DGAT1 Antibody [DyLight 405]


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Product Details

Reactivity Hu, Mu, Rt, Bv, Ze, Gt, Pm, ShSpecies Glossary
Applications WB, ICC/IF
DyLight 405

DGAT1 Antibody [DyLight 405] Summary

A synthetic peptide made to an internal region (within residues 200-300) of human DGAT1. [Swiss-Prot# O75907]
Endoplasmic reticulum; endoplasmic reticulum membrane multi-pass membrane protien.
Predicted Species
Primate (100%), Goat (100%), Sheep (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
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  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This DGAT1 antibody is useful for Western Blot analysis and Immunocytochemistry/Immunofluorescence. In Western Blot, a band is seen at ~55 kDa. In ICC/IF, staining was observed in the endoplasmic reticulum and cytoplasm of HepG2 cells. This antibody is not applicable for IHC-paraffin embedded sections.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with primate, sheep, and goat based on 100% sequence homology.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DGAT1 Antibody [DyLight 405]

  • ACAT-related gene product 1
  • AGRP1
  • ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1
  • DGATACAT related gene product 1
  • diacylglycerol O-acyltransferase 1
  • diacylglycerol O-acyltransferase homolog 1 (mouse)
  • diacylglycerol O-acyltransferase homolog 1
  • Diglyceride acyltransferase
  • EC 2.3.1
  • EC


Anabolic signals such as glucose, insulin etc. enhance the transcription of lipogenic enzymes responsible for converting excessive carbohydrates into triglycerides, whereas, DGAT1 (diacylglycerol O-acyltransferase 1) is an enzyme that facilitates the conversion of fatty acids to triglycerides. DGAT1 is a multi-pass membrane protein localized in endoplasmic reticulum which catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2, it is not essential for survival, and is involved in VLDL assembly. In liver, DGAT1 plays a key role in esterifying exogenous fatty acids to glycerol, and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. Moreover, it acts as the major acyl-CoA retinol acyltransferase (ARAT) in skin tissues, wherein, it maintains the retinoid homeostasis for preventing retinoid toxicity responsible for skin and hair disorders.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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DGAT1 NB110-41487V

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Blogs on DGAT1.

Can you DGAT? DGAT1 & DGAT2 Antibodies for Metabolic Pathway Research
Triacylglycerols (triglycerides) (TGs) are the major storage molecules of metabolic energy and FAs in most living organisms. Excessive accumulation of TGs, however, is associated with human diseases, such as obesity, diabetes mellitus, and steatohepat...  Read full blog post.

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Gene Symbol DGAT1