Species: Hu
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Ca, Fe
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The CYP17A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP17A1 protein localizes to the endoplasmic reticulum. CYP17A1 has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in the CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. (provided by RefSeq, Jul 2008)
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
1586 |
| Alternate Names |
- CPT7
- cyp17
- CYP17A1
- cytochrome p450 XVIIA1
- cytochrome P450, family 17, subfamily A, polypeptide 1
- cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenalhyperplasia
- Cytochrome P450c17
- Cytochrome P450-C17
- EC 1.14.99
- P450C17
- P450C17CYPXVII
- S17AH
|
Research Areas for Cytochrome P450 17A1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
