Pericentrin Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: Pericentrin Antibody [NBP1-87771] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome. Antibody staining is shown in green.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Pericentrin Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Pericentrin Antibody - BSA Free (NBP1-87771) is a polyclonal antibody validated for use in ICC/IF. Anti-Pericentrin Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: MLDLSSWSSPEVLRKDWTLEPWPSLPVTPHSGALSLCSADTSLGDRADTSLPQTQGPGLLCSPGVSAAALALQWAESPPADDHHVQRTAVEKDVEDFITTSFDSQETLSSPPPGLEGKADRSEKSDGSG
• Marker: Centrosome Marker
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCNT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Pericentrin Protein (NBP1-87771PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Pericentrin Antibody - BSA Free

• Kendrin
• KIAA0402
• MOPD2
• PCN
• PCNT2pericentrin B
• PCNTB
• pericentrin 2 (kendrin)
• pericentrin
• pericentrin, kendrin (KIAA0402)10KENPCTN2
• pericentrin-2
• pericentrin-380
• pericentrin-B
• SCKL4kendrin

Background

Pericentrin is encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Pericentrin Antibody (NBP1-87771)(2)

Publications using NBP1-87771

• Izumi H, Li Y, Yasunami M et al. Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells Stem cells (Dayton, Ohio) 2022-03-14 [PMID: 35284915]
• Izumi H, Li Y, Shibaki M et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region Sci Rep 2019-02-19 [PMID: 30783186] (ICC/IF, Human)

Bioinformatics

• Gene Symbol: PCNT