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NBS1

The MRE11 Complex and DNA Damage Response

Tags: 
DNA damage response
DRR
MRE11
MRE11 antibodies
MRE11 antibody
NBS1
NBS1 antibodies
NBS1 antibody
RAD50
RAD50 antibodies
RAD50 antibody

NBS1: The DNA Repair Trigger

NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, chemotherapy drugs, metabolic ROS, replication errors, programmed enzymatic activities during meiosis/V(D)J recombination, etc.

Tags: 
Cancer
DNA Repair
DSB
NBS1
NBS1 antibodies
NBS1 antibody
Nijmegen breakage syndrome protein 1

NBS1: DNA Repair Trigger

NBS1 (Nijmegen breakage syndrome protein 1) is a component of the MRN complex (Mre11-Rad50-Nbs1) that plays important role in detecting DNA double strand breaks (DSBs) and triggering the downstream cascade. DSBs can be caused by ionizing radiation, chemotherapy drugs, metabolic ROS, replication errors, programmed enzymatic activities during meiosis/V(D)J recombination, etc.

Tags: 
NBS1
NBS1 antibodies
NBS1 antibody
NBS1 protein
Nijmegen breakage syndrome protein 1