G9a/EHMT2 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: IHC, IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

G9a/EHMT2 Antibody [mFluor Violet 450 SE] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1160 and the C-terminus (residue 1210) of human G9A (Euchromatic Histone-Lysine N-methyltransferase 2) using the numbering given in entry NP_006700.2 (GeneID 10919).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EHMT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-40825. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for G9a/EHMT2 Antibody [mFluor Violet 450 SE]

• ankyrin repeat-containing protein
• BAT8
• C6orf30
• chromosome 6 open reading frame 30
• DKFZp686H08213
• EC 2.1.1.-
• EC 2.1.1.43
• EHMT2
• euchromatic histone-lysine N-methyltransferase 2HLA-B-associated transcript 8
• FLJ35547
• G9A histone methyltransferase
• G9a
• G9AEm:AF134726.3
• H3-K9-HMTase 3
• Histone H3-K9 methyltransferase 3
• histone-lysine N-methyltransferase, H3 lysine-9 specific 3
• HLA-B associated transcript 8
• KMT1CNG36/G9a
• Lysine N-methyltransferase 1C
• NG36
• Protein G9a

Background

G9A antibody contains ankyrin repeats, suggesting involvement in intracellular protein-protein interaction. G9A is a histone methyltransferase that preferentially methylates Lys-9 of histone H3 and Lys-27 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. G9A is probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EHMT2