APBA1 Antibody - BSA Free

Western Blot: APBA1 Antibody [NBP2-41182] - Analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry/Immunofluorescence: APBA1 Antibody [NBP2-41182] - Human brain tissue with APBA1 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

APBA1 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1. The immunogen is located within amino acids 90 - 140 of APBA1. Amino Acid Squence: ARDGYDAERAQDPEDESAY
• Specificity: At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APBA1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Western Blot 0.5 ug/mL
• Theoretical MW: 92 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Human Brain Frontal Lobe Whole Tissue Lysate (Adult Whole Alzheimer's)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for APBA1 Antibody - BSA Free

• Adapter protein X11alpha
• amyloid beta (A4) precursor protein-binding, family A, member 1
• amyloid beta A4 precursor protein-binding family A member 1
• D9S411Eadaptor protein X11alpha
• LIN10
• mint-1
• MINT1amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
• Neuronal Munc18-1-interacting protein 1
• Neuron-specific X11 protein
• phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
• UROP11
• X11A
• X11X11ALPHA

Background

APBA1 is encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APBA1