Nbs1 Blocking Peptide

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Product Details

Summary
Reactivity HuSpecies Glossary
Concentration
1.0 mg/ml

Order Details

Nbs1 Blocking Peptide Summary

Protein/Peptide Type
Blocking Peptide
Gene
NBN

Applications/Dilutions

Application Notes
This peptide is useful as a blocking peptide for NBP1-06609.

For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Peptide dissolved in dH2O. Contains no BSA.
Preservative
No Preservative
Concentration
1.0 mg/ml

Alternate Names for Nbs1 Blocking Peptide

  • ATV
  • AT-V1
  • AT-V2
  • Cell cycle regulatory protein p95
  • FLJ10155
  • MGC87362
  • NBN
  • Nbs1
  • NBS1P95
  • NBSNijmegen breakage syndrome protein 1
  • Nibrin
  • Nijmegen breakage syndrome 1 (nibrin)
  • p95 protein of the MRE11/RAD50 complex
  • p95

Background

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for Nbs1 Peptide (NBP1-06609PEP) (0)

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Other Available Formats

Additional Nbs1 Products

Bioinformatics Tool for Nbs1 Peptide (NBP1-06609PEP)

Discover related pathways, diseases and genes to Nbs1 Peptide (NBP1-06609PEP). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Nbs1 Peptide (NBP1-06609PEP)

Discover more about diseases related to Nbs1 Peptide (NBP1-06609PEP).
 

Pathways for Nbs1 Peptide (NBP1-06609PEP)

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PTMs for Nbs1 Peptide (NBP1-06609PEP)

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Research Areas for Nbs1 Peptide (NBP1-06609PEP)

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Blogs on Nbs1.

The MRE11 Complex and DNA Damage Response
The maintenance of genome stability depends on the DNA damage response (DDR) which is a complex signaling network including cell cycle checkpoints, DNA repair and damage tolerance pathways. The DDR complex has the ability to sense DNA damage and tra...  Read full blog post.

NBS1: The DNA Repair Trigger
NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, ch...  Read full blog post.

NBS1: DNA Repair Trigger
NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, ch...  Read full blog post.

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Bioinformatics

Gene Symbol NBN