E-Cadherin Antibody (967717) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
967717
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

E-Cadherin Antibody (967717) [DyLight 680] Summary

Immunogen
Human embryonic kidney cell line HEK293-derived transfected with human E-Cadherin
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CDH1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
No Preservative
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for E-Cadherin Antibody (967717) [DyLight 680]

  • Arc-1
  • CAD1
  • cadherin 1, E-cadherin (epithelial)
  • cadherin 1, type 1, E-cadherin (epithelial)
  • Cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CAM 120/80
  • CD324 antigen
  • CD324
  • CDH1
  • CDHE
  • cell-CAM 120/80
  • Cell-CAM120/80
  • ECAD
  • ECadherin
  • E-Cadherin
  • Epithelial cadherin
  • LCAM
  • L-CAM
  • UVOE-Cadherin
  • Uvomorulin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for E-Cadherin Antibody (MAB18384FR) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 MAB18384AF350
Alexa Fluor 405 MAB18384AF405
Alexa Fluor 488 MAB18384AF488
Alexa Fluor 532 MAB18384AF532
Alexa Fluor 594 MAB18384AF594
Alexa Fluor 647 MAB18384AF647
Alexa Fluor 700 MAB18384AF700
Alexa Fluor 750 MAB18384AF750
Biotin MAB18384B
DyLight 350 MAB18384UV
DyLight 405 MAB18384V
DyLight 488 MAB18384G
DyLight 550 MAB18384R
DyLight 594 MAB18384DL594
DyLight 650 MAB18384C
DyLight 680 MAB18384FR
DyLight 755 MAB18384IR
HRP MAB18384H

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Bioinformatics Tool for E-Cadherin Antibody (MAB18384FR)

Discover related pathways, diseases and genes to E-Cadherin Antibody (MAB18384FR). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for E-Cadherin Antibody (MAB18384FR)

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Pathways for E-Cadherin Antibody (MAB18384FR)

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PTMs for E-Cadherin Antibody (MAB18384FR)

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Research Areas for E-Cadherin Antibody (MAB18384FR)

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Blogs on E-Cadherin.

Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation
By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...  Read full blog post.

Cathepsin B - a lysosomal protease with potential of an important drug target in neurological diseases and cancer
Cathepsins are a family of lysosomal proteases (serine, aspartic and cysteine proteases) that acts in conjunction with lipases and nucleases to degrade biological macromolecules in the lysosomes (1). While most cathepsins are ubiquitously expressed...  Read full blog post.

SOX2 - a stem cell transcription factor
The SOX gene family encodes a group of highly conserved transcription factors defined by the presence of a conserved high motility group (HMG) DNA-binding domain. They are involved in embryonic development regulation and cell fate determination. Al...  Read full blog post.

Beta-catenin - I am versatile!
Beta-catenin is a cytosolic, 88 kDa intracellular protein associated with cell surface cadherin glycoproteins. It is a member of the larger calcium-dependent catenin family that includes alpha-catenin, beta-catenin, and gamma-catenin (also known as pl...  Read full blog post.

Vimentin: Regulating EMT and Cancer
Vimentin, a member of the intermediate filament (IF) family, is a protein responsible for maintaining cellular integrity and reducing damage caused by stress. The vimentin protein is ubiquitously expressed in normal mesenchymal cells, and recent resea...  Read full blog post.

Carbonic Anhydrase IX Roles in Tumor Growth, Survival and Invasion
Carbonic anhydrase IX (CAIX) is a membrane-associated carbonic anhydrase, strongly induced by hypoxia. CA IX is overexpressed by several cancer cells from many tumor types, and is a component of the pH regulatory system invoked by these cells to comba...  Read full blog post.

E-Cadherin as a Cancer Biomarker
E-cadherin is a calcium-regulated adhesion molecule expressed in most normal epithelial tissues. E-cadherin is also associated with gland formation, stratification, and epithelial polarization, while loss of E-cadherin can cause dedifferentiation and...  Read full blog post.

E-Cadherin in Cell-Cell Adhesion and Cancer Diagnostics
E-Cadherin is a member of the cadherin superfamily and is fundamental player in a wide range of cellular processes such as development, morphology, polarity, migration and tissue integrity. Specifically, E-cadherin is an approximately 100 kDa epitheli...  Read full blog post.

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Bioinformatics

Gene Symbol CDH1