Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Neat whole antisera
0.05% Sodium Azide
Alternate Names for SETD7/9 Antibody
histone H3-lysine 4-specific methyltransferase
histone-lysine N-methyltransferase SETD7
KIAA1717SET domain-containing protein 7
Lysine N-methyltransferase 7
SET domain containing (lysine methyltransferase) 7
SET7/9Histone H3-K4 methyltransferase SETD7
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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