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E-Cadherin Products

Antibodies
E-Cadherin Antibody [Unconjug ...
E-Cadherin Antibody [Unconjugated]
AF748
HAF017). A specific band was detected for E-Cadherin at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot E-Cadherin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry E-Cadherin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). Specific staining was localized to plasma membranes in keratinocytes. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry E-Cadherin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). Magnification shown at 100X (upper panel) and 40X (lower panel). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry E-Cadherin Antibody [Unconjugated]
NL003) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry E-Cadherin Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to dorsal horn. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry E-Cadherin Antibody [Unconjugated]
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western E-Cadherin Antibody [Unconjugated]
AF748) at 0.5ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to glandular cells. " class="big_lightbox" target="_blank"> In-situ Hybridization E-Cadherin Antibody [Unconjugated]
human intestinal organoid culture protocol. (A) The organoids were fixed and stained with a Mouse Anti-Human MUC2 Monoclonal Antibody (Novus Biologicals; Catalog # NBP2-44431; green) to visualize intestinal goblet cells and counterstained with a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF748; red) and DAPI (Catalog # 5748; blue). The image shown was taken at 10x magnification. (B) The organoids were fixed and stained with a Mouse Anti-Human Chromogranin A Monoclonal Antibody (Catalog # MAB90981; green) to visualize enteroendocrine cells and counterstained with a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF748; red) and DAPI (Catalog # 5748; blue). The image shown was taken at 20x magnification." class="big_lightbox" target="_blank"> Immunocytochemistry/ Immunofluorescence E-Cadherin Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, Dual ISH-IHC, ICC/IF
Host: Goat Polyclonal
E-Cadherin Antibody [Unconjug ...
E-Cadherin Antibody [Unconjugated]
AF648
HAF017). A specific band was detected for E-Cadherin at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot E-Cadherin Antibody [Unconjugated]
042-206). This experiment was conducted under reducing conditions and using the 12-230kDa separation system." class="big_lightbox" target="_blank"> Simple Western E-Cadherin Antibody [Unconjugated]
AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry E-Cadherin Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry E-Cadherin Antibody [Unconjugated]
MAB2018). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for E-Cadherin using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # NL001) and for SOX2 using the NorthernLights 493-conjugated Anti-Mouse Secondary Antibody (red; Catalog # NL009). Cells were counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry E-Cadherin Antibody [Unconjugated]
VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membrane and cytoplasm in gastric glands. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry E-Cadherin Antibody [Unconjugated]
HAF017). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank"> Simple Western E-Cadherin Antibody [Unconjugated]
VC004) and DAB chromogen (lower image, yellow-brown). Tissues were counterstained with hematoxylin (blue)." class="big_lightbox" target="_blank"> Dual RNAscope ISH-IHC Compatible E-Cadherin Antibody [Unconjugated]
MAB18382) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human/Mouse E‑Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF648) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA E-Cadherin Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, Dual ISH-IHC, ICC/IF
Host: Goat Polyclonal
E-Cadherin Antibody (7H12)
E-Cadherin Antibody (7H12)
NBP2-19051
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence E-Cadherin Antibody (7H12)
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence E-Cadherin Antibody (7H12)
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence E-Cadherin Antibody (7H12)
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, COMET, mIF
Host: Mouse Monoclonal
Antibody Pairs
E-Cadherin Antibody Pair [HRP ...
E-Cadherin Antibody Pair [HRP]
NBP2-79524
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
ELISA Kits
Human E-Cadherin DuoSet ELISA ...
Human E-Cadherin DuoSet ELISA, 15 ...
DY648
Species: Hu
Applications: ELISA
Human Total E-Cadherin DuoSet ...
Human Total E-Cadherin DuoSet IC E...
DYC4225-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Quantikine Immunoassay Contro ...
Quantikine Immunoassay Control 110...
QC295
Species: Hu
Applications: ELISA, Ctrl
Lysates
E-Cadherin Overexpression Lys ...
E-Cadherin Overexpression Lysate
NBL1-09024
Species: Hu
Applications: WB
Proteins
Recombinant Human E-Cadherin ...
Recombinant Human E-Cadherin Prote...
8505-EC
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse E-Cadherin ...
Recombinant Mouse E-Cadherin Prote...
8875-EC
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Rat E-Cadherin Fc ...
Recombinant Rat E-Cadherin Fc Chim...
8144-EC
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

E-cadherin, or epithelial cadherin, is an cell-cell adhesion glycoprotein important to cellular processes such as morphology, polarity, development, tissue integrity and migration. E cadherin's extracellular domain interacts with other E-cadherin protein on adjacent epithelial cells to establish adhesion between them. E cadherin has also been identified as a tumor and metastasis suppressor, and its mutations have been linked to various forms of cancer.

Bioinformatics

Entrez Mouse
Bovine
Human
Rat
Human
Uniprot Human
Human
Human
Human
Mouse
Human
Human
Human
Product By Gene ID 999
Alternate Names
  • Arc-1
  • cadherin 1, E-cadherin (epithelial)
  • cadherin 1, type 1, E-cadherin (epithelial)
  • cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CAM 120/80
  • CD324 antigen
  • CD324
  • CDHE
  • cell-CAM 120/80
  • ECAD
  • E-cadherin
  • Epithelial cadherin
  • LCAM
  • UVOE-Cadherin
  • uvomorulin
  • Uvomorulin

Research Areas for E-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Phospho-Specific
Plasma Membrane Markers
Signal Transduction

Related E-Cadherin Blog Posts

Check out the latest blog posts on E-Cadherin.
E-Cadherin in Cell-Cell Adhesion and Cancer Diagnostics
E-Cadherin is a member of the cadherin superfamily and is fundamental player in a wide range of cellular processes such as development, morphology, polarity, migration and tissue integrity. Specifically, E-cadherin is an approximately 100 kDa epitheli...    Read more.
E-Cadherin as a Cancer Biomarker
E-cadherin is a calcium-regulated adhesion molecule expressed in most normal epithelial tissues. E-cadherin is also associated with gland formation, stratification, and epithelial polarization, while loss of E-cadherin can cause dedifferentiation and ...    Read more.
Carbonic Anhydrase IX Roles in Tumor Growth, Survival and Invasion
Carbonic anhydrase IX (CAIX) is a membrane-associated carbonic anhydrase, strongly induced by hypoxia. CA IX is overexpressed by several cancer cells from many tumor types, and is a component of the pH regulatory system invoked by these cells to comba...    Read more.
Vimentin: Regulating EMT and Cancer
Vimentin, a member of the intermediate filament (IF) family, is a protein responsible for maintaining cellular integrity and reducing damage caused by stress. The vimentin protein is ubiquitously expressed in normal mesenchymal cells, and recent resea...    Read more.
SOX2 - a stem cell transcription factor
The SOX gene family encodes a group of highly conserved transcription factors defined by the presence of a conserved high motility group (HMG) DNA-binding domain. They are involved in embryonic development regulation and cell fate determination. Al...    Read more.
Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation
By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...    Read more.
Beta-catenin - I am versatile!
Beta-catenin is a cytosolic, 88 kDa intracellular protein associated with cell surface cadherin glycoproteins. It is a member of the larger calcium-dependent catenin family that includes alpha-catenin, beta-catenin, and gamma-catenin (also known as pl...    Read more.
Cathepsin B - a lysosomal protease with potential of an important drug target in neurological diseases and cancer
Cathepsins are a family of lysosomal proteases (serine, aspartic and cysteine proteases) that acts in conjunction with lipases and nucleases to degrade biological macromolecules in the lysosomes (1). While most cathepsins are ubiquitously expressed...    Read more.
Read more E-Cadherin related blogs.