ATR Products

Antibodies
ATR Antibody
ATR Antibody
Species: Hu, Mu
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
ATR Antibody [Unconjugated]
ATR Antibody [Unconjugated]
AF4717
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Proteins
Recombinant Human ATR Protein ...
Recombinant Human ATR Protein
H00000545-Q01
Species: Hu
Applications: WB, ELISA, PA
ATR Blocking Peptide
ATR Blocking Peptide
NBP1-77232PEP
Species: Hu
Applications: AC
RNAi
ATR RNAi
ATR RNAi
H00000545-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

Ataxia Telangiectasia Mutated (ATM) and Rad3- related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 545
Alternate Names
  • FRAP-related protein 1
  • serine/threonine-protein kinase ATR
  • Ataxia telangiectasia and Rad3-related protein
  • Rad3 related protein
  • SCKL1
  • protein kinase ATR
  • MEC1
  • SCKLMEC1, mitosis entry checkpoint 1, homolog
  • FRP1FRAP-related protein-1
  • EC 2.7.11.1
  • ataxia telangiectasia and Rad3 related

Research Areas for ATR

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair
Immunology
p53 Pathway
Virology, Bacteria and Parasites

Bioinformatics Tool for ATR

Discover related pathways, diseases and genes to ATR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ATR Blog Posts

Check out the latest blog posts on ATR.
Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...    Read more.
The recent relationship of BRCA1 and 53BP1
The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...    Read more.
Read more ATR related blogs.