CD44 Antibody (MEM-263) [FITC]

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Product Details

Summary
Reactivity Hu, Po, CaSpecies Glossary
Applications Flow
Clone
MEM-263
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

CD44 Antibody (MEM-263) [FITC] Summary

Immunogen
COS-7 cells, African Green Monkey (NM_000610.3).
Marker
Cell Membrane Marker
Specificity
The antibody MEM-263 reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. HLDA III; WS Code T 155
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD44
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.
Publications
Read Publications using
NBP1-42789 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
15mM Sodium Azide
Purity
Protein A purified

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for CD44 Antibody (MEM-263) [FITC]

  • CD44 antigen
  • CD44 molecule (Indian blood group)
  • CD44
  • CD44R
  • CDw44
  • cell surface glycoprotein CD44
  • chondroitin sulfate proteoglycan 8
  • CSPG8
  • ECMR-III
  • epican
  • Extracellular matrix receptor III
  • GP90 lymphocyte homing/adhesion receptor
  • HCAM
  • HCELL
  • hematopoietic cell E- and L-selectin ligand
  • Heparan sulfate proteoglycan
  • Hermes antigen
  • homing function and Indian blood group system
  • HUTCH-I
  • Hyaluronate receptor
  • IN
  • LHR
  • MC56
  • MDU2
  • MDU2CD44 antigen (homing function and Indian blood group system)
  • MDU3
  • MDU3CDW44
  • MIC4
  • MIC4MGC10468
  • MUTCH-I
  • Pgp1
  • PGP-1
  • PGP-I
  • Phagocytic glycoprotein 1
  • Phagocytic glycoprotein I

Background

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD44 Antibody (NBP1-42789)(2)

We have publications tested in 1 confirmed species: Porcine.

We have publications tested in 1 application: FLOW.


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FLOW
(1)
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Porcine
(1)
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Showing Publications 1 - 2 of 2.
Publications using NBP1-42789 Applications Species
Huang CC, Tsai HW, Lee WY et al. A translational approach in using cell sheet fragments of autologous bone marrow-derived mesenchymal stem cells for cellular cardiomyoplasty in a porcine model Biomaterials 2013 Jun [PMID: 23528228] (FLOW, Porcine) FLOW Porcine
Leukocyte Typing III, McMichael AJ et al (Eds). Oxford University Press (1987).

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD44
Entrez