FE65 Products

Description

Amyloid beta A4 precursor protein-binding family B member 1, also known as FE65, is a signaling adaptor of APP protein. The FE65/APP complex has been shown to translocate into the cell nucleus and regulate gene expression, indicating that FE65 may be critical in the pathogenesis of Alzheimer's disease. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer's Disease patients.

FE65 antibodies are useful tools for research on Alzheimer's disease progression.

Bioinformatics

Entrez	11785 Mouse 29722 Rat 322 Human
Uniprot	AAH10854 Human ABB1_HUMAN Human NM_001164 Human NM_145689 Human NP_001155 Human NP_001155.1 Human NP_663722 Human NP_663722.1 Human
Product By Gene ID	322
Alternate Names	adaptor protein FE65a2 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) amyloid beta A4 precursor protein-binding, family B, member 1 Fe65 FE65amyloid beta A4 precursor protein-binding family B member 1 MGC:9072 Protein Fe65 RIR stat-like protein

Research Areas for FE65

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Cell Cycle and Replication
Neurodegeneration
Neuroscience
Phospho-Specific
Signal Transduction