CD31/PECAM-1 Antibody (158-2B3) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
158-2B3
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

Order Details

CD31/PECAM-1 Antibody (158-2B3) [Alexa Fluor® 532] Summary

Immunogen
Stimulated human leukocytes (Workshop VI)
Localization
Cell surface and cytoplasm of endothelial cells
Marker
Endothelial Cell Marker
Specificity
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PECAM1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD31/PECAM-1 Antibody (158-2B3) [Alexa Fluor® 532]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • EndoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CD31/PECAM-1 Antibody (NBP2-47784AF532) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47784AF350
Alexa Fluor 405 NBP2-47784AF405
Alexa Fluor 488 NBP2-47784AF488
Alexa Fluor 532 NBP2-47784AF532
Alexa Fluor 594 NBP2-47784AF594
Alexa Fluor 647 NBP2-47784AF647
Alexa Fluor 700 NBP2-47784AF700
Alexa Fluor 750 NBP2-47784AF750
Allophycocyanin NBP2-47784APC
DyLight 350 NBP2-47784UV
DyLight 405 NBP2-47784V
DyLight 488 NBP2-47784G
DyLight 550 NBP2-47784R
DyLight 594 NBP2-47784DL594
DyLight 650 NBP2-47784C
DyLight 680 NBP2-47784FR
DyLight 755 NBP2-47784IR
FITC NBP2-47784F
Janelia Fluor 549 NBP2-47784JF549
Janelia Fluor 646 NBP2-47784JF646
PE NBP2-47784PE
PerCP NBP2-47784PCP

Additional CD31/PECAM-1 Products

Bioinformatics Tool for CD31/PECAM-1 Antibody (NBP2-47784AF532)

Discover related pathways, diseases and genes to CD31/PECAM-1 Antibody (NBP2-47784AF532). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD31/PECAM-1 Antibody (NBP2-47784AF532)

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Research Areas for CD31/PECAM-1 Antibody (NBP2-47784AF532)

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Blogs on CD31/PECAM-1.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Bioinformatics

Gene Symbol PECAM1