Western Blot: Xrn1 Antibody [NB500-191] - Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit antiXRN1 antibody used for WB at 0.2 ug/ml. Detection: ...read more
Immunoprecipitation: Xrn1 Antibody [NB500-191] - Detection of human XRN1 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and HEK293T ...read more
The immunogen recognized by this antibody maps to a region between residue 1650 and the C-terminus (residue 1706) of human 5'-3' Exoribonuclease 1 using the numbering given in TrEMBL entry Q6MZS8 (GeneID 54464).
Immunogen affinity purified
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SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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