Species: Hu, Mu
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: ICC/IF, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, Func, ICC/IF, IP, ChIP
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
5932 |
| Alternate Names |
- CtBP-interacting protein
- CtIP
- DNA endonuclease RBBP8
- EC 3.1
- RBBP-8
- retinoblastoma binding protein 8
- Retinoblastoma-binding protein 8
- Retinoblastoma-interacting protein and myosin-like
- RIMSAE2
- Sporulation in the absence of SPO11 protein 2 homolog
|
