Cytochrome P450 1A1/1A2 Antibody (MC1)

Images

 
Immunocytochemistry/ Immunofluorescence: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis of Cytochrome P450 1A1/1A2 (green) showing staining in the cytoplasm and membrane of COS-7 cells. Formalin-fixed ...read more
Immunohistochemistry-Paraffin: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis showing positive staining in the cytoplasm and membrane of Mouse liver tissue (right) compared with a negative control in ...read more
Immunocytochemistry/ Immunofluorescence: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis of Cytochrome P450 1A1/1A2 (green) showing staining in the cytoplasm and membrane of HT29 cells. Formalin-fixed ...read more
Immunocytochemistry/ Immunofluorescence: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis of Cytochrome P450 1A1/1A2 (green) showing staining in the cytoplasm and membrane of HeLa cells. Formalin-fixed ...read more
Immunohistochemistry-Paraffin: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis showing staining in the cytoplasm and membrane of rat liver tissue (right) compared with a negative control without primary ...read more
Immunohistochemistry-Paraffin: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis showing positive staining in the membrane of Human prostate tissue (right) compared with a negative control in the absence ...read more
Immunohistochemistry-Paraffin: Cytochrome P450 1A1/1A2 Antibody (MC1) [NB100-74398] - Analysis showing positive staining in the cytoplasm and membrane of Human liver tissue (right) compared with a negative control in ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clone
MC1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Cytochrome P450 1A1/1A2 Antibody (MC1) Summary

Immunogen
3-methylcholanthrene induced rat cytochrome P450 protein.
Specificity
Detects Cytochrome P450 1A1 (Gene ID: 1543, UniProt P04798) and Cytochrom P450 1A2 (Gene ID: 1544, UniProt: P05177) from human samples.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CYP1A1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunocytochemistry/Immunofluorescence 1:20 - 1:200
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
WB: Detects an approx. 58 kDa protein.
Theoretical MW
58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Cytochrome P450 1A1 Overexpression Lysate
Reviewed Applications
Read 1 Review rated 3
using
NB100-74398 in the following applications:

Publications
Read Publication using
NB100-74398 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for Cytochrome P450 1A1/1A2 Antibody (MC1)

  • AHH
  • AHRR
  • aryl hydrocarbon hydroxylase
  • CP11
  • CYP1
  • CYPIA1
  • cytochrome P1-450, dioxin-inducible
  • cytochrome P450 1A1
  • Cytochrome P450 form 6
  • cytochrome P450, family 1, subfamily A, polypeptide 1
  • Cytochrome P450-C
  • Cytochrome P450-P1
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • P1-450
  • P450-C
  • P450DX
  • subfamily I (aromatic compound-inducible), polypeptide 1
  • xenobiotic monooxygenase

Background

Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ICC/IF, IHC, IHC-P

Publications for Cytochrome P450 1A1/1A2 Antibody (NB100-74398)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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Filter By Species
Human
(1)
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Review for Cytochrome P450 1A1/1A2 Antibody (NB100-74398) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB100-74398:
Filter by Applications
WB
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
WB Human 12/22/2014
View

Summary

ApplicationWestern Blot
Sample TestedSee PMID 24892140
SpeciesHuman

Blocking

Blocking DetailsSee PMID 24892140

Details

Detection NotesSee PMID 24892140

Comments

CommentsIndependent review from antibodyresource.comPublished in PMID 24892140.

Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Cytochrome P450 1A1/1A2 Antibody (NB100-74398) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Cytochrome P450 1A1/1A2 Antibody (NB100-74398)

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Recent Reviews

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1
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Anonymous
12/22/2014
Application: WB
Species: Human

Bioinformatics

Gene Symbol CYP1A1
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