Rad50 Products

Rad50 Antibody
Rad50 Antibody
Species: Hu, Mu, Ha
Applications: WB, Simple Western, IP, ICC/IF (-)
Host: Rabbit Polyclonal
Rad50 Antibody
Rad50 Antibody
Species: Hu
Applications: WB, Simple Western, IP
Host: Rabbit Polyclonal
Rad50 Overexpression Lysate ( ...
Rad50 Overexpression Lysate (Native)
Species: Hu
Applications: WB
Rad50 Recombinant Protein Ant ...
Rad50 Recombinant Protein Antigen
Species: Hu
Applications: AC
Rad50 RNAi
Rad50 RNAi
Species: Hu
Applications: RNAi, RNAi SP
Rad50 RNAi
Rad50 RNAi
Species: Hu
Applications: RNAi, RNAi SP


Rad50 is a 153kDa protein that associates with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, the complex translocates to the nucleus of damaged cells, binds DNA, and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. Overall, Rad50 is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination.


Entrez Human
Uniprot Human
Product By Gene ID 10111
Alternate Names
  • EC
  • RAD502
  • EC 3.6.3
  • RAD50 (S. cerevisiae) homolog
  • EC
  • RAD50-2
  • hRAD50
  • EC 3.6
  • hRad50
  • DNA repair protein RAD50
  • RAD50 homolog (S. cerevisiae)

Research Areas for Rad50

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cell Cycle and Replication
Checkpoint signaling
Chromatin Research
DNA Double Strand Break Repair
DNA Repair
Homologous Recombination
Non-homologous end-joining

Bioinformatics Tool for Rad50

Discover related pathways, diseases and genes to Rad50. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related Rad50 Blog Posts

Check out the latest blog posts on Rad50.
RAD50 and DNA Damage Response
DNA repair protein RAD50 is a component of the MRN complex (Mre11-RAD50-Nbs1) responsible for DNA double strand break (DSB) repair. DSBs are caused by ionizing radiation, certain chemotherapy drugs, metabolic reactive oxygen species (ROS), replication...    Read more.
The MRE11 Complex and DNA Damage Response
The maintenance of genome stability depends on the DNA damage response (DDR) which is a complex signaling network including cell cycle checkpoints, DNA repair and damage tolerance pathways. The DDR complex has the ability to sense DNA damage and tra...    Read more.
Read more Rad50 related blogs.