G9a/EHMT2 Products

Description

G9A antibody contains ankyrin repeats, suggesting involvement in intracellular protein-protein interaction. G9A is a histone methyltransferase that preferentially methylates Lys-9 of histone H3 and Lys-27 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. G9A is probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1.

Bioinformatics

Entrez	10919 Human
Uniprot	NM_025256 Human NP_006700 Human Q96KQ7 (human) Human Q96KQ7 Human
Product By Gene ID	10919
Alternate Names	ankyrin repeat-containing protein BAT8 C6orf30 chromosome 6 open reading frame 30 DKFZp686H08213 EC 2.1.1.- EC 2.1.1.43 euchromatic histone-lysine N-methyltransferase 2HLA-B-associated transcript 8 FLJ35547 G9A histone methyltransferase G9AEm:AF134726.3 H3-K9-HMTase 3 Histone H3-K9 methyltransferase 3 histone-lysine N-methyltransferase, H3 lysine-9 specific 3 HLA-B associated transcript 8 KMT1CNG36/G9a Lysine N-methyltransferase 1C NG36 Protein G9a

Research Areas for G9a/EHMT2

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Breast Cancer