SNX27 Antibody [HRP]

• Reactivity: Hu, Mu, Rt, Bv, Ze
• Applications: WB, ICC/IF, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: HRP

SNX27 Antibody [HRP] Summary

• Immunogen: Synthetic peptide made to an internal portion of human SNX27 (within residues 450-500). [Swiss-Prot# Q96L92]
• Localization: Cytoplasm cytosol. Early endosome. Note: In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
• Predicted Species: Bovine (100%), Zebrafish (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SNX27
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.
• Readout System:
  • NovaLume Plus Chemiluminescent Reagent LUM-555

Reactivity Notes

Predicted to react with rat, bovine and Zebrafish based on 100% sequence homology. Use in Rat reported in scientific literature (PMID:32413996).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SNX27 Antibody [HRP]

• KIAA0488MGC126873
• methamphetamine-responsive transcript 1
• MGC126871
• MGC20471
• MRT1
• MY014
• sorting nexin family member 27
• sorting nexin-27

Background

SNX27 is a member of the sorting nexin family of proteins that is involved in endocytic trafficking. In T lymphocytes, SNX27 participates in the endocytic recycling pathway. It has also been shown that the single PDZ domain of SNX27 binds directly to the PDZ binding motif of Kir3 channels leading to their downregulationhas also been shown to bind the Kir family of channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNX27