G9a/EHMT2 Products

Description

G9A antibody contains ankyrin repeats, suggesting involvement in intracellular protein-protein interaction. G9A is a histone methyltransferase that preferentially methylates Lys-9 of histone H3 and Lys-27 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. G9A is probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1.

Bioinformatics

Entrez	10919 Human
Uniprot	NM_025256 Human Q96KQ7 Human Q96KQ7 (human) Human NP_006700 Human
Product By Gene ID	10919
Alternate Names	EC 2.1.1.43 H3-K9-HMTase 3 EC 2.1.1.- NG36 histone-lysine N-methyltransferase, H3 lysine-9 specific 3 C6orf30 G9A histone methyltransferase BAT8 ankyrin repeat-containing protein Protein G9a FLJ35547 Lysine N-methyltransferase 1C DKFZp686H08213 Histone H3-K9 methyltransferase 3 chromosome 6 open reading frame 30 HLA-B associated transcript 8 KMT1CNG36/G9a G9AEm:AF134726.3 euchromatic histone-lysine N-methyltransferase 2HLA-B-associated transcript 8

Diseases related to G9a/EHMT2

Discover more about diseases related to G9a/EHMT2.

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Leukemia
Inflammation
Neoplasm Metastasis
Neoplasm Invasiveness
Adenocarcinoma
Malignant Neoplasm Of Lung
Cell Transformation, Neoplastic
Hypoxia
Prostatic Neoplasms
Pseudorabies
Carcinogenesis
Malignant Neoplasm Of Pancreas
Cell Invasion
Leukemogenesis

Pathways for G9a/EHMT2

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Methylation
Dna Methylation
Histone Methylation
Regulation Of Gene Expression
Demethylation
Histone Modification
Pathogenesis
Gene Silencing
Cell Migration
Embryo Development
Cell Differentiation
Histone Acetylation
Chromatin Remodeling
Localization
Rna Interference
Cell Adhesion
Positive Regulation Of Gene Expression
Dna Demethylation
Spermatogenesis
Cell Maturation

Research Areas for G9a/EHMT2

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Breast Cancer

PTMs for G9a/EHMT2

Learn more about PTMs related to G9a/EHMT2.

Methylation
Acetylation
Demethylation
Reduction
Phosphorylation
Deacetylation

Bioinformatics Tool for G9a/EHMT2

Discover related pathways, diseases and genes to G9a/EHMT2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.