Periostin/OSF-2 Antibody


Western Blot: Periostin/OSF-2 Antibody [NBP1-30042] - Rat lung lysate showing specific immunolabeling of the ~ 93 kDa periostin protein doublet.
Immunohistochemistry: Periostin/OSF-2 Antibody [NBP1-30042] - Analysis of periostin in rabbit periosteum. Image courtesy of product review submitted by Samer Zaky.

Product Details

Reactivity Hu, Mu, Rt, Ch, RbSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
0.5 mg/ml

Order Details

Periostin/OSF-2 Antibody Summary

Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively-spliced exons.
Specific for the ~93 kDa periostin doublet in mouse lung extract. Consistent with the fact that this antibody is made against an alternatively spliced region of periostin, this antibody recognizes only the largest two of the three forms of periostin recognized on Western blots by the Pan periostin antibody and also shows a distinctive staining pattern by immunohistochemistry. The antibody works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90 degrees C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
No Preservative
0.5 mg/ml
Immunogen affinity purified


Application Notes
For IHC-P antigen retrieval protocol (incubate slides for 20 minutes at 90 degrees C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20). Use in Rabbit reported in customer review. Immunocytochemistry/Immunofluorescence was reported in scientific literature. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
93 kDa
Reviewed Applications
Read 2 Reviews rated 4
NBP1-30042 in the following application:

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NBP1-30042 in the following applications:

Reactivity Notes

Expected reactivity to all mammalian and avian species. Based on customer review rabbit reacts.

Alternate Names for Periostin/OSF-2 Antibody

  • Fasciclin I-like
  • MGC119510
  • MGC119511
  • OSF2
  • OSF-2
  • OSF-2osteoblast specific factor 2 (fasciclin I-like)
  • OSF2periodontal ligament-specific periostin
  • Osteoblast-specific factor 2
  • periostin isoform thy2
  • periostin isoform thy4
  • periostin isoform thy6
  • periostin isoform thy8
  • periostin
  • periostin, osteoblast specific factor
  • PNRP11-412K4.1
  • TRIF52


Periostin is a disulfide linked 90 kDa 811 amno acid protein originally isolated as a osteoblastspecific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1(TGFbeta1) and bone morphogenetic protein (BMP)-2. OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Periostin/OSF-2 Antibody (NBP1-30042)(7)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: ICC/IF, IHC-P, WB.

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Showing Publications 1 - 7 of 7.
Publications using NBP1-30042 Applications Species
Kanisicak O, Khalil H, Ivey MJ et al. Genetic lineage tracing defines myofibroblast origin and function in the injured heart Nat Commun 2016 Jul 24 [PMID:27447449] (WB) WB
Murphy S, Dowling P, Zweyer M et al. Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy J Proteomics Mar 4 2016 12:00AM [PMID:26961938] (WB, Mouse) WB Mouse
Murphy S, Henry M, Meleady P et al. Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy Biology (Basel). 2015 Jun 13 [PMID:26067837] (WB, Mouse) WB Mouse
Holland A, Dowling P, Meleady P et al. Label-free mass spectrometric analysis of the mdx-4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy-related fibrosis Proteomics 2015 Mar 03 [PMID:25737063] (WB, Mouse) WB Mouse
Nolte Zadeh-Khorasani M, Safarov O et al. Oxazolone and ethanol induce colitis in non-obese diabetic-severe combined immunodeficiency interleukin-2RGamma(null) mice engrafted with human peripheral blood mononuclear cells Clin Exp Immunol. 2013 May [PMID:23574330] (IHC-P, Mouse) IHC-P Mouse
Casanova JC, Travisano S, de la Pompa JL. Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis 2013 Jan [PMID:23097346] (IHC-P, ICC/IF, Mouse) IHC-P, ICC/IF Mouse
Lorts A, Schwanekamp JA, Baudino TA et al. Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-? pathway Proc Natl Acad Sci U S A 2012 Jun 18 [PMID:22711826] (WB, Mouse) WB Mouse

Reviews for Periostin/OSF-2 Antibody (NBP1-30042) (2) 42

Average Rating: 4
(Based on 2 reviews)
We have 2 reviews tested in 2 species: Mouse, Other.
We have 2 review tested in 1 application: IHC.

Reviews using NBP1-30042:
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Images Ratings Applications Species Date Details
reviewed by:
Mouse 12/23/2014


Sample TestedSee PMID 23574330
Special ApplicationsPublished in PMID 23574330
Immunohistochemistry Periostin/OSF-2 NBP1-30042
reviewed by:
IHC Other 03/15/2011


Sample TestedRabbit periosteum
CommentsThe antibody works pretty well for rabbit periosteum in paraffin IHC. I performed tripsin Ag retrieval.


CommentsThe antibody works pretty well for rabbit periosteum in paraffin IHC. I performed tripsin Ag retrieval.

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Gene Symbol POSTN

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