GLP/EHMT1 Antibody (B0422) [Unconjugated]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IP, DirELISA
Clone
B0422
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23005

Order Details

GLP/EHMT1 Antibody (B0422) [Unconjugated] Summary

Immunogen
Recombinant mouse GLP/EHMT1
aa 134-234
Specificity
This antibody specifically recognizes mouse GLP and cross-reacts with human GLP. Not yet tested in other species.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
EHMT1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Direct ELISA
Reviewed Applications
Read 3 Reviews rated 4.3
using
PP-B0422-00 in the following applications:

Publications
Read Publications using
PP-B0422-00 in the following applications:

Packaging, Storage & Formulations

Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GLP/EHMT1 Antibody (B0422) [Unconjugated]

  • DEL9q34
  • EC 2.1.1.-
  • EC 2.1.1.43
  • EHMT1
  • euchromatic histone-lysine N-methyltransferase 1H3-K9-HMTase 5
  • Eu-HMTase1
  • Eu-HMTase1DEL9q34
  • EUHMTASE1FP13812
  • FLJ12879
  • G9a-like protein 1
  • GLP
  • GLP1
  • H3 lysine-9 specific 5
  • KIAA1876euchromatic histone methyltransferase 1
  • KMT1D
  • KMT1DDKFZp667M072
  • Lysine N-methyltransferase 1D

Background

Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic marker for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regions and is essential for murine embryogenesis. There is a single G9a-related methyltransferase in mammals, called GLP/Eu-HMTase1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GLP/EHMT1 Antibody (PP-B0422-00)(7)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 3 applications: IHC - Not specified, IP, WB.


Filter By Application
IHC - Not specified
(2)
IP
(2)
WB
(3)
All Applications
Filter By Species
Human
(4)
Mouse
(2)
Rat
(1)
All Species
Showing Publications 1 - 7 of 7.
Publications using PP-B0422-00 Applications Species
Shengjiang Tu Co-repressor CBFA2T2 regulates pluripotency and germline development Nature, 2016;534(7607):387-90. 2016 [PMID: 27281218] (IHC - Not specified,, Mouse) IHC - Not specified Mouse
Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, Kaur J, Kuhlmann T, Zhang W, Slesinger P, Casaccia P Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci, 2015;35(1):352-65. 2015 [PMID: 25568127] (IP,, Rat) IP Rat
Loh S, Ng W, Yeo K, Lim Y, Ea C Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment. PLoS ONE, 2014;9(7):e103915. 2014 [PMID: 25079219] (WB,, Human) WB Human
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill T, Jin J, Hebert J, Sauvageau G, Humphries R, Rossi F The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes Dev, 2014;28(4):317-27. 2014 [PMID: 24532712] (WB,, Human) WB Human
Ea C, Hao S, Yeo K, Baltimore D EHMT1 protein binds to nuclear factor-kappaB p50 and represses gene expression. J Biol Chem, 2012;287(37):31207-17. 2012 [PMID: 22801426] (IP,, Human) IP Human
Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature, 2011;471(7339):513-7. 2011 [PMID: 21430779] (WB,, Human) WB Human
Schaefer A, Sampath SC, Intrator A Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron, 2009;64(5):678-91. 2009 [PMID: 20005824] (IHC - Not specified,, Mouse) IHC - Not specified Mouse

Reviews for GLP/EHMT1 Antibody (PP-B0422-00) (3) 4.33

Average Rating: 4.3
(Based on 3 reviews)
We have 3 reviews tested in 1 species: Human.

Reviews using PP-B0422-00:
Filter by Applications
ICC
(1)
IP
(1)
WB
(1)
All Applications
Filter by Species
Human
(3)
All Species
Images Ratings Applications Species Date Details
Immunocytochemistry GLP/EHMT1 PP-B0422-00
Enlarge
reviewed by:
Anonymous
ICC Human 07/11/2017
View

Summary

ApplicationImmunocytochemistry
Sample TestedHuman Dermal Microvascular Endothelial cells - Paraformaldehyde fixed cells
SpeciesHuman
LotA-2
Immunoprecipitation GLP/EHMT1 PP-B0422-00
Enlarge
reviewed by:
Anonymous
IP Human 04/21/2017
View

Summary

ApplicationImmunoprecipitation
Sample TestedHuman Dermal Microvascular Endothelial whole cell lysate
SpeciesHuman
LotA-2
Western Blot GLP/EHMT1 PP-B0422-00
Enlarge
reviewed by:
Anonymous
WB Human 04/21/2017
View

Summary

ApplicationWestern Blot
Sample TestedHuman Dermal Microvascular Endothelial whole cell lysate
SpeciesHuman
LotA-2

Product General Protocols

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Video Protocols

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FAQs for GLP/EHMT1 Antibody (PP-B0422-00) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for GLP/EHMT1 Antibody (PP-B0422-00)

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Recent Reviews

4.3
5
1
4
2
3
0
2
0
1
0

Anonymous
07/11/2017
Application: ICC
Species: Human

Anonymous
04/21/2017
Application: IP
Species: Human

Anonymous
04/21/2017
Application: WB
Species: Human

Bioinformatics

Gene Symbol EHMT1
Entrez