Cytochrome P450 17A1 Antibody - BSA Free

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Western Blot: Cytochrome P450 17A1 Antibody [NBP3-35404] - Western blot analysis of lysates from rat testis, using Cytochrome P450 17A1 Rabbit pAb at 1:500 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

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Catalog# & Formulation Size Price

Cytochrome P450 17A1 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit Cytochrome P450 17A1 Antibody - BSA Free (NBP3-35404) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human Cytochrome P450 17A1 (NP_000093.1).

Sequence:
LSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAEGST
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CYP17A1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500 - 1:2000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Cytochrome P450 17A1 Antibody - BSA Free

  • CPT7
  • CYP17
  • CYP17A1
  • CYPXVII
  • Cytochrome P450 17A1
  • cytochrome p450 XVIIA1
  • cytochrome P450, family 17, subfamily A, polypeptide 1
  • cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenalhyperplasia
  • Cytochrome P450c17
  • Cytochrome P450-C17
  • EC 1.14.14.19
  • EC 1.14.14.32
  • EC 1.14.99
  • P450C17
  • P450C17CYPXVII
  • S17AH

Background

The CYP17A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP17A1 protein localizes to the endoplasmic reticulum. CYP17A1 has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in the CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. (provided by RefSeq, Jul 2008)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CYP17A1