Kir family of channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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SNX27 NBP1-45283B

Bioinformatics Tool for SNX27 Antibody (NBP1-45283B)

Discover related pathways, diseases and genes to SNX27 Antibody (NBP1-45283B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for SNX27 Antibody (NBP1-45283B)

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PTMs for SNX27 Antibody (NBP1-45283B)

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Research Areas for SNX27 Antibody (NBP1-45283B)

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Blogs on SNX27.

Spotlight on SNX27 Antibodies
Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids...  Read full blog post.

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Bioinformatics

Gene Symbol SNX27