Nbs1 Products

Antibodies
Lysates
Nbs1 Overexpression Lysate (N ...
Nbs1 Overexpression Lysate (Native)
NBL1-13497
Applications: WB
Proteins
Nbs1 Peptide
Nbs1 Peptide
NBP1-06705PEP
Species: Hu
Applications: WB, PEP-ELISA
Nbs1 Peptide
Nbs1 Peptide
NBP1-06609PEP
Species: Hu
Nbs1 Partial Recombinant Prot ...
Nbs1 Partial Recombinant Protein
H00004683-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Nbs1 RNAi
Nbs1 RNAi
H00004683-R02
Species: Hu
Applications: RNAi, RNAi SP
Nbs1 RNAi
Nbs1 RNAi
H00004683-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Nibrin (NBS1 or NBN) is a member of the hMre11/hRad50 double-strand break repair complex, and is expressed ubiquitously and with highest levels in the testis. The hMre11/hRad50 protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. Antibody research on Nibrin has revealed a direct molecular link between double-strand break repair and cell cycle checkpoint functions, making NBS1 antibodies useful tools for research in both areas.

Bioinformatics

Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 4683
Alternate Names
  • p95 protein of the MRE11/RAD50 complex
  • Nijmegen breakage syndrome 1 (nibrin)
  • ATV
  • MGC87362
  • AT-V2
  • FLJ10155
  • AT-V1
  • NBS1P95
  • NBSNijmegen breakage syndrome protein 1
  • Cell cycle regulatory protein p95
  • nibrin

Bioinformatics Tool for Nbs1

Discover related pathways, diseases and genes to Nbs1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Nbs1 Blog Posts

Check out the latest blog posts on Nbs1.
The MRE11 Complex and DNA Damage Response
The maintenance of genome stability depends on the DNA damage response (DDR) which is a complex signaling network including cell cycle checkpoints, DNA repair and damage tolerance pathways. The DDR complex has the ability to sense DNA damage and tra...    Read more.
NBS1: The DNA Repair Trigger
NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, ch...    Read more.
NBS1: DNA Repair Trigger
NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, ch...    Read more.
Read more Nbs1 related blogs.