Isocitrate Dehydrogenase 1/IDH1 Antibody (IDH1/1152) [Biotin]

Images

 
There are currently no images for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC-P
Clone
IDH1/1152
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Isocitrate Dehydrogenase 1/IDH1 Antibody (IDH1/1152) [Biotin] Summary

Immunogen
Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein
Localization
Cytoplasmic & Nuclear
Specificity
It recognizes a 45kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IDH1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.
Readout System
Control
Isocitrate Dehydrogenase 1/IDH1 Lysate (NBP2-64819)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Isocitrate Dehydrogenase 1/IDH1 Antibody (IDH1/1152) [Biotin]

  • Cytosolic NADP-isocitrate dehydrogenase
  • EC 1.1.1.42
  • IDCD
  • IDH
  • IDH1
  • IDP
  • IDPC
  • isocitrate dehydrogenase [NADP] cytoplasmic
  • isocitrate dehydrogenase 1 (NADP+), soluble
  • Isocitrate Dehydrogenase 1
  • NADP(+)-specific ICDH
  • NADP-dependent isocitrate dehydrogenase, cytosolic
  • NADP-dependent isocitrate dehydrogenase, peroxisomal
  • Oxalosuccinate decarboxylase
  • PICD

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-22166
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB200-103
Species: Hu, Mu, Rt, Ye, Xp(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC
NB100-168
Species: Hu, Mu(-)
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P, CyTOF-ready, Flow-IC
AF231
Species: Hu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ELISA(Sta)
NB110-61646
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NBP2-42210
Species: Hu
Applications: WB, Flow, IHC, IHC-P
NBP2-67429
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP2-32104
Species: Hu
Applications: WB, IHC, IHC-P, IP
NBP2-02541
Species: Hu, Pm
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-56271
Species: Hu
Applications: WB, ICC/IF
NBP1-32259
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-32398
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-89559
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-85871
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-87069
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, KD
NB120-13888
Species: Hu, Mu
Applications: WB, ChIP, Flow, ICC/IF, IHC-P, CyTOF-ready, IHC-WhMt
NBP1-26612
Species: Hu
Applications: IP (-), WB
NBP2-45978
Species: Hu
Applications: WB, Flow, IHC
NB600-1438
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IP
NBP2-47744B
Species: Hu
Applications: WB, IHC-P

Publications for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B) (0)

There are no publications for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B) (0)

There are no reviews for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Bioinformatics Tool for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B)

Discover related pathways, diseases and genes to Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B)

Discover more about diseases related to Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B).
 

Pathways for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B)

View related products by pathway.

PTMs for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B)

Learn more about PTMs related to Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B).
 

Research Areas for Isocitrate Dehydrogenase 1/IDH1 Antibody (NBP2-47744B)

Find related products by research area.

Blogs on Isocitrate Dehydrogenase 1/IDH1

There are no specific blogs for Isocitrate Dehydrogenase 1/IDH1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Isocitrate Dehydrogenase 1/IDH1 Antibody (IDH1/1152) [Biotin] and receive a gift card or discount.

Bioinformatics

Gene Symbol IDH1