LRP-1 Antibody (A2Mr alpha-2)

Images

 
Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection ...read more
Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection ...read more
Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection ...read more
Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection ...read more
Immunofluorescence: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2, red in A and Mouse anti Human CD21, clone LB21, green in ...read more
Immunofluorescence: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2, red in A and Mouse anti Human CD21, clone LB21, green in ...read more
Immunofluorescence: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2, red in A and Mouse anti Human CD21, clone LB21, green in ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-Fr, IP, ICC/IF
Clone
A2Mr alpha-2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

LRP-1 Antibody (A2Mr alpha-2) Summary

Immunogen
Purified alpha2 macroglobulin receptor
Specificity
Recognises an epitope in the extracellular region of the 500kD alpha chain.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LRP1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot Non-reducing conditions
  • ELISA Direct
  • Flow Cytometry 1:50-1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Immunofluorescence
Application Notes
For Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Use non-reducing conditions for western blot.
Control
LRP-1 Overexpression Lysate
Publications
Read Publication using NB100-64808.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for LRP-1 Antibody (A2Mr alpha-2)

  • A2MR
  • Alpha-2-Macroglobulin Receptor
  • APOER
  • Apolipoprotein E receptor
  • APR
  • CD91 antigen
  • CD91
  • EC 1.1.1.94
  • EC 3.4.21.9
  • IGFBP3R
  • low density lipoprotein receptor-related protein 1
  • LRP
  • LRP-1
  • LRP1A
  • prolow-density lipoprotein receptor-related protein 1
  • TbetaR-V/LRP-1/IGFBP-3 receptor
  • TGFBR5
  • type V tgf-beta receptor

Background

Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-82820
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NB400-156
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, CyTOF-ready, Dual ISH-IHC
NBP1-78159
Species: Hu, Rt, Po, Bv
Applications: WB, EM, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, PLA, RIA
NB100-80870
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, ELISA, IHC, IHC-P
NB110-60531
Species: Hu, Mu, Rt(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, IP, CyTOF-ready, Flow-IC
NBP1-89334
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-13075
Species: Hu, Mu, Rt, Pm
Applications: WB, DB, ELISA, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, IHC-FrFl
NBP2-57299
Species: Hu
Applications: WB, IHC, IHC-P
H00065108-M02
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, S-ELISA
7270-IL/CF
Species: Hu
NBP2-67279
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-13415
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-79843
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, CyTOF-ready
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Flow-IC
AF7197
Species: Hu, Mu
Applications: WB, IHC, ICC
NBP2-19417
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB100-64808
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-Fr, IP, ICC/IF

Publications for LRP-1 Antibody (NB100-64808)(1)

Reviews for LRP-1 Antibody (NB100-64808) (0)

There are no reviews for LRP-1 Antibody (NB100-64808). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for LRP-1 Antibody (NB100-64808) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB100-64808AF350
Alexa Fluor 405 NB100-64808AF405
Alexa Fluor 488 NB100-64808AF488
Alexa Fluor 532 NB100-64808AF532
Alexa Fluor 594 NB100-64808AF594
Alexa Fluor 647 NB100-64808AF647
Alexa Fluor 700 NB100-64808AF700
Alexa Fluor 750 NB100-64808AF750
Allophycocyanin NB100-64808APC
Biotin NB100-64808B
DyLight 350 NB100-64808UV
DyLight 405 NB100-64808V
DyLight 488 NB100-64808G
DyLight 550 NB100-64808R
DyLight 594 NB100-64808DL594
DyLight 650 NB100-64808C
DyLight 680 NB100-64808FR
DyLight 755 NB100-64808IR
FITC NB100-64808F
HRP NB100-64808H
Janelia Fluor 549 NB100-64808JF549
Janelia Fluor 646 NB100-64808JF646
PE NB100-64808PE
PerCP NB100-64808PCP

Additional LRP-1 Products

Bioinformatics Tool for LRP-1 Antibody (NB100-64808)

Discover related pathways, diseases and genes to LRP-1 Antibody (NB100-64808). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for LRP-1 Antibody (NB100-64808)

Discover more about diseases related to LRP-1 Antibody (NB100-64808).
 

Pathways for LRP-1 Antibody (NB100-64808)

View related products by pathway.

PTMs for LRP-1 Antibody (NB100-64808)

Learn more about PTMs related to LRP-1 Antibody (NB100-64808).

Blogs on LRP-1.

Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysis
By Rosa Moreno, PhD. Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysisPhysiological low levels of oxygen induce normal hypoxic events across biological systems. This hypoxic state activ...  Read full blog post.

Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our LRP-1 Antibody (A2Mr alpha-2) and receive a gift card or discount.

Bioinformatics

Gene Symbol LRP1