Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P
Host: Mouse Monoclonal
Species: Hu, Mu, Ca, Eq
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
SLUG encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
6591 |
Alternate Names |
- MGC10182
- Neural crest transcription factor Slug
- Protein snail homolog 2
- slug homolog, zinc finger protein (chicken)
- SLUGH
- SLUGzinc finger protein
- snail 2
- snail homolog 2 (Drosophila)
- WS2D
- zinc finger protein SNAI2
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Bioinformatics Tool for Slug
Discover related pathways, diseases and genes to Slug. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
Related Slug Blog Posts
Check out the latest blog posts on Slug.
Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a... Read more.
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Read more.
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CD63: is it pro-metastatic or anti-metastatic?
CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several cellular signaling cascades along with acting as TIMP1 receptor. It is expressed by activated platelets, monocytes,... Read more.
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Read more Slug related blogs.