Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
100 ug in 100 ul PBS
0.05% Sodium Azide
Protein A purified
Western Blot 1:2000
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NBP2-27182 in the following applications:
The amino acid sequence used as immunogen is 100% homologous in human, horse and dog, 94% in mouse and 89% homologous in rat SNAIL2 (SNAI2). Mouse reactivity reported in scientific literature (PMID: 26240017)
Alternate Names for Slug Antibody
Neural crest transcription factor Slug
Protein snail homolog 2
slug homolog, zinc finger protein (chicken)
SLUGzinc finger protein
snail homolog 2 (Drosophila)
zinc finger protein SNAI2
Zinc finger transcription factor SNAIL2 (SNAI2, Slug) is found to have some functional significance in formation of axis and mesoderm in Drosophila. SNAIL2 and Twist act as negative regulators of level of Cerberus RNA, which encodes a Nodal, bone morphogenic protein (BMP) and WNT inhibitor. mRNA levels of SNAIL2 are regulated by NF-kappaB in early embryo. Partial functional redundancy between Twist, SNAIL2 and SNAIL1 may be developmentally and physiologically significant given their roles in the induction and progression of various forms of epithelial-mesenchymal transition and the metastasis of cancer cells, the regulation of apoptosis, and their ability to generate stem cell like behaviors in immortalized human epithelial cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.