FE65 Antibody [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

FE65 Antibody [Biotin] Summary

Immunogen
Recombinant rat FE65, expressed in bacteria. [Swiss-Prot# P46933]
Localization
Cytoplasmic
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APBB1
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This FE65 antibody is useful in Western blot and Immunoprecipitation. In Western blot a band is seen at ~100 kDa versus the predicted molecular weight of 77 kDa, which corresponds to earlier findings in literature (PMID: 9685356).

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Rat, human, and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for FE65 Antibody [Biotin]

  • adaptor protein FE65a2
  • amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
  • amyloid beta A4 precursor protein-binding, family B, member 1
  • Fe65
  • FE65amyloid beta A4 precursor protein-binding family B member 1
  • MGC:9072
  • Protein Fe65
  • RIR
  • stat-like protein

Background

FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

DyLight 488 Labeled NB110-58360G
DyLight 550 Labeled NB110-58360R
DyLight 650 Labeled NB110-58360C
HRP Labeled NB110-58360H

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Bioinformatics Tool for FE65 Antibody (NB110-58360B)

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Bioinformatics

Gene Symbol APBB1